Alterations in phosphatidylcholine metabolism of stretch-injured cultured rat astrocytes

Journal of Neurochemistry

Volumn 68, Issue 5, 1997, Pages 1904-1910

  Lamb, Robert G ^a   Harper, Courtney C ^a   McKinney, Jerry S ^a   Rzigalinski, Beverly A ^a   Ellis, Earl F ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antioxidants; Cultured astrocytes; Oxyradical scavengers; Phosphatidylcholine biosynthesis; Phosphocholine cytidylyltransferase activity; Phospholipase activity; Stretch induced cell injury

Indexed keywords

ANTIOXIDANT; ARACHIDONIC ACID; DEFEROXAMINE; LACTATE DEHYDROGENASE; OXYGEN RADICAL; PHOSPHATIDYLCHOLINE; PHOSPHOLIPASE A2; PHOSPHOLIPASE C; PHOSPHORYLCHOLINE; SCAVENGER;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN INJURY; CELL DAMAGE; CONTROLLED STUDY; ENZYME ACTIVITY; NEWBORN; NONHUMAN; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; RAT; STRETCHING;

ANIMALIA; HABER; LETHRINIDAE; OXY;

EID: 0030992173     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.68051904.x     Document Type: Article

References (37)

1. Amruthesh S. C., Boerschel M. F., McKinney J. S., Willoughby K. A., and Ellis E. F. (1993) Metabolism of arachidonic acid to epoxyeicosatrienoic acids, hydroxyeicosatetraenoic acids, and prostaglandins in cultured rat hippocampal astrocytes. J. Neurochem. 61, 150-159.
2. Bligh E. G. and Dyer W. J. (1959) A rapid method of total lipid extraction and purification. Can. J. Biochem. 37, 911-917.
3. Chan P. H., Chen S. F., and Yu A. C. H. (1988) Induction of intracellular superoxide radical formation by arachidonic acid and by polyunsaturated fatty acids in primary astrocyte cultures. J. Neurochem. 50, 1185-1193.
4. 4 biotransformation on the activation of rat liver phospholipase C in vitro. Toxicol. Appl. Pharmacol 95, 200-207.
5. Ellis E. F., Wright K. F., Wei E. P., and Kontos H. A. (1981) Cyclooxygenase products of arachidonic acid metabolism in cat cerebral cortex after experimental concussive brain injury. J. Neurochem. 37, 892-896.
6. Ellis E. F., McKinney J. S., Willoughby K. A., Liang S., and Povlishock J. T. (1995) A new model for rapid stretch-induced injury of cells in culture: characterization of the model using astrocytes. J. Neurotrauma 12, 325-339.
7. Gamache D. A., Fawzy A. A., and Franson R. C. (1988) Preferential hydrolysis of peroxidized phospholipid by lysosomal phospholipase C. Biochim. Biophys. Acta 958, 116-124.
8. Haber F. and Weiss J. J. (1934) The catalytic decomposition of hydrogen peroxide by iron salts. Proc. R. Soc. Lond. A: Math. Phvs. Sci. 147, 332-351.
9. Hall E. D. (1993) Lipid antioxidants in acute central nervous system injury. Ann. Emerg. Med. 22, 1022-1027.
10. Hall E. D. Braughler J. M., Yonkers P. A., Smith S. L., Linesman K. L. Means E. D., Scherch H. M., Von Voigtlander P. F., Lahti R. A., and Jon Jacobson E. (1991) U-78517F: a potent inhibitor of lipid peroxidation with activity in experimental brain injury and ischemia. J. Pharmacol. Exp. Ther. 258, 688-694.
11. Hall E. D., Andrus P. K., and Yonkers P. A. (1993) Brain hydroxyl radical formation in acute experimental head injury. J. Neurochem. 60, 588-594.
12. Huband S. and Lamb R. (1995) Hepatocellular phospholipases A and C are activated by oxyradicals generated by a Haber-Weiss reaction. (Abstr.) FASEB J. 9, A957.
13. Ishidate K., Tsuruoka M., and Kakazawa Y. (1980) Alteration in enzyme activities of de novo phosphatidylcholine biosynthesis in rat liver by treatment with typical inducers of microsomal drug-metabolizing system. Biochim. Biophys. Acta 620, 49-58.
14. Kontos H. A. and Wei E. P. (1986) Superoxide production in experimental brain injury. J. Neurosurg. 64, 803-807.
15. Kukreja R. C., Kontos H. A., Hess M. L., and Ellis E. F. (1986) PGH synthase and lipoxygenase generate superoxide in the presence of NADH or NADPH. Circ. Res. 59, 612-619.
16. Lamb R. G. and Fallon H. J. (1970) The formation of monoacylglycerol-phosphate from sn-glycerol-3-phosphate by a rat liver particulate preparation. J. Biol. Chem. 245, 3075-3083.
17. Lamb R. G. and Schwertz D. W. (1982) The effects of bromobenzene and carbon tetrachloride exposure in vitro on the phospholipase C activity of rat liver cells. Toxicol. Appl. Pharmacol. 63, 216-299.
18. Lamb R. G., Snyder J. W., and Coleman J. B. (1988) New trends in the prevention of hepatocyte death: modifiers of calcium movement and of membrane phospholipid metabolism, in Liver Drugs from Experimental Pharmacology to Therapeutic Action (Testa B. and Perrissoud D., eds), pp. 53-66. CRC Press, Boca Raton, Florida.
19. Lamb R. G., Koch J. C., Snyder J. W., Huband S. M., and Bush S. R. (1994) An in vitro model of ethanol-dependent liver cell injury. Hepatology 19, 174-182.
20. Lowry O. H., Rosebrough N. J., Farr A. L., and Randall R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275.
21. McCord J. M. and Day E. D. (1978) Superoxide-dependent production of hydroxyl radical catalyzed by iron-EDTA complex. FEBS Lett. 86, 139-142.
22. McKinney J. S., Willoughby K. A., Liang S., and Ellis E. F. (1996) Stretch-induced injury of cultured neuronal, glial and endothelial cells. Stroke 27, 934-940.
23. Muizelaar J. P., Marmarou A., Young H. F., Choi S. C., Wolf A., Schneider R. L., and Kontos H. A. (1993) Improving the outcome of severe head injury with the oxygen radical scavenger polyethylene glycol-conjugated superoxide dismutase: a phase II trial. J. Neurosurg. 78, 375-382.
24. Reynolds E. S. and Molsen M. T. (1980) Environmental liver injury: halogenated hydrocarbons, in Toxic Injury of Liver (Farber E. and Fisher M. M., eds), pp. 541-596. Marcel Dekker, New York.
25. Rzigalanski B. A. and Rosenthal M. D. (1994) Effects of DMSO-induced differentiation on arachidonate mobilization in the human histiocytic lymphoma cell line U937: responsiveness to sub-micromolar calcium ionophore A23187 and phorbol esters. Biochim. Biophys. Acta 1223, 219-225.
26. 2. Biochim. Biophys. Acta 1042, 380-385.
27. Sen S., Goldman H., Morehead M., Murphy S., and Phillis J. W. (1994) α-Phenyl-tert-butyl-nitrone inhibits free radical release in brain concussion. Free Radic. Biol. Med. 16, 685-691.
28. 2 is activated after experimental closed head injury in the rat. J. Neurochem. 53, 1541-1546.
29. Siesjö B. K. (1993) Basic mechanisms of traumatic brain damage. Ann. Emerg. Med. 22, 959-969.
30. Spector A. A. and Yorek M. A. (1985) Membrane lipid composition and cellular function. J. Lipid Res. 26, 1015-1035.
31. Tavlin S. J., Ellis E. F., and Satin L. S. (1995) Mechanical perturbation of cultured cortical neurons reveals a stretch-induced delayed depolarization. J. Neurophysiol. 74, 2767-2773.
32. Wei E. P., Lamb R. G., and Kontos H. A. (1982) Increased phospholipase C activity after experimental brain injury. J. Neurosurg. 56, 695-698.
33. Weinhold P. A., Rounsifier M. E., and Feldman D. A. (1986) The purification and characterization of CTP:phosphorylcholine cytidylyltransferase from rat liver. J. Biol. Chem. 261, 5104-5111.
34. Wey H. E., Pyron L., and Woolery M. (1993) Essential fatty acid deficiency in cultured human keratinocytes attenuates toxicity due to lipid peroxidation. Toxicol. Appl. Pharmacol. 120, 72-79.
35. Whitl B. C. and Krause G. S. (1993) Brain injury and repair mechanisms: the rationale for pharmacologic therapy in closed-head trauma. Ann. Emerg. Med. 22, 970-979.
36. Yao Z., Jamil H., and Vance D. E. (1990) Choline deficiency causes translocation of CTP:phosphocholine cytidylyltransferase from cytosol to endoplasmic reticulum in rat liver. J. Biol. Chem. 265, 4326-4331.
37. Younes M. (1988) Free radical scavengers and antioxidants, in Liver Drugs from Experimental Pharmacology to Therapeutic Action (Testa B. and Perrisoud D., eds), pp. 31-52. CRC Press, Boca Raton, Florida.