Hydrogen peroxide-induced inhibition of vasomotor activity: Evaluation of single and combined treatments with vitamin A and insulin in streptozotocin-diabetic rats

International Journal of Experimental Diabetes Research

Volumn 3, Issue 2, 2002, Pages 119-130

  Zobali, Fulya ^a   Besler, Tanju ^b   Ari, Nuray ^a   Karasu, Çimen ^a  

^a ANKARA UNIVERSITY   (Turkey)

^b HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Hydrogen peroxide; Insulin; Peroxidative stress; Rat aorta; Retinol binding protein; STZ diabetes; Vasomotor activity; Vitamin A

Indexed keywords

ACETYLCHOLINE; GLUCOSE; HYDROGEN PEROXIDE; INSULIN; PHENYLEPHRINE; RETINOL ACETATE; RETINOL BINDING PROTEIN; STREPTOZOCIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ADRENERGIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA CONSTRICTION; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DIABETES MELLITUS; ENDOTHELIUM; GLUCOSE METABOLISM; GROWTH RATE; IN VITRO STUDY; MALE; METABOLIC REGULATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REVIEW; STREPTOZOCIN DIABETES; VASCULAR RING; VASOCONSTRICTION; VASODILATATION; VASOMOTOR REFLEX; VITAMIN METABOLISM;

ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC ANGIOPATHIES; DRINKING BEHAVIOR; DRUG THERAPY, COMBINATION; FEEDING BEHAVIOR; HYDROGEN PEROXIDE; HYPOGLYCEMIC AGENTS; INSULIN; LIPID PEROXIDATION; MALE; OXIDATIVE STRESS; PHENYLEPHRINE; RATS; RATS, WISTAR; THIOBARBITURIC ACID REACTIVE SUBSTANCES; VASOCONSTRICTION; VASOMOTOR SYSTEM; VITAMIN A;

EID: 0036249133     PISSN: 15604284     EISSN: None     Source Type: Journal    
DOI: 10.1080/15604280214484     Document Type: Review

References (44)

1. Glucose and diabetic vascular disease
2. Possible superoxide radical-induced alteration of vascular reactivity in aortas from streptozotocin-treated rats
3. Oxidative stress and diabetic vascular complications
4. Antioxidant and triglyceride lowering effects of vitamin E associated with the prevention of abnormalities in the reactivity and morphology of aorta from streptozotocin-diabetic rats
5. Changes in isoprenaline-induced endothelium-dependent and -independent relaxations of aorta in long-term STZ-diabetic rats: Reversal effect of dietary vitamin E
6. 2 in aorta isolated from chronically streptozotocin-diabetic rats: Effects of antioxidant enzymes and enzymes inhibitors
7. Time course of changes in endothelium-dependent and -independent relaxation of chronically diabetic aorta: Role of reactive oxygen species
8. The role of endothelial cells on the alterations in vascular reactivity induced by insulin-dependent diabetes mellitus: Effects of insulin treatment
9. Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; comparison with essential fatty acids
10. Acute Probucol treatment partially restores vasomotor activity and abnormal lipid metabolism whereas morphological changes are not affected in aorta from long-term STZ-diabetic rats
11. Alpha-lipoic acid treatment ameliorates metabolic parameters, blood pressure, vascular reactivity and morphology of vessels already damaged by streptozotocin-diabetes
12. Transport and metabolism of vitamin A
13. Contribution of vitamin A to the oxidation resistance of human low density lipoproteins
14. Vitamin A homeostasis and diabetes mellitus
15. Plasma retinol and alpha-tocopherol concentrations in insulin-dependent diabetes mellitus: Their relationship to microvascular complications
16. Streptozotocin-induced diabetes in rats is associated with impaired metabolic availability of vitamin A (retinol)
17. High retinol/retinol-binding protein ratio in noninsulin-dependent diabetes mellitus
18. Effects of dietary fats, alpha-tocopherol and beta-carotene supplementation on aortic ring segment responses in the rat
19. Dietary antioxidants preserve endothelium-dependent vessel relaxation in cholesterol-fed rabbits
20. Increased risk of cardiovascular disease at suboptimal plasma concentration of essencial antioxidants: An epidemiological update with special attention to carotene and vitamin C
21. Microzommal enzyme inducers and hypervitaminossis A in rats
22. Determination of vitamins A and E in serum and plasma using a simplified clarification method and high-performance liquid chromatography
23. Immunonephelometry and radial immunodiffusion compared for measuring serum retinol-binding protein
24. Elevated lipid peroxidation and vitamin E-quinone levels in heart ventricles of streptozotocin treated diabetic rats
25. Protein kinase C activation and the development of diabetic complications
26. 2+ release from vascular smooth muscle sarcoplasmic reticulum
27. The effect of insulin treatment on changes in vascular reactivity in chronic, experimental diabetes
28. Insulin induced reversibility of altered responsiveness in femoral arterial bed of diabetic dogs
29. Effects of diabetes and treatment with the antioxidant alpha-lipoic acid on endothelial and neurogenic responses of corpus cavernosum in rats
30. Insulin's effect on protein kinase C and diacylglycerol induced by diabetes and glucose in vascular tissues
31. 2+ sensitivity as a mechanism of hydrogen peroxide-induced relaxation of rabbit aorta
32. Hydrogen peroxide-induced impairment of reactivity in rat isolated aorta: Potentiation by 3-amino-1,2,4-triazole
33. Effects of hydrogen peroxide on pig coronery artery endothelium
34. Involvement of nitric oxide in the endothelium-dependent relaxation induced by hydrogen peroxide in the rabbit aorta
35. 2+ and other cellular metabolites
36. Oxidative stress augments secretion of endothelium-derived relaxing peptides, C-type natriuretic peptide and adrenomedulin
37. Activation of soluble guanylate cyclase from rat lung by incubation or by hydrogen peroxide
38. Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice
39. 2+ and proteolysis in lethal oxidative injury in endothelial cells
40. i of cultured rat arterial smooth muscle cells
41. Effect of vitamins A and E on ischemia-reperfusion damage in rabbit heart
42. The metabolic availability of vitamin A is decreased at the onset of diabetes in BB rats
43. Protective effects of retinyl palmitate on streptozotocin- and alloxan-induced beta cell toxicity and diabetes in the rat
44. Prophylactic effect of vitamin A, neutralizing the development of experimental insulin-dependent diabetes in animals