Molecular biology and immunoregulation of human neurotropic JC virus in CNS

Journal of Cellular Physiology

Volumn 191, Issue 3, 2002, Pages 249-256

  Sweet, Thersa M ^a   Del Valle, Luis ^a   Khalili, Kamel ^a  

^a TEMPLE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SMAD PROTEIN; TRANSCRIPTION FACTOR;

ANTIBODY TITER; CYTOLYSIS; DEMYELINATING DISEASE; GENE ACTIVATION; GENE EXPRESSION; GLIA CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE DEFICIENCY; IMMUNE SYSTEM; IMMUNOREGULATION; JC VIRUS; LATENT VIRUS INFECTION; MOLECULAR BIOLOGY; NERVOUS SYSTEM; NONHUMAN; PATHOGENESIS; POLYOMA VIRUS; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; PROMOTER REGION; REVIEW; SIGNAL TRANSDUCTION; VIRUS GENOME; VIRUS INFECTION; VIRUS REACTIVATION; VIRUS REPLICATION;

CENTRAL NERVOUS SYSTEM; GENE EXPRESSION REGULATION; HIV-1; HUMANS; IMMUNE SYSTEM; IMMUNOSUPPRESSION; JC VIRUS; LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL; MOLECULAR BIOLOGY; VIRUS ACTIVATION; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1; JC VIRUS; POLYOMAVIRUS;

EID: 0036233810     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.10096     Document Type: Review

References (99)

1. Expression of major histocompatibility complex antigens in the brains of patients with progressive multifocal leukoencephalopthy
2. Progressive multifocal leukoencephalopathy: A hitherto unrecognized complication of chronic lymphatic leukemia and Hodgkin's disease
3. The inducible transcription activator NFκB: Regulation by distinct subunits
4. Progressive multifocal leukoencephalopathy associated with human immunodeficiency virus infection: Review of the literature with a report of sixteen cases
5. Tat transactivates the human immunodeficiency virus through a nascent RNA target
6. TAR-independent activation of the HIV-1 LTR: Evidence that Tat requires specific regions of the promoter
7. Progressive multifocal leukoencepalopathy
8. Persistence of DNA sequences of BK virus and JC virus in normal human tissues and in diseased tissues
9. Regulation of the human neurotropic virus promoter by JCV T-antigen and HIV-1 tat protein
10. Evidence that a sequence similar to TAR is important for induction of the JC virus late promoter by human immunodeficiency virus type 1 Tat
11. L, in cells derived from CNS
12. A prospective study of human polyomavirus infection in pregnancy
13. Human polyomavirus in pregnancy: A model for the study of defense mechanisms to virus reactivation
14. The HIV-1 Tat protein: An RNA sequence-specific processivity factor?
15. Coordinate effects of human immunodeficiency virus type 1 protein Tat and cellular protein Pura on DNA replication initiated at the JC virus origin
16. Progressive multifocal leukoencephalopathy: Analysis of JC virus DNA from brain and kidney tissue
17. JCV-specific cellular immune response correlates with a favorable clinical outcome in HIV-infected individuals with progressive multifocal leukoencephalopathy
18. Tat protein of HIV-1 stimulates growth of Kaposi's sarcoma lesion of AIDS patients
19. Regulation of the host range of human papovavirus JCV
20. JC virus and simian virus 40 enhancers and transforming proteins: Role in determining tissue specificity and pathogenicity in transgenic mice
21. The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongation
22. Amplification and sequencing of the control regions of BK and JC virus from human urine by polymerase chain reaction
23. Activation of HIV transcription by Tat
24. Cellular uptake of the Tat protein from human immunodeficiency virus
25. The molecular biology of JC virus causative agent of progressive multifocal leukencephalopathy
26. Human polyomavirus JC virus genome
27. Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system: An evaluation of cytokines in cerebrospinal fluid
28. Prevalence in England of antibody to human polyomavirus (BK)
29. Prospective study of the human polyomaviruses BK and JC and cytomegalovirus in renal transplant recipients
30. Cytokines and arachidonic metabolites produced during human deficiency virus (HIV)-infected macrophage-astroglia interaction: Implication for the neuropathogenesis of HIV disease
31. NF-κB and Rel proteins: Evolutionarily conserved mediators of immune responses
32. Elevated alpha-tumor necrosis factor levels in spinal fluid from HIV-1 infected patients with central nervous system involvement
33. Progressive multifocal leukoencephalopathy: Simultaneous detection of JCV DNA and anti-JCV antibodies in the cerebrospinal fluid
34. TGFβ signaling from cell membrane to nucleus through SMAD proteins
35. Acquired immunodeficiency syndrome with progressive multifocal leukoencephalopathy and monoclonal B-cell proliferation
36. Human polyomavirus infections with JC virus and BK virus in renal transplants patients
37. Involvement of JC virus-infected mononuclear cells from the bone marrow and spleen in the pathogenesis of progressive multifocal leukoencephalopathy
38. Tumor necrosis factor stimulates transcription of HIV-1 in human T lymphocytes, independently and synergistically with mitogens
39. Kinetics of HIV-1 long terminal repeat transactivation
40. How NF-κB is activated: The role of the IκB kinase (IKK) complex
41. Tackling Tat
42. JC virus enhancer-promoter active in human brain cells
43. Spontaneous progressive multifocal leukoencephalopathy: Immunologic aspects
44. JC virus-specific cytotoxic T lymphocytes in individuals with progressive multifocal leukoencephalopathy
45. Association of prolonged survival in HLA-A2(+) progressive multifocal leukoencephalopathy patients with a CTL response specific for a commonly recognized JC virus epitope
46. Activation of the JC virus Tat-responsive transcriptional control element by association of the Tat protein of human immunodeficiency virus 1 with cellular protein, Purα
47. Regulation of JCVL promoter function. Transactivation of JCVL promoter by JCV and SV40 early proteins
48. HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation
49. Synergy between HIV-1 Tat and adenovirus E1A is principally due to stabilization of transcriptional elongation
50. Is JC virus latent in brain?
51. DNA rearrangements in organ-specific variants of polyomavirus JC strain GS
52. Induction of transforming growth factor β (TGFβ) by HIV-1 Tat: A noncytopathic pathway of immunodeficiency in HIV infection
53. Glial cells of the human developing brain and B cells of the immune system share a common DNA binding factor for recognition of the regulatory sequences of the human polyomavirus, JCV
54. Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain
55. Human papovaviruses: JC virus, progressive multifocal leukoencephalopathy, and model systems for tumors of the central nervous system
56. A human papova virus (BK): Biological properties and seroepidemiology
57. Progressive multifocal leukoencephalopathy: Remission with cytarabine
58. TGFβ signal transduction
59. Multiple central nervous system infections in progressive multifocal leukoencephalopathy
60. Transcription of the JC virus archetype late genome: Importance of the κB and the 23-base-pair motifs in late promoter activity in glial cells
61. Cytokines and retroviruses
62. HIV-1, macrophages, glial cells, and cytokines in AIDS nervous system disease
63. JC virus detection in brain tissue from elderly patients by in situ hybridization
64. Expression of cytokines in brain lesions in subacute sclerosing panencephalitis
65. Tumor necrosis factor an interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor κB
66. Prevalence of antibodies in human sera against JC virus, an isolate from a case of progressive multifocal leukoencephalopathy
67. New human papovaviruses
68. Activators and target genes of Rel/NF-κB transcription factors
69. Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis
70. Identification and characterization of a novel GGA/C-binding protein, GBP-i, that is rapidly inducible by cytokines
71. Transcriptional regulation: Lessons from the human neurotropic polyomavirus, JCV
72. The transcriptional enhancer element, κB, regulates promoter activity of the human neurotropic virus, JCV, in cells derived from the CNS
73. Progressive multifocal leukoencephalopathy
74. A nuclear factor I binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor beta
75. A 23 bp sequence element from human neurotropic JC virus is responsive to NF-κB subunits
76. The early region of human papovavirus JC induces dysmyelination in transgenic mice
77. Cell type-specific expression of JC virus early promoter is determined by positive and negative regulation
78. Transactivation of the JC virus late promoter by the tat protein of type 1 human immunodeficiency virus in glial cells
79. Activation of expression of genes coding for extracellular matrix proteins in Tat-producing glioblastoma cells
80. Detection of JC virus DNA by polymerase chain reaction in patients with progressive multifocal leukoencephalopathy
81. Persistent human immunodeficiency virus type 1 infection in human fetal glial cells reactivated by T-cell factor(s) or by cytokines tumor necrosis factor alpha and interleukin-1 beta
82. Detection of JC virus DNA in peripheral lymphocytes from patients with and without progressive multifocal leukoencephalopathy
83. Cytokine expression in the brain during the acquired immunodeficiency syndrome
84. Cytokine expression of macrophages in HIV-1 associated vacuolar myelopathy
85. Induction of peripheral neuroblastomas in Syrian hamsters after injection as neonates with JC virus human polyoma virus
86. Transforming growth factor type β induces monocyte chemotaxis and growth factor production
87. Macrophage- and astrocyte-derived transforming growth factor β as a mediator of central nervous system dysfunction in acquired immunodeficiency syndrome
88. Progressive multifocal leukoencephalopathy
89. Cellular and humoral immune response in progressive multifocal leukoencephalopathy
90. JC virus DNA is present in many human brain samples from patients without progressive multifocal leukoencephalopathy
91. Progressive multifocal leukoencephalopathy (PML): In vitro cell-mediated immune responses to mitogens and JC virus
92. In vitro replication of duplex circular DNA containing the simian virus 40 DNA origin site
93. Interaction of HIV-1 Tat with Pura in nuclei of human glial cells: Characterization of RNA-mediated protein-protein binding
94. Isolation of a possible archetypical JC virus DNA sequence from nonimmunocompromised individuals
95. Receptor-associated Mad homologues synergize as effectors of the TGFβ response
96. Polyoma-like virions in a human demyelinating disease
97. Association of papova-virions with a human demyelinating disease (progressive multifocal leukoencephalopathy)
98. Particles resembling papovavirues in human cerebral demyelinating disease