Effects of STA2, a thromboxane A2 mimetic, in inducing airflow obstruction and airway microvascular leakage in guinea pigs

Pharmacology

Volumn 65, Issue 2, 2002, Pages 62-68

  Inoue, Yoshinari ^a   Tokuyama, Kenichi ^a   Nishimura, Hideko ^a   Arakawa, Hirokazu ^a   Kato, Masahiko ^a   Mochizuki, Hiroyuki ^a   Morikawa, Akihiro ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

Asthma; Edema; Eicosanoid; Endothelial gap; Plasma exudation; Plasma leakage; Prostanoid; TXA2synthase inhibitor; Vascular leakage

Indexed keywords

15 CYCLOPENTYL 14 OXO 13 AZA 16,17,18,19,20 PENTANORPINANE THROMBOXANE A2; 15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 9,11 EPITHIO 11,12 METHANOTHROMBOXANE A2; DOMITROBAN; EVANS BLUE; THROMBOXANE A2 RECEPTOR; THROMBOXANE A2 RECEPTOR BLOCKING AGENT;

AIRWAY OBSTRUCTION; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG RECEPTOR BINDING; EXTRAVASATION; GUINEA PIG; LUNG RESISTANCE; MALE; MICROVASCULATURE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; VASCULAR DISEASE;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; AIRWAY OBSTRUCTION; AIRWAY RESISTANCE; ANIMALS; BICYCLO COMPOUNDS; BLOOD PRESSURE; CAPILLARY PERMEABILITY; DOSE-RESPONSE RELATIONSHIP, DRUG; EVANS BLUE; EXTRAVASATION OF DIAGNOSTIC AND THERAPEUTIC MATERIALS; FATTY ACIDS, MONOUNSATURATED; GUINEA PIGS; LUNG; MALE; PLATELET AGGREGATION INHIBITORS; THROMBOXANE A2; TIME FACTORS; VASOCONSTRICTOR AGENTS;

EID: 0036221742     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000056188     Document Type: Article

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