Endotoxin removal by direct hemoperfusion with an adsorbent column using polymyxin B-immobilized fiber ameliorates systemic circulatory disturbance in patients with septic shock

American Journal of Kidney Diseases

Volumn 39, Issue 5, 2002, Pages 937-947

  Uriu, Kohei ^a   Osajima, Akihiko ^a   Hiroshige, Kinya ^a   Watanabe, Hiroyuki ^a   Aibara, Keiji ^a   Inada, Yoshifumi ^a   Segawa, Kayoko ^a   Anai, Hiroshi ^a   Takagi, Ichiro ^a   Ito, Aki ^a   Kamochi, Masayuki ^a   Kaizu, Kazo ^b  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b Social Insurance Chikuho Hospital   (Japan)

Author keywords

Direct hemoperfusion (DHP); Endotoxin; Polymyxin B; Septic shock

Indexed keywords

ADSORBENT; ENDOTOXIN; POLYMYXIN B;

ADULT; AGED; ARTICLE; BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DEVICE; ENDOTOXEMIA; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HEART OUTPUT; HEART PERFORMANCE; HEMODYNAMIC MONITORING; HEMOPERFUSION; HUMAN; MEAN ARTERIAL PRESSURE; OUTCOMES RESEARCH; SEPTIC SHOCK; SYSTEMIC CIRCULATION; SYSTEMIC VASCULAR RESISTANCE; TECHNIQUE;

EID: 0036237335     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1053/ajkd.2002.32767     Document Type: Article

References (46)

1. Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy
2. Treating patients with severe sepsis
3. Gram-positive organisms and sepsis
4. Hemodynamic determinants of mortality in human septic shock
5. Early hemodynamic course of septic shock
6. Profound but reversible myocardial depression in patients with septic shock
7. Selected treatment strategies for septic shock based on proposed mechanisms of pathogenesis
8. Extracorporeal adsorbent-based strategies in sepsis
9. Cardiopulmonary consequences of pyrogen-induced hyperpyrexia in man
10. The cardiovascular response of normal humans to the administration of endotoxin
11. Anti-inflammatory therapies to treat sepsis and septic shock: A reassessment
12. An international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor α in patients with sepsis
13. Treatment of septic shock with the tumor necrosis factor receptor: Fc fusion protein
14. Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: A phase III, randomized, double-blind, placebo-controlled multicenter trial
15. New approach to endotoxic and septic shock by means of polymyxin B immobilized fiber
16. Neutralization of the hemodynamic effects of endotoxin by polymyxin B
17. Polymyxin B sulfate modification of bacterial endotoxin: Effects on the development of endotoxin-shock in dogs
18. Effects of polymyxin B on experimental shock from meningococcal and Escherichia coli endotoxins
19. Inactivation of endotoxin by polymyxin B
20. Endotoxin binding by charged and uncharged resins
21. Removal of endotoxin by a polymyxin B affinity column
22. Inactivation and immobilization of endotoxin: A novel endotoxin binding substances, polymyxin sepharose
23. Extracorporeal endotoxin removal by polymyxin B immobilized fiber cartridge: Designing and antiendotoxin efficacy in the clinical application
24. Treatment of sepsis by extracorporeal elimination of endotoxin using polymyxin B-immobilized fiber
25. Diagnostic methods for bacterial, rickettsial, mycoplasmal, and fungal infections
26. A new chromogenic endotoxin-specific assay using recombined limulus coagulation enzymes and its clinical applications
27. A lipid A analog, E5531, blocks the endotoxin response in human volunteers with experimental endotoxemia
28. Endotoxin-induced left ventricular depression is blocked by nitrogen mustard or dimethylthiourea in rabbits
29. Biphasic changes in left ventricular function during hyperdynamic endotoxemia
30. Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human septic shock
31. Endotoxin and tumor necrosis factor alpha exert a similar proinflammatory effect in neonatal rat cardiomyocytes, but have different cardiodepressant profiles
32. Optimum left heart filling pressure during fluid resuscitation of patients with hypovolemic and septic shock
33. Depressed left ventricular performance. Response to volume infusion in patients with sepsis and septic shock
34. Platelet and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension
35. Polymyxin B binds to anandamide and inhibits its cytotoxic effect
36. Aminoethyl-isothiourea, a nitric oxide synthase inhibitor and oxygen radical scavenger, improves survival and counteracts hemodynamic deterioration in a porcine model of streptococcal shock
37. Nitric oxide synthase inhibition partially prevents decreased LV contractility during endotoxemia
38. Endotoxemia and acute-phase proteins in major abdominal surgery
39. Upregulation of Tolllike receptor 2 gene expression in macrophage response to peptidoglycan and high concentration of lipopolysaccharide is involved in NF-κB activation
40. Prolonged expression of lipopolysaccharide (LPS)-induced inflammatory genes in whole blood requires continual exposure to LPS
41. Plasma cytokine and endotoxin levels correlate with survival in patients with the septic syndrome
42. Endotoxemia: An early predictor of septicaemia in febrile patients
43. Endotoxemia in human septic shock
44. Gram-positive sepsis
45. Comparison of hemodynamic changes resulting from toxic shock syndrome toxin-1-producing Staphylococcus aureus sepsis and endotoxin-producing gram-negative rod sepsis in patients with severe burns
46. Persistent preload defect in severe sepsis despite fluid loading. A longitudinal echocardiographic study in patients with septic shock