Decrease of the number of opioid receptors and of the responsiveness to morphine during neuronal differentiation induced by 17β-estradiol in estrogen receptor-transfected neuroblastoma cells (SK-ER3)

Neuroendocrinology

Volumn 69, Issue 1, 1999, Pages 54-62

  Maggi, Roberto ^a   Ma, Zhi Qing ^b   Pimpinelli, Federica ^b   Maggi, Adriana ^b   Martini, Luciano ^b  

^a Ist Naz Stud e la Cura dei Tumori   (Italy)

^b NONE

Author keywords

Development; Gonadal steroids; Molecular neuroendocrinology; Neuroblastoma; Opiate peptides; Opiate receptors

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; ANTIESTROGEN; COMPLEMENTARY DNA; DIPRENORPHINE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; ESTRADIOL; ESTROGEN RECEPTOR; FULVESTRANT; MORPHINE; OPIATE RECEPTOR; TRITIUM;

ARTICLE; CONTROLLED STUDY; DNA TRANSFECTION; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; NERVE CELL DIFFERENTIATION; NEUROBLASTOMA CELL; PRIORITY JOURNAL; RADIOASSAY; RECEPTOR DENSITY;

CELL DIFFERENTIATION; CELL DIVISION; CYCLIC AMP; DIPRENORPHINE; ESTRADIOL; HUMANS; MORPHINE; NARCOTIC ANTAGONISTS; NEUROBLASTOMA; NEURONS; RECEPTORS, ESTROGEN; RECEPTORS, OPIOID; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; TRANSFECTION; TRITIUM; TUMOR CELLS, CULTURED;

EID: 0032972782     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000054403     Document Type: Article

References (48)

1. McEwen B: Steroid hormones are multifunctional messengers to the brain. Trends Endocrinol Metab 1991;1:62-67.
2. Ferreira A, Caceres A: Estrogen-enhanced neurite growth. Evidence for a selective induction of tau and stable microtubules. J Neurosci 1991l11:392-400.
3. Frankfurt M, Could E, Woolley CS, McEwen BS: Gonadal steroids modify dendritic spine density in ventromedial, hypothalamic neurons. A Golgi study in the adult rat. Neuroendocrinology 1990;51:530-535.
4. Gibson DA, Vernadakis A: Response of chick cerebellum in culture to L-dopa and estradiol. Life Sci 1975;15:639-643.
5. Wise PM, Scarbrough K, Weiland NG, Larson GH: Diurnal pattern of proopiomelanocortin gene expression in the arcuate nucleus of proestrus, ovariectomized, and steroid-treated rats: A possible role in cyclic luteinizing hormone secretion. Mol Endocrinol 1990;4:886-892.
6. Piva F, Limonta P, Dondi D, Pimpinelli F, Martini L, Maggi R: Effects of steroids on the brain opioid systems. J Steroid Biochem Mol Biol 1995;53:343-348.
7. Maggi R, Dondi D, Rovati GE, Martini L, Piva F, Limonta P: Binding characteristics of hypothalamic mu opioid receptors throughout the estrous cycle in the rat. Neuroendocrinology 1993;8:366-372.
8. 3H]dihydromorphine) opioid receptors in the rat. Dev Brain Res 1991;62:131-136.
9. Dondi D, Maggi R, Panerai AE, Piva F, Limonta P: Hypothalamic opiatergic tone during pregnancy, parturition and lactation in the rat. Neuroendocrinology 1991;53:460-466.
10. Hammer RP Jr, Mateo AR, Bridges RS: Hormonal regulation of medial preoptic mu-opiate receptor density before and after parturition. Neuroendocrinology 1992;56:38-45.
11. Wilkinson M, Brawer JR, Wilkinson DA: Gonadal steroid-induced modification of opiate binding sites in anterior hypothalamus of female rats. Biol Reprod 1985;32:501-506.
12. Weiland NG, Wise PM: Estrogen and progesterone regulate opiate receptor density in multiple brain regions. Endocrinology 1990;126: 804-808.
13. Dondi D, Limonta P, Maggi R, Piva F: Effects of ovarian hormones on brain opioid binding sites in castrated female rats. Am J Physiol 1992;263:E507-E511.
14. Maggi R, Martini L, Piva F: Effect of ovariectomy on the binding characteristics of hypothalamic mu opioid receptors in the rat. Endocr Regul 1994;28:171-178.
15. Brown LL, Pasi S, Etgen AM: Estrogen regulation of μ opioid receptor density in hypothalamic premammillary nuclei. Brain Res 1996; 742:347-351.
16. Mogil J, Sternberg W, Kest B, Marek P, Liebeskind J: Sex differences in the antagonism of swim stress-induced analgesia: Effects of gonadectomy and estrogen replacement. Pain 1993;53:17-25.
17. Grain S: Spinal cord tissue culture models for analyses of opioid analgesia, tolerance and plasticity. NIDA Res Monogr 1984;54:260-292.
18. Crain S, Shen K: Ultra-low concentrations of naloxone selectivity antagonize excitatory effects of morphine on sensory neurons, thereby increasing its antinociceptive potency and attenuating tolerance/dependence during chronic treatment. Proc Natl Acad Sci USA 1995;92: 10540-10544.
19. Nomikos G, Spyraki C, Kazandjian A, Sfikakis A: Estrogen treatment to ovariectomized rats modifies morphine-induced behavior. Pharmacol Biochem Behav 1987;27:611-617.
20. Ratka A, Simpkins J: A modulatory role for luteinizing hormone-releasing hormone in nociceptive responses of female rats. Endocrinology 1990;127:667-673.
21. Ratka A, Simpkins J: Effects of estradiol and progesterone on the sensitivity to pain and on morphine-induced antinociception in female rats. Horm Behav 1991;25:217-228.
22. Pahlman S, Mamaeva S, Meyerson G, Mattsson ME, Bjelfman C, Ortoft E, Hammerling U: Human neuroblastoma cells in culture: A model for neuronal cell differentiation and function. Acta Physiol Scand Suppl 1990;592:25-37.
23. Yu CV, Sadée W: Efficacy and tolerance of narcotic analgesics at the mu opioid receptor in differentiated human neuroblastoma cells. J Pharmacol ExpTher 1988;245:350-355.
24. Ma ZQ, Spreafico E, Pollio G, Santagati S, Conti E, Cattaneo E, Maggi A: Activated estrogen receptor mediates growth arrest and differentiation of a neuroblastoma cell line. Proc Natl Acad Sci USA 1993;90:3740-3744.
25. Ma ZQ, Santagati S, Patrone C, Pollio G, Vegeto E, Maggi A: Insulin-like growth factors activate estrogen receptor to control the growth and differentiation of the human neuroblastoma cell line SK-ER3. Mol Endocrinol 1994;8: 910-918.
26. Santagati S, Ma ZQ, Ferrarini C, Pollio G, Maggi A: Expression of early genes in estrogen-induced phenotypic conversion of neuroblastoma cells. J Neuroendocrinol 1995;7:875-879.
27. Agrati P, Gamier M, Patrone C, Pollio G, Santagati S, Vegeto E, Maggi A: SK-ER3 neuroblastoma cells as a model for the study of estrogen influence on neural cells. Brain Res Bull 1997;44:519-523.
28. Biedler JL, Roffler-Tarlov S, Schachner M, Freedman LS: Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res 1978;38:3751-3757.
29. Polastron J, Mur M, Mazarguil H, Puget A, Meunier J-C, Jauzac P: SK-N-BE: A human neuroblastoma cell line containing two subtypes of δ-opioid receptors. J Neurochem 1994; 62:898-906.
30. Palazzi E, Ceppi E, Guglielmetti F, Catozzi L, Amoroso D, Groppetti A: Biochemical evidence of functional interaction between μ-and δ-opioid receptors in SK-N-BE neuroblastoma cell line. J Neurochem 1996;67:138-144.
31. Wolleman M: Recent developments in the research of opioid receptor subtype molecular characterization. J Neurochem 1990;54:1095-1101.
32. Maggi R, Pimpinelli F, Martini L, Piva F: Characterization of functional opioid delta receptors in a luteinizing hormone-releasing hormone producing neuronal cell Jine. Endocrinology 1995;136:289-295.
33. 125I-β-endorphin opioid receptor sites in NG108-15, but not SK-N-SH neuroblastoma cells. Life Sci 1991;49:PL147-PL152.
34. Bradford MM: A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the pinciple of protein-dye binding. Anal Biochem 1976;72:248-254.
35. max in ligand binding experiments. I. Homologous and heterologous binding to one classes of sites. Anal Biochem 1988;174:636-649.
36. Munson PJ, Rodbard D: LIGAND: A versatile computerized approach for characterization of ligand-binding systems. Anal Biochem 1980; 107:220-239.
37. Maggi R, Rovati GE: MacEllipse, a graphical aid to the problem of the joint confidence region: A practical example for ligand binding experiments. Pharmacol Res 1993;28:1-8.
38. Leslie FM: Methods used for the study of opioid receptors. Pharmacol Rev 1987;39: 197-249.
39. Pasternak GW, Wood PJ: Multiple mu opiate receptors. Life Sci 1986;38:1889-1898.
40. Maggi R, Pimpinelli F, Casulari LA, Piva F, Martini L: Antiprogestins inhibit the binding of opioids to μ receptors in nervous membrane preparations. Eur J Pharmacol 1996;301:169-177.
41. Schwarz S, Pohl P: Steroid and opioid receptors. J Steroid Biochem Mol Biol 1994;48:391-402.
42. Kuramoto T, Werrbach-Perez K, Perez-Polo J, Haber B: Membrane properties of a human neuroblastoma. II. Effects of differentiation. J Neurosci Res 1981;6:441-449.
43. Reynolds C, Perez-Polo J: Induction of neurite outgrowth in the IMR-32 human neuroblastoma cell line by nerve growth factor. J Neurosci Res 1981;6:319-325.
44. Zadina JE, Harrison LM, Ge LJ, Kastin AJ, Chang SL: Differential regulation of mu and delta opiate receptors by morphine, selective agonists and antagonists and differentiating agents in SH-SY5Y human neuroblastoma cells. J Pharmacol Exp Ther 1994;270:1086-1096.
45. Yu CV, Hochhaus G, Chang F-S, Richards ML, Boume HR, Sadée W: Differentiation of human neuroblastoma cells: Marked potentiation of prostaglandin E-stimulated accumulation of cyclic AMP by retinoic acid. J Neurochem 1988;51:1892-1899.
46. Ratka A, Hochhaus G, Wissler RN, Simpkins JW: cAMP accumulation in opioid-sensitive SH-SY5Y neuroblastoma cells is modified by estradiol and progesterone. Mol Cell Endocrinol 1991;78:155-162.
47. B-mediated hyperpolarization of hypothalamic arcuate neurons. J Neurosci 1992;12:2745-2750.
48. Quinones-Jenab V, Jenab S, Ogawa S, Inturrisi C, Pfaff DW: Estrogen regulation of μ opioid receptor mRNA in the forebrain of female rats. Mol Brain Res 1997;47:134-138.