Comparison of an in vitro cellular phototoxicity model against controlled clinical trials of fluoroquinolone skin phototoxicity

Toxicology in Vitro

Volumn 14, Issue 3, 2000, Pages 275-283

  Traynor, N J ^a   Barratt, M D ^b   Lovell, W W ^c   Ferguson, J ^a   Gibbs, N K ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b Marlin Consultancy   (United Kingdom)

^c UNILEVER RESEARCH   (United Kingdom)

Author keywords

Clinical; Fluoroquinolone; In vitro; MTT; Neutral red; Phototesting; Phototoxocity

Indexed keywords

8 CHLORO 1 CYCLOPROPYL 7 (2,8 DIAZABICYCLO[4.3.0]NON 8 YL) 6 FLUORO 1,4 DIHYDRO 4 OXO 3 QUINOLINECARBOXYLIC ACID; CIPROFLOXACIN; GREPAFLOXACIN; LOMEFLOXACIN; MOXIFLOXACIN; NALIDIXIC ACID; NORFLOXACIN; OFLOXACIN; PLACEBO; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TROVAFLOXACIN;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL VIABILITY; CHINESE HAMSTER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOTOXICITY; DOUBLE BLIND PROCEDURE; ERYTHEMA; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; LUNG FIBROBLAST; NONHUMAN; NORMAL HUMAN; PHOTOSENSITIZATION; PHOTOTOXICITY; PRINCIPAL COMPONENT ANALYSIS; REGRESSION ANALYSIS; SKIN TOXICITY; ULTRAVIOLET A RADIATION;

ANIMALS; ANTI-INFECTIVE AGENTS; CELLS, CULTURED; CRICETINAE; CRICETULUS; DERMATITIS, PHOTOTOXIC; DOUBLE-BLIND METHOD; FLUOROQUINOLONES; HUMANS;

CRICETINAE; CRICETULUS GRISEUS;

EID: 0034055670     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(00)00017-5     Document Type: Article

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