Morphine down regulates human vascular tissue estrogen receptor expression determined by real-time RT-PCR

Neuroendocrinology Letters

Volumn 23, Issue 2, 2002, Pages 95-100

  Cadet, Patrick ^a   Mantione, Kirk ^a   Bilfinger, Thomas V ^a   Stefano, George B ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Estrogen; Estrogen receptors; Human vascular endothelial cells; Morphine; Nitric oxide

Indexed keywords

ALKALOID; COMPLEMENTARY DNA; DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLORNITHYLTHREONYLPENICILLAMINYLTHREONINAMIDE 2,7 DISULFIDE; ELECTROLYTE; ESTROGEN RECEPTOR BETA; FENTANYL CITRATE; HEPARIN; MORPHINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR ANTAGONIST; NALOXONE; NITRIC OXIDE SYNTHASE; OPIATE; PRIMER RNA; RNA; SUFENTANIL;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG MECHANISM; DRUG RECEPTOR BINDING; ENDOTHELIUM CELL; FEMALE; GENE EXPRESSION; GENE SEQUENCE; HEART ATRIUM; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; RNA PROBE; SAPHENOUS VEIN; SEQUENCE HOMOLOGY; VASCULAR TISSUE;

EID: 0036261332     PISSN: 0172780X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Acute exposure of estrogen to human endothelia results in nitric oxide release mediated by an estrogen surface receptor coupled to intracellular calcium transients
2. Estradiol coupling to endothelial nitric oxide production stimulates GnRH release from rat median eminence
3. Autoimmunovascular regulation: Morphine and anandamide stimulated nitric oxide release
4. The μ3 opiate receptor subtype
5. Human vascular and cardiac endothelia express mu opiate receptor transcripts
6. Median eminence nitric oxide signaling
7. Endogenous morphine
8. Real-time RT-PCR measurement of the modulation of Mu opiate receptor expression by nitric oxide in human mononuclear cells
9. Morphine and anandamide coupling to nitric oxide stimulated GnRH and CRF release from rat median eminence: Neurovascular regulation
10. Cryopreserved veins used for myocardial revascularization: A 5 year experience and a possible mechanism for their increased failure
11. Presence of the mu3 opiate receptor in endothelial cells: Coupling to nitric oxide production and vasodilation
12. Morphine-induced conformational changes in human monocytes, granulocytes, and endothelial cells and in invertebrate immunocytes and microglia are mediated by nitric oxide
13. Opioid and opiate immunoregulatory processes
14. Long-term exposure of human blood vessels to HIV gp120, morphine and anandamide increases endothelial adhesion of monocytes: Uncoupling of Nitric Oxide
15. Presence of endogenous morphine and morphine 6 glucuronide in human heart tissue
16. An hormonal role for endogenous opiate alkaloids: Vascular tissues
17. Nitric oxide autoregulation and its significance
18. Estradiol coupling to human monocyte nitric oxide release is dependent on intracellular calcium transients: Evidence for an estrogen surface receptor
19. Basal nitric oxide limits immune, nervous and cardiovascular excitation: Human endothelia express a mu opiate receptor
20. Modulation of hypothalamic mu-opioid receptor density by estrogen: A quantitative autoradiographic study of the female C57BL/6J mouse
21. Decrease of the number of opioid receptors and of the responsiveness to morphineduring neuronal differentiation induced by 17beta-estradiol in estrogen receptor-transfected neuroblastoma cells (SK-ER3)
22. Estrogen-induced alteration of mu-opioid receptor immunoreactivity in the medial preoptic nucleus and medial amygdala
23. Estrogen regulation of mu-opioid receptor mRNA in the forebrain of female rats
24. Estrogen regulation of mu opioid receptor density in hypothalamic premammillary nuclei
25. Human aortocoronary grafts and nitric oxide release: Relationship to pulsatile pressure
26. Endogenous morphine and related opiates, a new class of chemical messengers
27. Endogenous morphine levels increase following cardiac surgery: Decreasing proinflammatory cytokine levels and immunocyte activity
28. New role for estrogen in cancer?