Identification of two novel elements involved in human MUC1 gene expression in vivo

Molecular Medicine

Volumn 8, Issue 1, 2002, Pages 33-41

  Shiraga, Toshiyuki ^a   Smith, David ^a   Nuthall, Hugh N ^a   Hollingsworth, Michael A ^a   Harris, Ann ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE I; MUCIN 1;

ARTICLE; CANCER CELL CULTURE; CELL TYPE; CHROMATIN; COLON ADENOMA; COLON CARCINOMA; CONTROLLED STUDY; GENE EXPRESSION; GENE MAPPING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HYPERSENSITIVITY; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; TRANSGENIC MOUSE;

EID: 0036243078     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03402001     Document Type: Article

References (28)

1. O-glycosylation of the mucin type
2. Characterization of cis-acting elements regulating transcription of the human DF3 breast carcinoma-associated antigen (MUC1) gene
3. Analysis of the tissue-specific promoter of the MUC1 gene
4. Transcriptional regulation of the MUC1 mucin gene in colon carcinoma cells by a soluble factor. Identification of a regulatory element
5. Soluble factor in normal tissues that stimulates high-molecular-weight sialoglycoprotein production by human colon carcinoma cells
6. The Sp1 transcription factor regulates cell type-specific transcription of MUC1
7. Studies of Muc-1 mucin expression and polarity in the mouse mammary gland demonstrate developmental regulation of Muc-1 glycosylation and establish the hormonal basis for mRNA expression
8. A stat-responsive element in the promoter of the episialin/MUC1 gene is involved in its overexpression in carcinoma cells
9. Regulation of MUC1 expression in human mammary cell lines by the c-ErbB2 and ras signaling pathways
10. Neoplastic transformation of a human colonic epithelial cell line: In vitro evidence for the adenoma to carcinoma sequence
11. Tissue-specific expression of a human polymorphic epithelial mucin (MUC1) in transgenic mice
12. Tolerance and immunity to MUC1 in a human MUC1 transgenic murine model
13. Characterization of clones of a human pancreatic adenocarcinoma cell line representing different stages of differentiation
14. Absence of HeLa cell contamination in 169 cell lines derived from human tumors
15. Absorptive and mucus-secreting subclones isolated from a multipotent intestinal cell line (HT-29) provide new models for cell polarity and terminal differentiation
16. A human cell line from a pleural effusion derived from a breast carcinoma
17. A regulatory element in intron 1 of the cystic fibrosis transmembrane conductance regulator gene
18. In vivo analysis of DNase I hypersensitive sites in the human CFTR gene
19. Tissue-specific DNase I hypersensitive sites in the 5′-flanking sequences of the tryptophan oxygenase and the tyrosine aminotransferase genes
20. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
21. Expression of the cystic fibrosis gene and the major pancreatic mucin gene MUC1 in human ductal epithelial cells
22. A major positive regulatory region located far upstream of the human alpha-globin gene locus
23. Mucin gene expression in colonic tissues and cell lines
24. Expression of MUC1 MUC2 MUC3 and MUC4 mucin mRNAs in human pancreatic and intestinal tumor cell lines
25. O-glycan biosynthesis in human colorectal adenoma cells during progression to cancer
26. A nuclear factor that binds purine-rich single-stranded oligonucleotides derived from S1-sensitive elements upstream of the CFTR gene and the MUC1 gene
27. Potential for H-DNA in the Human MUC1 mucin gene promoter
28. A potential H-DNA element in the MUC1 promoter does not influence transcription