Characterization of cytochrome b from Toxoplasma gondii and Q(o) domain mutations as a mechanism of atovaquone-resistance

Molecular and Biochemical Parasitology

Volumn 108, Issue 1, 2000, Pages 1-12

  McFadden, Diane C ^a   Tomavo, Stanislas ^b   Berry, Edward A ^c   Boothroyd, John C ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITÉ DES SCIENCES ET TECHNOLOGIES DE LILLE   (France)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Drug resistance; Electron transport; Inhibition; Mitochondria; Plasmodium; Stop codon

Indexed keywords

ATOVAQUONE; CYTOCHROME B; NAPHTHOQUINONE;

ARTICLE; BINDING AFFINITY; ELECTRON TRANSPORT; GENE EXPRESSION; GENE SEQUENCE; MITOCHONDRION; MOLECULAR CLONING; MUTATION; NUCLEOTIDE SEQUENCE; PLASMODIUM; PRIORITY JOURNAL; PROTEIN ANALYSIS; STOP CODON; TOXOPLASMA GONDII; TOXOPLASMOSIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIPROTOZOAL AGENTS; ATOVAQUONE; BINDING SITES; BLOTTING, NORTHERN; CYTOCHROME B GROUP; DRUG RESISTANCE; DRUG RESISTANCE, MULTIPLE; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NAPHTHOQUINONES; PROTEIN CONFORMATION; PROTOZOAN PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TOXOPLASMA; UBIQUINONE;

PROTOZOA; TOXOPLASMA GONDII;

EID: 0034732665     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(00)00184-5     Document Type: Article

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