Time course of changes in endothelium-dependent and -independent relaxation of chronically diabetic aorta: Role of reactive oxygen species

European Journal of Pharmacology

Volumn 392, Issue 3, 2000, Pages 163-173

  Karasu, Çimen ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Aorta; Catalase; Endothelium dependent relaxation; Endothelium independent relaxation; Hydrogen peroxide; Nitric oxide (NO); Streptozotocin diabetes; Superoxide; Superoxide dismutase

Indexed keywords

ACETYLCHOLINE; AMITROLE; CATALASE; DEFEROXAMINE; DIETHYLDITHIOCARBAMIC ACID; MANNITOL; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ENDOTHELIUM; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; VASODILATATION;

ACETYLCHOLINE; AMITROLE; ANIMALS; AORTA, THORACIC; BLOOD GLUCOSE; BODY WEIGHT; CATALASE; CHRONIC DISEASE; DEFEROXAMINE; DIABETES MELLITUS, EXPERIMENTAL; DITIOCARB; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; FREE RADICAL SCAVENGERS; MALE; MANNITOL; NITROPRUSSIDE; PHENYLEPHRINE; RATS; SUPEROXIDE DISMUTASE; TIME FACTORS; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATION; VASODILATOR AGENTS;

EID: 0034737625     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00140-0     Document Type: Article

References (51)

1. Altan V.M., Karasu Ç., Özüari A. The effects of Type-1 and Type-2 diabetes on endothelium-dependent relaxation in rat aorta. Pharmacol., Biochem. Behav. 33:1989;519-522.
2. Bhardwaj R., Moore P.K. Increased vasodilator response to acetylcholine of renal blood vessels from diabetic rats. J. Pharm. Pharmacol. 40:1988;739-742.
3. Chang K.C., Chung S.Y., Chong W.S., Suh J.S., Kim S.H., Noh H.K., Seong B.W., Ko H.J., Chun K.W. Possible superoxide radical-induced alteration of vascular reactivity in aortas from streptozotocin-treated rats. J. Pharmacol. Exp. Ther. 266:1993;992-1000.
4. Cohen R.A., Vanhoutte P.M. Endothelium-dependent hyperpolarization. Beyond nitric oxide and cyclic GMP. Circulation. 92:1995;3337-3349.
5. Dai F.X., Diederich A., Scopec J., Diederich D. Diabetes-induced endothelial dysfunction in streptozotocin-treated rats: role of prostaglandin endoperoxides and free radicals. J. Am. Soc. Nephrol. 4:1993;1327-1336.
6. Diederich D., Scopec J., Diederich A., Dai F.X. Endothelial dysfunction in mesenteric resistance arteries of diabetic rat: role of free radicals. Am. J. Physiol. 266:1994;H1153-H1161.
7. Fraile M.L., Conde M.V., Sanz L., Moreno M.J., Marco E.J., Lopez de Pablo A.L. Different influence of superoxide anions and hydrogen peroxide on endothelial function of isolated cat cerebral and pulmonary arteries. Gen. Pharmacol. 25:1994;1197-1205.
8. 2+ and proteolysis in lethal oxidative injury in endothelial cells. Am. J. Pysiol. 261:1991;C889-C896.
9. Gryglewski R.J., Palmer R.M.J., Moncada S. Superoxide anion plays a role in the breakdown of endothelium-derived relaxing factor. Nature. 320:1986;454-456.
10. Hamon C.G., Culter P., Blair J.A. Tetrahydrobiopterin metabolism in the streptozotocin induced diabetic state in rats. Clin. Chim. Acta. 181:1989;249-254.
11. Hattori Y., Kawasaki H., Kazuhiro A., Kanno M. Superoxide dismutase recovers altered endothelium-dependent relaxation in diabetic rat aorta. Am. J. Physiol. 261:1991;H1086-H1094.
12. 2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase. Biochem. J. 281:1992;627-630.
13. Jain S.K., Levine S.N. Elevated lipid peroxidation and vitamin E-quinone levels in heart ventricles of streptozotocin treated diabetic rats. Free Radical Biol. Med. 18:1995;337-341.
14. Kamata K., Miyata N., Kasuya Y. Impairment of endothelium-dependent relaxation and changes on levels of cyclic GMP in aorta from streptozotocin-induced diabetic rats. Br. J. Pharmacol. 97:1989;614-618.
15. 2 in aorta isolated from chronically streptozotocin-diabetic rats: effects of antioxidant enzymes and enzyme inhibitors. Free Radical Biol. Med. 27:1999;16-27.
16. Karasu Ç., Altan V.M. The role of the endothelium on enhanced contractile response of non-insulin-dependent diabetic rat aortae: effects of insulin treatment. Gen. Pharmacol. 25:1994;795-802.
17. Karasu Ç., Ozansoy G., Bozkurt O., Erdogan D., Ömeroglu S. Antioxidant and triglyceride lowering effects of vitamin E associated with the prevention of abnormalities in the reactivity and morphology of aorta from streptozotocin-diabetic rats. Metabolism. 46:1997;872-879.
18. Karasu Ç., Ozansoy G., Bozkurt O., Erdogan D., Ömeroglu S. Changes in isoprenaline-induced endothelium-dependent and -independent relaxations of aorta in long-term STZ-diabetic rats: Reversal effect of dietary vitamin E. Gen. Pharmacol. 29:1997;561-567.
19. Kenato H., Fujii J., Duzuki K., Kawamori R., Kamata T., Taniguchi N. DNA cleavage induced by glycation of Cu,Zn-superoxide dismutase. Biochem. J. 304:1994;219-225.
20. 2+]i of cultured rat arterial smooth muscle cells. Biochem. Biophys. Res. Commun. 209:1995;139-145.
21. Langenstroer P., Pieper G.M. Regulation of spontaneous EDRF release in diabetic rat aorta by oxygen free radicals. Am. J. Physiol. 263:1992;H257-H265.
22. Lyons T.J. Lipoprotein glycation and its metabolic consequences. Diabetes. 41(Suppl. 2):1992;67-73.
23. Margoliash E., Novogrodsky A. A study of the inhibition of catalase by 3-amino-1,2,4-triazole. Biochem. J. 68:1958;468-475.
24. Mian K.B., Martin W. Differential sensitivity of basal and acetylcholine-stimulated activity of nitric oxide to destruction by superoxide anion in rat aorta. Br. J. Pharmacol. 15:1995;993-1000.
25. Mian K.B., Martin W. The inhibitory effect of 3-amino-1,2,4-triazole on relaxation induced by hydroxylamine and sodium azide but not hydrogen peroxide of glyceryl trinitrate in rat aorta. Br. J. Pharmacol. 116:1995;3302-3308.
26. Mian K.B., Martin W. Hydrogen peroxide-induced impairment of reactivity in rat isolated aorta:potentiation by 3-amino-1,2,4-triazole. Br. J. Pharmacol. 121:1997;813-819.
27. 2-associated relaxation. Am. J. Physiol. 271:1996;H1900-H1906.
28. Mügge A., Elwell J.H., Peterson T.E., Harrison D.G. Release of intact endothelium-derived relaxing factor depends on endothelial superoxide dismutase activity. Am. J. Physiol. 260:1991;C219-C225.
29. Oberly L.W., Spitz D.R. Nitroblue tetrozolium. Greenwald R.A. Handbook of Methods for Oxygen Radical Research. 1985;217-220 CRC, Boca Raton, FL.
30. Ohkuwa T., Sato Y., Naoi M. Hydroxyl radical formation in diabetic rats induced by streptozotocin. Life Sci. 56:1995;1789-1798.
31. Omar H.A., Cherry P.D., Mortelliti P.M., Burke-Wolin T., Wolin M.S. Inhibition of coronary artery superoxide dismutase attenuates endothelium-dependent and -independent nitrovasodilator relaxation. Circ. Res. 69:1991;601-608.
32. Oyama Y., Kawasaki H., Hattori Y., Kanno M. Attenuation of endothelium-dependent relaxation in aorta from diabetic rats. Eur. J. Pharmacol. 131:1986;75-78.
33. Palmer R.M., Ashton D.S., Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature. 333:1988;664-666.
34. Pieper G.M. Oxidative stress in diabetic blood vessels. FASEB J. 9:1995;A98.1. (Abstract).
35. Pieper G.M. Acute amelioration of diabetic endothelial dysfunction with a derivative of nitric oxide synthase cofactor, tetrahydrobiopterin. J. Cardiovasc. Pharmacol. 29:1997;8-15.
36. Pieper G.M. Review of alterations in endothelial nitric oxide production in diabetes. Protective role of arginine on endothelial dysfunction. Hypertension. 31:1998;1047-1060.
37. Pieper G.M. Enhanced, unaltered and impaired nitric oxide-mediated endothelium-dependent relaxation in experimental diabetes mellitus: importance of disease duration. Diabetologia. 42:1999;204-213.
38. Pieper G.M., Dodlinger L.A. Extracellular and intracellular arginine deficiency in diabetes leads to reduced endothelium-dependent relaxation and cGMP generation. Circulation. 9(Suppl. I):1996;1-703.
39. Pieper G.M., Gross G.J. Oxygen free radicals abolish endothelium-dependent relaxation in diabetic aorta. Am. J. Physiol. 255:1988;H825-H833.
40. Pieper G.M., Langenstroer P., Siebeneich W. Diabetic-induced endothelial dysfunction in rat aorta: role of hydroxyl radicals. Cardiovasc. Res. 34:1997;145-156.
41. Pieper G.M., Mei D.A., Langenstroer P., O'Rourke S.T. Bioassay of endothelium-derived relaxing factor in diabetic rat aorta. Am. J. Physiol. 263:1992;H676-H680.
42. Pieper G.M., Siebeneich W. Diabetes-induced endothelial dysfunction is prevented by long-term treatment with the modified iron chelator, hydroxyethyl starch conjugated-desferoxamine. J. Cardiovasc. Pharmacol. 30:1997;734-738.
43. Pieper G.M., Siebeneich W. Use of a nitronyl nitroxide to discriminate the contribution of nitric oxide radical in endothelium-dependent relaxation of control and diabetic blood vessels. J. Pharmacol. Exp. Ther. 282:1997;138-147.
44. Pugliese G., Tilton G.R., Williamson J.R. Glucose-induced metabolic imbalances in the pathogenesis of diabetic vascular disease. Diabetes Metab. Rev. 7:1991;35-59.
45. Rubanyi G.M., Vanhoutte P.M. Modulation of the release and biological activity of endothelium-derived relaxing factor by oxygen-derived free radicals. Vanhoutte P.M. Relaxing and Contracting Factors. 1988;91-105 Humana Press, Clifton, NJ.
46. Satoh K. Serum lipid peroxides in cerebrovascular disorders determined by a new colorimetric method. Clin. Chim. Acta. 90:1978;37-43.
47. Taniguchi N., Kaneto H., Ashi M., Takagashi M., Wenyi C., Higashiyama S., Fujii J., Suzuki K., Kayanoki Y. Involvement of glycation and oxidative stress in diabetic macroangiopathy. Diabetes. 45(Suppl. 3):1996;S81-S83.
48. Tesfamariam B., Cohen R.A. Free radicals mediate endothelial cell dysfunction caused by elevated glucose. Am. J. Physiol. 263:1992;H321-H326.
49. Wakabayashi I., Hatake K., Kimura N., Kakishita E., Nagai K. Modulation of vascular tonus by the endothelium in experimental diabetes. Life Sci. 40:1987;643-648.
50. White R.E., Carrier G.O. Supersensitivity and endothelium-dependency of histamine-induced relaxation in mesenteric arteries isolated from diabetic rats. Pharmacology. 33:1986;34-38.
51. Zembowicz A., Hatchett R.J., Jakubowski A.M., Grylewski R.J. Involvement of nitric oxide in the endothelium-dependent relaxation induced by hydrogen peroxide in the rabbit aorta. Br. J. Pharmacol. 110:1993;151-158.