Mechanical ventilation alters the immune response in children without lung pathology

Intensive Care Medicine

Volumn 28, Issue 4, 2002, Pages 486-492

  Plötz, Frans B ^a,b   Vreugdenhil, Harriet A ^a   Slutsky, Arthur S ^c   Zijlstra, Jitske ^a   Heijnen, Cobi J ^a   Van Vught, Hans ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ST ANTONIUS HOSPITAL   (Netherlands)

^c ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

Cardiac catheterization; Interferon ; Interleukins; Mechanical ventilation; Natural killer cells; Tumor necrosis factor ; Volatile anesthetics

Indexed keywords

ANESTHETIC AGENT; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 6; SERVOFLURANE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; ARTIFICIAL VENTILATION; ASPIRATION; BLOOD SAMPLING; CELL ACTIVITY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; HEART CATHETERIZATION; HUMAN; IMMUNE RESPONSE; INFANT; LEUKOCYTE; NATURAL KILLER CELL; TH1 CELL; TH2 CELL; TIDAL VOLUME; TRACHEA;

ANESTHETICS; CHILD; CHILD, PRESCHOOL; CYTOKINES; HEART CATHETERIZATION; HUMANS; IMMUNITY, CELLULAR; INFANT; INTERFERON TYPE II; INTERLEUKINS; KILLER CELLS, NATURAL; LYMPHOCYTES; PROSPECTIVE STUDIES; RESPIRATION, ARTIFICIAL; STATISTICS, NONPARAMETRIC;

EID: 0036220760     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00134-002-1216-7     Document Type: Article

References (32)

1. Cytokines and the acute respiratory distress syndrome (ARDS): A question of balance
2. Dominance of T-helper 2-type cytokines after severe injury
3. Human Th1 and Th2 subsets: Doubt no more
4. Anti-IL-4 treatment at immunization modulates cytokine expression, reduces illness, and increases cytotoxic T lymphocyte activity in mice challenged with respiratory syncytial virus
5. The acute respiratory distress syndrome
6. Ventilator-induced lung inflammation: Is it always harmful?
7. Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model
8. Role of high-frequency ventilation in surfactant-depleted lung injury as measured by granulocytes
9. Inflammatory chemical mediators during conventional ventilation and during high frequency oscillatory ventilation
10. Ventilator pattern influences neutrophil influx and activation in atelectasis-prone rabbit lung
11. Intraalveolar expression of tumor necrosis factor-alpha gene during conventional and high-frequency ventilation
12. Multiple system organ failure: Is mechanical ventilation a contributing factor?
13. Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: A randomized clinical trial
14. Mechanical ventilation as a mediator of multisystem organ failure in acute respiratory distress syndrome
15. Compartmentalized lung cytokine release in response to intravascular and alveolar endotoxin challenge
16. Loss of compartmentalization of alveolar tumor necrosis factor after lung injury
17. Ventilator-induced lung injury
18. Measurement of interleukin 10 in bronchoalveolar lavage from preterm ventilated infants
19. A convenient whole blood culture system for studying the regulation of tumor necrosis factor release by bacterial lipopolysaccharide
20. Monocyte IL-10 production during respiratory syncytial virus bronchiolitis is associated with recurrent wheezing in a one year follow-up study
21. Altered immune function in human newborns after prenatal administration of betamethasone: Enhanced natural killer cell activity and decreased T cell proliferation in cor blood
22. Immunomodulation by anaesthetic, sedative and analgesic agents: Does it matter?
23. Volatile anesthetics augment expression of proinflammatory cytokines in rat alveolar macrophages during mechanical ventilation
24. Expression of genes for proinflammatory cytokines in alveolar macrophages during propofol and isoflurane anesthesia
25. Intratracheal anti-tumor necrosis factor-alpha antibody attenuates ventilator induced lung injury in rabbits
26. Mechanical ventilation of various human lung cells in vitro: Identification of the macrophage as the main producer of inflammatory mediators
27. Changes in cytokine expression secondary to injurious mechanical ventilation strategies in an ex vivo lung model
28. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome
29. Inflammatory pulmonary edema and positive end-expiratory pressure: Correlations between imaging and physiologic studies
30. Effects of mechanical ventilation on release of cytokines into systemic circulation in patients with normal pulmonary function
31. Th1/Th2 subsets: Distinct differences in homing and chemokine receptor expression?