Evaluation of UV-radiation induced singlet oxygen generation potential of selected drugs

Drug and Chemical Toxicology

Volumn 25, Issue 2, 2002, Pages 215-225

  Pandey, R ^a   Mehrotra, S ^a   Ray, R S ^a   Joshi, P C ^a   Hans, R K ^a  

^a Dr RML Avadh University   (India)

Author keywords

Drugs; Quenchers; Singlet oxygen; Ultraviolet radiation

Indexed keywords

1,4 DIAZABICYCLO[2.2.2]OCTANE; AMPHOTERICIN B; AMPICILLIN; ANTIBIOTIC AGENT; BETA CAROTENE; CEFALEXIN; CEFALOTIN; CEFAZOLIN; CEFRADINE; GENTAMICIN; KANAMYCIN; LINCOMYCIN; NAFCILLIN; NALIDIXIC ACID; NYSTATIN; PUROMYCIN; REACTIVE OXYGEN METABOLITE; SINGLET OXYGEN; SODIUM AZIDE; TETRACYCLINE;

ARTICLE; BIOSYNTHESIS; DRUG SCREENING; OXIDATIVE STRESS; PHOTOSENSITIZATION; PHOTOTOXICITY; REACTION ANALYSIS; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION;

ANTI-BACTERIAL AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; PHOTOCHEMISTRY; SINGLET OXYGEN; ULTRAVIOLET RAYS;

EID: 0036245253     PISSN: 01480545     EISSN: None     Source Type: Journal    
DOI: 10.1081/DCT-120003261     Document Type: Article

References (45)

1. The two major spore DNA repair pathways, nucleotide excision repair and spore photoproduct lyase, are sufficient for the resistance of bacillus subtilis spores to artificial UVC and UVB but not in solar radiation
2. Protection against peroxynitrite dependent tyrosine nitration and alpha 1-antiproteinase inactivation by some anti-inflammatory drugs and by the antibiotic tetracycline
3. Photosensitized reactions of DNA: Cleavage and addition
4. Drug induced photosensitivity (phototoxic and photoallergic drug reactions)
5. -) by psoralens and UVR (320-400 nm)
6. UVR induced production of superoxide radicals by selected antibiotics
7. Effect of pyridone carboxylic acid antimicrobials on the generation of reactive oxygen species in vitro
8. Drug induced photosensitivity (phototoxic and photoallergic drug reactions)
9. Photoirritation (phototoxicity, phototoxic dermatitis)
10. Evaluation of UV-induced superoxide radical generation potential of some common antibiotics
11. Antioxidant, OPC-14117, attenuated edema formation and behavioral deficit following cortical contusion in rats
12. Generation of ROS by the redox cycling of nitropruside
13. Unambiguous evidence for the participation of singlet oxygen in photodynamic oxidation of amino acids
14. New method of detecting singlet oxygen production
15. A new method for the detection of singlet oxygen in aqueous solution
16. Determination of the lifetime of singlet oxygen in D20 using 9,10-Anthracenedipropionic acid, a water soluble probe
17. 2 by phyco-biliproteins in neutral aqueous solution
18. 2-production by riboflavin, lumichrome and lumiflavin
19. Photosensitization by drugs: Nalidixic and oxolinic acids
20. Mechanism of tetracycline phototoxicity
21. Superoxide radical photogenerated from aqueous solutions of tetracycline antibiotics (pH 7.3) as evidenced by DMPO spin trapping and cytochrome-c reduction
22. Free radicals as mediators of tissue injury and disease
23. Photosensitized degradation of DNA by daunomycin
24. Fluoroquinolene antibacterials enhance UVA-induced skin tumors
25. Comparison of an in vivo cellular phototoxicity model against controlled clinical trials of fluoroquinolene skin phototoxicity
26. Reactive oxygen generation by azomethine-h: A new antimalarial drug
27. The exogenous NADH dehydrogenase of heart mitochondria is the key enzyme responsible for selective cardiotoxicity of anthracyclines
28. Recent advances in research on SMANCS
29. Light dependent generation of ROS in cell culture media
30. Quenching of 102 by tertiary aliphatic amines, effects of DABCO
31. Chemistry of singlet oxygen. XV. Irrelevance of azide trapping to mechanism of the ene reaction
32. 2 during ischemia and reperfusion in rat hearts
33. 2 oxidation products of β-carotene
34. The role of active oxygen (102 and 02) induced by crude coal tar and its ingrediant used in photochemotherapy of skin diseases
35. Photosensitizing potential of benzanthrone
36. Molecular aspects of drug photosensitivity with special emphasis on psoralen sensitization reactions
37. Photosensitization of skin in vivo by furocoumarins (psoralens)
38. Quantum yield of singlet oxygen production by monomeric and aggregated forms of hematoporphyrin derivative
39. Comparison of the DNA-damaging property of photosensitized riboflavin via singlet oxygen and superoxide mechanisms
40. Riboflavin photosensitized hemolysis of rat erythrocytes in the presence of serum
41. Cross-linking of lens crystallins in a photodynamic system: A process mediated by singlet oxygen