U46619 (a thromboxane A2 mimetic) induces airflow obstruction and airway plasma extravasation in the guinea pig: The role of histamine, cyclooxygenase metabolites, leukotrienes and PAF

Journal of Pharmacology and Experimental Therapeutics

Volumn 278, Issue 1, 1996, Pages 268-276

  Kawikova, Ivana ^a   Arakawa, Hirokazu ^b   Skoogh, Bengt Eric ^b   Löfdahl, Claes Göran ^b   Lötvall, Jan ^b  

^a Lung Pharmacology Group   (Sweden)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 METHOXY 4 [(PHENYLSULFONYLAMINO)CARBONYL]BENZYL] 1H INDAZOLE 6 CARBAMIC ACID CYCLOPENTYL ESTER; 1 [3 [3 (4 FLUOROPHENYL)PHENOXY] 1 METHYLALLYL] 1 HYDROXYUREA; 15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 6 [2 (2 CHLOROPHENYL) 4 (2 HYDROXYPHENYL) 1,3 DIOXAN 5 YL] 4 HEXENOIC ACID; APAFANT; HISTAMINE; INDOMETACIN; LEUKOTRIENE; LIPOXYGENASE INHIBITOR; MEPYRAMINE; THROMBOCYTE ACTIVATING FACTOR; THROMBOXANE A2 RECEPTOR STIMULATING AGENT; DRUG DERIVATIVE; PROSTAGLANDIN ENDOPEROXIDE; PROSTAGLANDIN SYNTHASE; THROMBOXANE A2; VASOCONSTRICTOR AGENT;

AIRWAY OBSTRUCTION; AIRWAY PRESSURE; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BRONCHOSPASM; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG POTENCY; DRUG POTENTIATION; EXTRAVASATION; GUINEA PIG; INTRATRACHEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CONTRAST MEDIUM EXTRAVASATION; DRUG EFFECT; LUNG VENTILATION; METABOLISM; TRACHEA;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRAVASATION OF DIAGNOSTIC AND THERAPEUTIC MATERIALS; GUINEA PIGS; HISTAMINE; LEUKOTRIENES; MALE; PROSTAGLANDIN ENDOPEROXIDES, SYNTHETIC; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PULMONARY VENTILATION; THROMBOXANE A2; TRACHEA; VASOCONSTRICTOR AGENTS;

EID: 0030302495     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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