Evaluation of neuroprotection by lithium and valproic acid against ouabain-induced cell damage

Bipolar Disorders

Volumn 4, Issue 3, 2002, Pages 201-206

  Hennion, J P ^a   Adnan El Masri, M ^a   Huff, Mary O ^a   El Mallakh, Rif S ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Bipolar; lithium; Manic depression; Neuroblastoma cells; Neuroprotection; SH SY5Y cells; Valproate; Valproic acid

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); DNA FRAGMENT; ENZYME INHIBITOR; LACTATE DEHYDROGENASE; LITHIUM; OUABAIN; VALPROIC ACID;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA DEGRADATION; ENZYME RELEASE; HOMEOSTASIS; HUMAN; HUMAN CELL; ION TRANSPORT; MANIA; MANIC DEPRESSIVE PSYCHOSIS; NERVE CELL LESION; NEUROBLASTOMA CELL; NEUROPROTECTION; NEUROTOXICITY; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

ANTIMANIC AGENTS; APOPTOSIS; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; L-LACTATE DEHYDROGENASE; LITHIUM; NA(+)-K(+)-EXCHANGING ATPASE; NEUROBLASTOMA; NEURONS; NEUROPROTECTIVE AGENTS; OUABAIN; TUMOR CELLS, CULTURED; VALPROIC ACID;

EID: 0036272280     PISSN: 13985647     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-5618.2002.01162.x     Document Type: Article

References (46)

1. Clinical and biochemical analysis of a case or manic depressive psychosis showing regular weekly cycles
2. Mineral metabolism in mania
3. Mineral metabolism, mania, and melanocholia
4. Elevated platelet intracellular calcium concentration in bipolar depression
5. Abnormal intracellular calcium ion concentration in platelets and lymphocytes of bipolar patients
6. Erythrocyte membrane cation carrier in depressive illness
7. Meta-analysis of erythrocyte Na,K-ATPase activity in bipolar illness
8. Leukocyte transmembrane potential in bipolar illness
9. Nerve conduction velocity and H-reflex recovery in bipolar illness
10. Alpha2 isoform of the Na, K-adenosine triphosphatase is reduced in temporal cortex of bipolar individuals
11. The Na, K-ATPase hypothesis for bipolar illness
12. Open field is more sensitive than automated activity monitor in documenting ouabain-induced hyperlocomotion in the development of an animal model for bipolar illness
13. Mood stabilizers and ion regulation
14. Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx
15. Lithium protects rat cerebellar granule cells against apoptosis induced by anticonvulsants, phenytoin and carbamazepine
16. Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats
17. Lithium protects against ouabain-induced cell death
18. A novel evidence of different mechanisms of lithium and valproate neuroprotective action on human SY5Y neuroblastoma cells: Caspase-3 dependency
19. Regulation of signal transduction pathways by mood-stabilizing agents: Implications for the pathophysiology and treatment of bipolar disorder
20. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS
21. Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression: A prominent role in neuroprotection against excitotoxicity
22. Programmed cell death and Bcl-2 protection in very low oxygen
23. Bcl-2 gene family in the nervous system
24. Bcl-2 promotes regeneration of severed axons in mammalian CNS
25. A molecular mechanism for the effect of lithium on development
26. Lithium attenuates p53 levels in human neuroblastoma SH-SY5Y cells
27. The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase 3
28. Cyclic AMP responsive element binding protein phosphorylation and DNA binding is decreased by chronic lithium but not valproate treatment of SH-SY5Y cells
29. A quick and simple method for the quantification of lactate dehydrogenase release in measurements of cellular toxicity and tumor necrosis factor (TNF) activity
30. Characterization of the cell death process induced by staurosporine in human neuroblastoma cell lines
31. Detergent and enzyme treatment of apoptotic cells for the observation of DNA fragmentation
32. Ouabain induction of cycling of multiple spike responses in hippocampal slices is delayed by lithium
33. Antiarrhythmic effect of lithium
34. The effect of prophylactic and therapeutic administration of lithium on ventricular tacharrhythmia
35. Lithium prevents ouabain-induced behavioral changes: Toward an animal model for manic depression
36. The effect of lithium on the hypermotility response to the central administration of ouabain in the rat
37. The ionic mechanism of lithium action
38. 2A receptor activation
39. +-ATPase the link between phosphoinositide metabolism and bipolar disorder?
40. Myo-inositol monophosphatase diverse effects of lithium, carbamazepine, and valproate
41. Differential effects of mood stabilizers on Fos/Jun proteins and AP-1 DNA binding activity in human neuroblastoma SH-SY5Y cells
42. A direct hepatotoxic effect of valproic acid
43. Valproic acid hepatic fatalities: A retrospective review
44. Side effects of valproate