Effectiveness and tolerability of ibuprofen-arginine versus paracetamol in children with fever of likely infectious origin

Acta Paediatrica, International Journal of Paediatrics

Volumn 91, Issue 4, 2002, Pages 383-390

  Figueras Nadal, C ^a   Garcia de Miguel M J ^a   Gomez Campdera A ^a   Pou Fernandez J ^a   Alvarez Calatayud, G ^a   Sanchez Bayle M ^a   Figueras, C ^a   Bertran, J M ^a   Boronat, M ^a   Garcia L ^a   Irastorza, I ^a   Garcia M J ^a   De Jose M I ^a   Borgue, C ^a   Del Castillo, F ^a   Baquero, F ^a   Gomez J A ^a   Navarro, M L ^a   Rodrigez R M ^a   Gonzalez M I ^a   Pou, J ^a   Luaces, C ^a   Garcia J J ^a   Fernandez Y ^a   Alvarez G ^a   Canete A ^a   Claver, E ^a   Rivas, A ^a   Urribari, F ^a   Pinel, G ^a   Taboada, L ^a   Sanchez M ^a   Branas P ^a   Molina, J C ^a   Sanz, L ^a   De Vicente, A ^a   Gonzalez M ^a   Ruiz, C ^a   Palacios, M ^a   Guerrero, R ^a   more..

^a HOSPITAL MATERNO INFANTIL VALL D HEBRON   (Spain)

Author keywords

Fever; Ibuprofen arginine; Infectious disease; Nitric oxide; Paracetamol

Indexed keywords

IBUPROFEN ARGININE; PARACETAMOL; PLACEBO;

ABDOMINAL PAIN; ARTICLE; BODY TEMPERATURE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG FORMULATION; DRUG TOLERABILITY; FEMALE; FEVER; HEMATEMESIS; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; NEUTROPENIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; VOMITING;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ARGININE; CHILD; CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; ENDPOINT DETERMINATION; FEMALE; FEVER; HUMANS; IBUPROFEN; MALE;

EID: 0036245302     PISSN: 08035253     EISSN: None     Source Type: Journal    
DOI: 10.1080/080352502317371607     Document Type: Article

References (27)

1. Reye's syndrome and aspirin
2. Treatment of fever in childhood
3. Fever in infants and children
4. Paracetamol poisoning in children and hepatotoxicity
5. Antipyretic activity of ibuprofen and paracetamol in children with pyrexia
6. Clinical pharmacology of paediatric antipyretic drugs
7. Ibuprofen suspension: Pediatric antipyretic
8. A dose ranging study of ibuprofen suspension as an antipyretic
9. Comparative efficacy and tolerance of ibuprofen syrup and acetaminophen syrup in children with pyrexia associated with infectious diseases and treated with antibiotics
10. Toxicity of NSAIDs in the stomach and duodenum
11. Nitrovasodilators, low-dose aspirin, other nonsteroidal antiinflammatory drugs, and the risk of upper gastrointestinal bleeding
12. Nitric oxide: A regulator of mucosal defense and injury
13. Role of nitric oxide in the gastric cytoprotection induced by central vagal stimulation
14. Endogenous nitric oxide modulates ethanol-induced gastric mucosal injury in rats
15. Nitric oxide activates cyclooxygenase enzymes
16. Role of L-arginine, a substrate for nitric oxide-synthase, in gastroprotection and ulcer healing
17. Protective effect of L-arinine against ibuprofen induced gastric injury in rats
18. Experimental gastric mucosal injury induced by different NSAID COX1/COX2 inhibitors and protective action of L-arginine
19. L-arginine blunts the impairment in gastric mucosal blood flow and mucus secretion induced by ibuprofen
20. Activity and pharmacokinetics of a new oral dosage form of soluble ibuprofen
21. Determination of normal ear temperature with an infrared emission detection thermometer
22. Assessment of the efficacy and safety of paracetamol, ibuprofen and nimesulide in children with upper respiratory tract infections
23. Ibuprofen, acetaminophen, and placebo treatment of febrile children
24. Antipyretic efficacy of ibuprofen vs acetaminophen
25. Equivalent antipyretic activity of ibuprofen and paracetamol in febrile children