Interaction of different doses of aspartame with morphine-induced antinociception in the presence of MK-801 a NMDA antagonist

Daru

Volumn 10, Issue 1, 2002, Pages 9-16

  Abdollahi, Mohammad ^a   Aghabarati, Fatemeh ^a   Nikfar, Shekoufeh ^a   Etemad, Forouzan ^a   Abdoli, Narges ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Antinociception; Aspartame; Formalin test; Morphine; NMDA; Sweetening agents

Indexed keywords

ASPARTAME; DIZOCILPINE; FORMALDEHYDE; MORPHINE SULFATE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NALOXONE; SWEETENING AGENT;

ANALGESIA; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; FOOD DRUG INTERACTION; MALE; MOUSE; NOCICEPTION; NONHUMAN; PAIN; SWEETNESS; TASTE;

EID: 0036237757     PISSN: 15608115     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Influence of intake of sweet solutions on the analgesic effect of low dose morphine in randomly bred rats
2. Interactions between sucrose, pain and isolation distress
3. Duration of sucrose availability differentially alters morphine analgesia in rats
4. Responsivity to pain in rats changed by the ingestion of flavored water
5. Dietary influences on morphine induced analgesia in rats
6. Effects of sweetening agents on morphine induced analgesia in mice by formalin test
7. Early onset of reduced morphine analgesia by ingestion of sweet solutions
8. Beyond sweet taste: Saccharin, sucrose, and polycose differ in their effects upon morphine induced analgesia
9. Diet and estrous cycle influence pain sensitivity in rats
10. Continuous sucrose feeding decreases pain threshold and increases morphine potency
11. Interaction between calcium channel blockers and sweetening agents on morphine induced analgesia in mice by formalin-test
12. 3H) glutamate transport in glial cultures
13. Effect of aspartate and glutamate on nociception, catalepsy and core temperature in rats
14. Morphine analgesia in the tail flick and formalin pain test is mediated by different neural systems
15. Methodological refinements to the mouse paw formalin test: An animal model of tonic pain
16. A role of periaqueductal gray NMDA receptors in mediating formalin induced pain in the rat
17. Intrathecal NMDA activates both nociceptive and antinociceptive systems
18. Comparative metabolism of aspartame in experimental animals and humans
19. Spinal nitric oxide synthesis inhibition blocks NMDA-induced thermal hyperalgesia and produces antinociception in the formalin test in rats
20. Lead-induced changes in NMDA receptor complex binding: Correlation with learning accuracy and with sensitivity to learning impairments caused by MK-801 and NMDA administration
21. The formalin test: A quantitative study of the analgesic effect of morphine, meperidine and brain stem stimulation in rats and cats
22. Formalin test in mice, a useful technique for evaluating mild analgesics
23. The formalin test in mice: Effect of formalin concentration
24. Subcutaneous formalin induced activity of dorsal horn neurons in the rat: Differential responses to an intrathecal opiate administered pre or post formalin
25. Activation of hypothalamic beta-endorphin pools by reward induced by highly palatable food
26. Prenatal exposure to morphine alters analgesic responses and preference for sweet solutions in adult rats
27. Effects of chronically elevated intake of different concentrations of saccharin on morphine tolerance in genetically selected rats
28. Morphine tolerance in genetically selected rats induced by chronically elevated saccharin intake
29. Treatment of osteoartritis with aspartame
30. Excitatory aminoacid receptors and nociceptive neurotransmission in rat spinal cord
31. Neurotransmitter candidates of somatosensory primary afferent fibers
32. Extracellular aminoacid concentrations in the dorsal spinal cord of freely moving rats following veratridine and nociceptive stimulation
33. The contribution of excitatory aminoacids to central sensitization and persistent nociception after formalin-induced tissue injury
34. NMDA receptor antagonists, MK-801 and ACEA-1011, prevent the development of tonic pain following subcutaneous formalin
35. The acute inflammatory reaction
36. Analgesic effects of several calcium channel blockers in mice
37. Effects of calcium channel blockers on formalin-induced nociception and inflammation in rats
38. Metal ion interactions with opiates
39. NMDA receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurons
40. Contribution of central neuroplasticity to pathological pain: Review of clinical and experimental evidence
41. Systemic opioids do not suppress spinal sensitization after subcutaneous formalin in rats
42. Nitric oxide (NO) and nociceptive processing in the spinal cord
43. Intraction between lead acetate and morphine on antinociception in mice by formalin test
44. Centrally administered opioid peptides stimulate saccharin intake in nondeprived rats