메뉴 건너뛰기




Volumn 85, Issue 2, 1997, Pages 161-174

Lead-induced changes in NMDA receptor complex binding: Correlations with learning accuracy and with sensitivity to learning impairments caused by MK-801 and NMDA administration

Author keywords

CGP 39653; Cognition; Lead; Learning; MK 801; N Methyl D aspartate (NMDA) receptor complex

Indexed keywords

2 AMINO 4 PHOSPHONOMETHYL 3 HEPTENOIC ACID; DIZOCILPINE; LEAD; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; RADIOLIGAND;

EID: 0030939009     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-4328(96)00174-X     Document Type: Article
Times cited : (44)

References (59)
  • 1
    • 0025125719 scopus 로고
    • Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead
    • Alkondon, M., Costa, A.C.S., Radhakrishnan, V., Aronstam, R.S. and Albuquerque, E.X., Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead, FEBS Lett., 261 (1990) 124-130.
    • (1990) FEBS Lett. , vol.261 , pp. 124-130
    • Alkondon, M.1    Costa, A.C.S.2    Radhakrishnan, V.3    Aronstam, R.S.4    Albuquerque, E.X.5
  • 2
    • 0025780658 scopus 로고
    • Long term potentiation in rat hippocampal slices is impaired following acute lead perfusion
    • Altmann, L., Sveinsson, K. and Wiegand, H., Long term potentiation in rat hippocampal slices is impaired following acute lead perfusion, Neurosci. Lett, 128 (1991) 109-112.
    • (1991) Neurosci. Lett , vol.128 , pp. 109-112
    • Altmann, L.1    Sveinsson, K.2    Wiegand, H.3
  • 5
    • 0030056351 scopus 로고    scopus 로고
    • Cholinergic denervation-like changes in rat hippocampus following developmental lead exposure
    • Bielarczyk, H., Tian, X. and Suszkiw, J.B., Cholinergic denervation-like changes in rat hippocampus following developmental lead exposure, Brain Res., 708 (1996) 108-115.
    • (1996) Brain Res. , vol.708 , pp. 108-115
    • Bielarczyk, H.1    Tian, X.2    Suszkiw, J.B.3
  • 6
    • 0028347624 scopus 로고
    • Perinatal low-level lead exposure and the septo-hippocampal cholinergic system: Selective reduction of muscarinic receptors and cholineacetyltransferase in the rat septum
    • Bielarczyk, H., Tomsig, J.L. and Suszkiw, J.B., Perinatal low-level lead exposure and the septo-hippocampal cholinergic system: selective reduction of muscarinic receptors and cholineacetyltransferase in the rat septum, Brain Res., 643 (1994) 211-217.
    • (1994) Brain Res. , vol.643 , pp. 211-217
    • Bielarczyk, H.1    Tomsig, J.L.2    Suszkiw, J.B.3
  • 7
    • 0029001708 scopus 로고
    • Different binding affinities of NMDA receptor channel blockers in various brain regions - Indication of NMDA receptor heterogeneity
    • Bresink, I., Danysz, W., Parsons, C.G. and Mutschler, E., Different binding affinities of NMDA receptor channel blockers in various brain regions - indication of NMDA receptor heterogeneity, Neuropharmacology, 34 (1995) 533-540.
    • (1995) Neuropharmacology , vol.34 , pp. 533-540
    • Bresink, I.1    Danysz, W.2    Parsons, C.G.3    Mutschler, E.4
  • 9
    • 0027991388 scopus 로고
    • The molecular basis of NMDA receptor subtypes: Native receptor diversity is predicted by subunit composition
    • Buller, A.L., Larson, H.C., Schneider, B.E., Beaton, J.A., Morrisett, R.A. and Monoghan, D.T., The molecular basis of NMDA receptor subtypes: native receptor diversity is predicted by subunit composition, J. Neurosci., 14 (1994) 5471-5484.
    • (1994) J. Neurosci. , vol.14 , pp. 5471-5484
    • Buller, A.L.1    Larson, H.C.2    Schneider, B.E.3    Beaton, J.A.4    Morrisett, R.A.5    Monoghan, D.T.6
  • 10
    • 0018420874 scopus 로고
    • Reversal learning deficits in young monkeys exposed to lead
    • Bushnell, P.J. and Bowman, R.E., Reversal learning deficits in young monkeys exposed to lead, Pharmacol. Biochem. Behav., 10 (1979) 733-742.
    • (1979) Pharmacol. Biochem. Behav. , vol.10 , pp. 733-742
    • Bushnell, P.J.1    Bowman, R.E.2
  • 11
    • 0001648919 scopus 로고
    • Late effects of lead poisoning on mental development
    • Byers, R. and Lord, E., Late effects of lead poisoning on mental development, Am. J. Dis. Child., 66 (1943) 471-494.
    • (1943) Am. J. Dis. Child. , vol.66 , pp. 471-494
    • Byers, R.1    Lord, E.2
  • 13
    • 0027492258 scopus 로고
    • Subsensitivity of lead-exposed rats to the accuracy-impairing and rate-altering effects of MK-801 on a multiple schedule of repeated learning and performance
    • Conn, J. and Cory-Slechta, D.A., Subsensitivity of lead-exposed rats to the accuracy-impairing and rate-altering effects of MK-801 on a multiple schedule of repeated learning and performance, Brain Res., 600 (1993) 208-218.
    • (1993) Brain Res. , vol.600 , pp. 208-218
    • Conn, J.1    Cory-Slechta, D.A.2
  • 14
    • 0028059624 scopus 로고
    • Lead exposure potentiates the effects of N-methyl-D-aspartate on repeated learning
    • Cohn, J. and Cory-Slechta, D.A., Lead exposure potentiates the effects of N-methyl-D-aspartate on repeated learning, Neurotoxicol. Teratol., 16 (1994) 455-466.
    • (1994) Neurotoxicol. Teratol. , vol.16 , pp. 455-466
    • Cohn, J.1    Cory-Slechta, D.A.2
  • 15
    • 0028598163 scopus 로고
    • Assessment of the role of dopamine systems in lead-induced learning impairments using a repeated acquisition and performance baseline
    • Cohn, J. and Cory-Slechta, D.A., Assessment of the role of dopamine systems in lead-induced learning impairments using a repeated acquisition and performance baseline, Neurotoxicology, 15 (1994) 913-926.
    • (1994) Neurotoxicology , vol.15 , pp. 913-926
    • Cohn, J.1    Cory-Slechta, D.A.2
  • 16
    • 0027384653 scopus 로고
    • The effects of lead exposure on learning in a multiple schedule of repeated acquisition and performance
    • Cohn, J., Cox, C. and Cory-Slechta, D.A., The effects of lead exposure on learning in a multiple schedule of repeated acquisition and performance, Neurotoxicology, 14 (1993) 329-346.
    • (1993) Neurotoxicology , vol.14 , pp. 329-346
    • Cohn, J.1    Cox, C.2    Cory-Slechta, D.A.3
  • 17
    • 0028610256 scopus 로고
    • The impact of NMDA receptor antagonists on learning and memory functions
    • Cory-Slechta, D.A., The impact of NMDA receptor antagonists on learning and memory functions, Psychopharmacol. Bull., 30 (1994) 601-612.
    • (1994) Psychopharmacol. Bull. , vol.30 , pp. 601-612
    • Cory-Slechta, D.A.1
  • 18
    • 0028986972 scopus 로고
    • MK-801 subsensitivity following postweaning lead exposure
    • Cory-Slechta, D.A., MK-801 subsensitivity following postweaning lead exposure, Neurotoxicology, 16 (1995) 85-96.
    • (1995) Neurotoxicology , vol.16 , pp. 85-96
    • Cory-Slechta, D.A.1
  • 19
    • 0028987874 scopus 로고
    • Relationships between lead-induced learning impairments and changes in dopaminergic, cholinergic and glutamatergic neurotransmitter system functions
    • Cory-Slechta, D.A., Relationships between lead-induced learning impairments and changes in dopaminergic, cholinergic and glutamatergic neurotransmitter system functions, Annu. Rev. Pharmacol. Toxicol., 35 (1995) 391-415.
    • (1995) Annu. Rev. Pharmacol. Toxicol. , vol.35 , pp. 391-415
    • Cory-Slechta, D.A.1
  • 20
    • 0029784996 scopus 로고    scopus 로고
    • Postweaning lead exposure enhances the stimulus properties of N-methyl-D-aspartate: Possible dopaminergic involvement?
    • Cory-Slechta, D.A., Pokora, M.J. and Johnson, J.L., Postweaning lead exposure enhances the stimulus properties of N-methyl-D-aspartate: possible dopaminergic involvement? Neurotoxicology, 17 (1996) 509-522.
    • (1996) Neurotoxicology , vol.17 , pp. 509-522
    • Cory-Slechta, D.A.1    Pokora, M.J.2    Johnson, J.L.3
  • 21
    • 0023608671 scopus 로고
    • Mobilization and redistribution of lead over the course of calcium disodium ethylenediamine tetracetate chelation therapy
    • Cory-Slechta, D.A., Weiss, B. and Cox, C., Mobilization and redistribution of lead over the course of calcium disodium ethylenediamine tetracetate chelation therapy, J. Pharmacol. Exp. Ther., 243 (1987) 804-813.
    • (1987) J. Pharmacol. Exp. Ther. , vol.243 , pp. 804-813
    • Cory-Slechta, D.A.1    Weiss, B.2    Cox, C.3
  • 23
    • 0026686821 scopus 로고
    • Cloning of an apparent splice variant of the rat N-methyl-D-aspartate recptor NMDAR1 with altered sensitivity to plyamines and activators of protein kinase C
    • Durand, G.M., Gregor, P., Zheng, X., Bennett, M.V.L., Uhl, G.R. and Zukin, S., Cloning of an apparent splice variant of the rat N-methyl-D-aspartate recptor NMDAR1 with altered sensitivity to plyamines and activators of protein kinase C, Proc. Natl. Acad. Sci. USA, 89 (1992) 9359-9363.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9359-9363
    • Durand, G.M.1    Gregor, P.2    Zheng, X.3    Bennett, M.V.L.4    Uhl, G.R.5    Zukin, S.6
  • 24
    • 0026619470 scopus 로고
    • Age-dependent effects of lead on [3H]MK-801 binding in NMDA receptor-gated ionophore: In vitro and in vivo studies
    • Guilarte, T.R. and Miceli, R.C., Age-dependent effects of lead on [3H]MK-801 binding in NMDA receptor-gated ionophore: in vitro and in vivo studies, Neurosci. Lett., 148 (1992) 27-30.
    • (1992) Neurosci. Lett. , vol.148 , pp. 27-30
    • Guilarte, T.R.1    Miceli, R.C.2
  • 26
    • 0028986970 scopus 로고
    • Biochemical evidence of an interaction of lead at the zinc allosteric sites of the NMDA receptor complex: Effects of neuronal development
    • Guilarte, T.R., Miceli, R.C. and Jett, D.A., Biochemical evidence of an interaction of lead at the zinc allosteric sites of the NMDA receptor complex: effects of neuronal development, Neurotoxicology, 16 (1995) 63-72.
    • (1995) Neurotoxicology , vol.16 , pp. 63-72
    • Guilarte, T.R.1    Miceli, R.C.2    Jett, D.A.3
  • 27
    • 0027197230 scopus 로고
    • Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor
    • Hollman, M., Boulter, J., Maron, C., Beasley, L., Sullivan, J., Pecht, G. and Heinemann, S., Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor, Neuron, 10 (1993) 943-954.
    • (1993) Neuron , vol.10 , pp. 943-954
    • Hollman, M.1    Boulter, J.2    Maron, C.3    Beasley, L.4    Sullivan, J.5    Pecht, G.6    Heinemann, S.7
  • 30
  • 31
    • 0028968422 scopus 로고
    • Developmental lead exposure alters N-methyl-D-aspartate and muscarinic cholinergic receptors in the rat hippocampus: An autoradiographic study
    • Jett, D.A. and Guilarte, T.R., Developmental lead exposure alters N-methyl-D-aspartate and muscarinic cholinergic receptors in the rat hippocampus: an autoradiographic study, Neurotoxicology, 16 (1995) 7-18.
    • (1995) Neurotoxicology , vol.16 , pp. 7-18
    • Jett, D.A.1    Guilarte, T.R.2
  • 33
    • 0024398705 scopus 로고
    • Systemically administered N-methyl-D-aspartate interferes with acquisition of a passive avoidance response in rats
    • Jones, K.W., Schaeffer, C.L. and DeNoble, V.J., Systemically administered N-methyl-D-aspartate interferes with acquisition of a passive avoidance response in rats, Pharmacol. Biochem. Behav., 34 (1989) 181-185.
    • (1989) Pharmacol. Biochem. Behav. , vol.34 , pp. 181-185
    • Jones, K.W.1    Schaeffer, C.L.2    DeNoble, V.J.3
  • 35
    • 0027208043 scopus 로고
    • Chronic exposure to environmental levels of lead impairs in vivo induction of long term potentiation in rat hippocampal dentate
    • Lasley, S.M., Polan-Curtain, J. and Armstrong, D.L., Chronic exposure to environmental levels of lead impairs in vivo induction of long term potentiation in rat hippocampal dentate, Brain Res., 614 (1993) 347-351.
    • (1993) Brain Res. , vol.614 , pp. 347-351
    • Lasley, S.M.1    Polan-Curtain, J.2    Armstrong, D.L.3
  • 36
    • 0028169661 scopus 로고
    • Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition
    • Laurie, D.J. and Seeburg, P.H., Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition, Eur. J. Pharmacol, 268 (1994) 335-345.
    • (1994) Eur. J. Pharmacol , vol.268 , pp. 335-345
    • Laurie, D.J.1    Seeburg, P.H.2
  • 37
    • 0022912470 scopus 로고
    • Preand postnatal lead exposure in monkeys: Effects on activity and learning set formation
    • Lilienthal, H., Winneke, G., Brockhaus, A. and Molik, B., Preand Postnatal lead exposure in monkeys: effects on activity and learning set formation, Neurotoxicol. Teratol., 8 (1986) 265-272.
    • (1986) Neurotoxicol. Teratol. , vol.8 , pp. 265-272
    • Lilienthal, H.1    Winneke, G.2    Brockhaus, A.3    Molik, B.4
  • 38
    • 84920302572 scopus 로고
    • Inhibition of NMDA receptors by lead is dependent on the receptor subunit composition
    • Lmelchenko, I.A., Nelson, C.S., Marino, J.L. and Allen, C.N., Inhibition of NMDA receptors by lead is dependent on the receptor subunit composition, Soc. Neurosci. Abstr., 21 (1995) 1984.
    • (1995) Soc. Neurosci. Abstr. , vol.21 , pp. 1984
    • Lmelchenko, I.A.1    Nelson, C.S.2    Marino, J.L.3    Allen, C.N.4
  • 40
    • 0027143968 scopus 로고
    • NMDA receptor blockers facilitate and impair learning via different mechanisms
    • Mondadori, C. and Weiskrantz, L., NMDA receptor blockers facilitate and impair learning via different mechanisms, Behav. Neural Biol., 60 (1993) 205-210.
    • (1993) Behav. Neural Biol. , vol.60 , pp. 205-210
    • Mondadori, C.1    Weiskrantz, L.2
  • 43
    • 0027339978 scopus 로고
    • Allosteric modulation of [3H]CGP 39653 binding by glycine in rat brain
    • Mugnaini, M., Gilberti, A., Ratti, E. and van Amsterdam, F.Th.M., Allosteric modulation of [3H]CGP 39653 binding by glycine in rat brain, J Neurochem., 61 (1993) 1492-1497.
    • (1993) J Neurochem. , vol.61 , pp. 1492-1497
    • Mugnaini, M.1    Gilberti, A.2    Ratti, E.3    Van Amsterdam, F.Th.M.4
  • 44
    • 0023038492 scopus 로고
    • Persistence of retention deficit in rats after neonatal lead exposure
    • Munoz, C., Garbe, K., Lilienthal, H. and Winneke, G., Persistence of retention deficit in rats after neonatal lead exposure, Neurotoxicology, 7 (1986) 569-580.
    • (1986) Neurotoxicology , vol.7 , pp. 569-580
    • Munoz, C.1    Garbe, K.2    Lilienthal, H.3    Winneke, G.4
  • 45
    • 0343169341 scopus 로고
    • Time-course of lead (Pb)-induced changes in D1, D2 and DAUC binding sites in dorsal striatum and nucleus accumbens during chronic postweaning exposure
    • abstr.
    • Pokora, M.J., Cory-Slechta, D.A. and Richfield, E.K., Time-course of lead (Pb)-induced changes in D1, D2 and DAUC binding sites in dorsal striatum and nucleus accumbens during chronic postweaning exposure, Soc. Neurosci. Abstr., 21 (1995) 94 (abstr.).
    • (1995) Soc. Neurosci. Abstr. , vol.21 , pp. 94
    • Pokora, M.J.1    Cory-Slechta, D.A.2    Richfield, E.K.3
  • 46
    • 84920295181 scopus 로고    scopus 로고
    • Preferential vulnerability of nucleus accumbens dopamine binding sites to low-level lead exposure: Time course of effects and interactions with chronic dopamine agonist treatments
    • in press
    • Pokora, M.J., Richfield, E.K. and Cory-Slechta, D.A., Preferential vulnerability of nucleus accumbens dopamine binding sites to low-level lead exposure: time course of effects and interactions with chronic dopamine agonist treatments, J. Neurochem., in press.
    • J. Neurochem.
    • Pokora, M.J.1    Richfield, E.K.2    Cory-Slechta, D.A.3
  • 47
    • 0028873061 scopus 로고
    • Regional variations in the pharmacology of NMDA receptor channel blockers: Implications for therapeutic potential
    • Porter, R.H.P. and Greenamyre, J.T., Regional variations in the pharmacology of NMDA receptor channel blockers: implications for therapeutic potential, J. Neurochem., 64 (1995) 614-623.
    • (1995) J. Neurochem. , vol.64 , pp. 614-623
    • Porter, R.H.P.1    Greenamyre, J.T.2
  • 48
    • 0028180245 scopus 로고
    • 2+ and polyamines independently of the arcaine-sensitive polyamine site
    • 2+ and polyamines independently of the arcaine-sensitive polyamine site, J. Neurochem., 62 (1994) 54-62.
    • (1994) J. Neurochem. , vol.62 , pp. 54-62
    • Reynolds, I.J.1
  • 49
    • 0021997767 scopus 로고
    • Chronic low-lead exposure from birth produces deficits in discrimination reversal in monkeys
    • Rice, D.C., Chronic low-lead exposure from birth produces deficits in discrimination reversal in monkeys. Toxicol. Appl. Pharmacol., 75 (1985) 201-210.
    • (1985) Toxicol. Appl. Pharmacol. , vol.75 , pp. 201-210
    • Rice, D.C.1
  • 51
    • 0028987683 scopus 로고
    • Glutamate/dopamine D1/D2 balance in the basal ganglia and its relevance to Parkinson's disease
    • Starr, M.S., Glutamate/dopamine D1/D2 balance in the basal ganglia and its relevance to Parkinson's disease, Synapse, 19 (1995) 264-293.
    • (1995) Synapse , vol.19 , pp. 264-293
    • Starr, M.S.1
  • 52
    • 0026766877 scopus 로고
    • Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing
    • Sugihara, H., Moriyoshi, K., Ishii, T., Masu, M. and Nakanishi, S., Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing, Biochem. Biophys. Res. Commun., 185 (1992) 826-832.
    • (1992) Biochem. Biophys. Res. Commun. , vol.185 , pp. 826-832
    • Sugihara, H.1    Moriyoshi, K.2    Ishii, T.3    Masu, M.4    Nakanishi, S.5
  • 53
    • 0026454799 scopus 로고
    • Developmental change of the inhibition by lead of NMDA-activated currents in cultured hippocampal neurons
    • Ujihara, H. and Albuquerque, E.X., Developmental change of the inhibition by lead of NMDA-activated currents in cultured hippocampal neurons, J. Pharmacol. Exp. Ther., 263 (1993) 868-875.
    • (1993) J. Pharmacol. Exp. Ther. , vol.263 , pp. 868-875
    • Ujihara, H.1    Albuquerque, E.X.2
  • 55
    • 0028603401 scopus 로고
    • Time course of postnatal lead-induced changes in dopamine receptors and their relationship to changes in dopamine sensitivity
    • Widzowski, D.V., Finkelstein, J.N., Pokora, M.J., Johnson, S.C. and Cory-Slechta, D.A., Time course of postnatal lead-induced changes in dopamine receptors and their relationship to changes in dopamine sensitivity, Neurotoxicology, 15 (1994) 294-308.
    • (1994) Neurotoxicology , vol.15 , pp. 294-308
    • Widzowski, D.V.1    Finkelstein, J.N.2    Pokora, M.J.3    Johnson, S.C.4    Cory-Slechta, D.A.5
  • 56
    • 84920301821 scopus 로고
    • Alterations in N-methyl-D-aspartate (NMDA) receptor subunit mRNA after lead treatment in neonatal rats
    • Wilson, M.A., Bressler, J., Johnston, M.V. and Goldstein, G.W., Alterations in N-methyl-D-aspartate (NMDA) receptor subunit mRNA after lead treatment in neonatal rats, Soc. Neurosci. Abstr., 21 (1995) 1984.
    • (1995) Soc. Neurosci. Abstr. , vol.21 , pp. 1984
    • Wilson, M.A.1    Bressler, J.2    Johnston, M.V.3    Goldstein, G.W.4
  • 57
    • 0017753231 scopus 로고
    • Neurobehavioral and systemic effects of longterm blood-lead elevation in rats. I. Discrimination learning and open field behavior
    • Winneke, G., Brockhaus, A. and Batissen, R., Neurobehavioral and systemic effects of longterm blood-lead elevation in rats. I. Discrimination learning and open field behavior, Arch. Toxicol., 37 (1977) 247-263.
    • (1977) Arch. Toxicol. , vol.37 , pp. 247-263
    • Winneke, G.1    Brockhaus, A.2    Batissen, R.3
  • 59
    • 37049187166 scopus 로고
    • Drug-discrimination learning in lead-exposed rats
    • Zenick, H. and Goldsmith, M., Drug-discrimination learning in lead-exposed rats, Science, 212 (1981) 569-571.
    • (1981) Science , vol.212 , pp. 569-571
    • Zenick, H.1    Goldsmith, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.