A surface plasmon resonance biosensor for the determination of the affinity of drugs for nucleic acids

Analytical Letters

Volumn 35, Issue 4, 2002, Pages 599-613

  Tombelli, S ^a   Minunni, M ^a   Mascini, M ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Affinity; DNA biosensor; Drugs; Surface plasmon resonance

Indexed keywords

1,2 DIAMINOANTHRAQUINONE; 2 AMINOANTHRACENE; ACRIDINE ORANGE; ANTHRAQUINONE DERIVATIVE; DACTINOMYCIN; DAUNORUBICIN; DIETHYLSTILBESTROL; DNA; DOXORUBICIN; ETHIDIUM BROMIDE; NOGALAMYCIN; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BIOSENSOR; CALCULATION; CONTROLLED STUDY; DRUG DNA BINDING; GENE EXPRESSION REGULATION; GENOTOXICITY; INTERMETHOD COMPARISON; MEDICAL LITERATURE; MOLECULAR BIOLOGY; NONHUMAN; NUCLEIC ACID IMMOBILIZATION; POLLUTANT; SURFACE PLASMON RESONANCE; TOXICITY TESTING;

EID: 0036250095     PISSN: 00032719     EISSN: None     Source Type: Journal    
DOI: 10.1081/AL-120003164     Document Type: Article

References (17)

1. A review of the genotoxicity of marketed pharmaceuticals
2. New approaches to estimating the mutagenic potential of chemicals
3. Interpretation of the biological relevance of genotoxicity test results: The importance of thresholds
4. A surface plasmon resonance method for detecting multiple modes of DNA-ligand interactions
5. A strategy for the broad range detection of compounds with affinity for nucleic acids
6. Electrochemical DNA biosensor for environmental monitoring
7. Biospecific interaction analysis (BIA) of low-molecular weight DNA- binding drugs
8. Specific binding of low molecular weight ligands with direct optical detection
9. Adsorbed ω-hydroxy thiol monolayer on gold electrodes: Evidence for electron tunneling to redox species in solution
10. A DNA piezoelectric biosensor assay coupled with a polymerase chain reaction for bacterial toxicity determination in environmental samples
11. Structural studies of atom-specific anticancer drugs acting on DNA
12. Binding specificities of actinomycin D to self-complementary tetranucleotide sequences - XGCY-
13. Fluorescent energy transfer between acridine orange safranine T and its application in the determination of DNA
14. Criteria for the mode of binding of DNA binding agents
15. Adsorptive stripping potentiometry of DNA at electrochemically pretreated carbon paste electrodes
16. The mechanism of intercalation into the DNA double helix by ethidium
17. Risk assessment