Mechanical ventilation of various human lung cells in vitro: Identification of the macrophages as the main producer of inflammatory mediators

Chest

Volumn 116, Issue SUPPL., 1999, Pages 95S-97S

  Dunn, Irène ^a   Pugin, Jérôme ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR;

ARTIFICIAL VENTILATION; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG ALVEOLUS CELL; LUNG ALVEOLUS MACROPHAGE; LUNG INJURY; MECHANICAL STRESS; MEDIATOR RELEASE; PATHOPHYSIOLOGY; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL;

EID: 0032788908     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.116.suppl_1.95S     Document Type: Conference Paper

References (10)

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3. Pugin J, Jolliet P. Ventilator-induced lung injury: an inflammatory disease? Clin Pulm Med 1998; 5:290-299
4. Pugin J, Dunn I, Jolliet P, et al. Activation of human macrophages by mechanical ventilation in vitro. Am J Physiol 1998; 275:1040-1045
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8. Slutsky AS, Tremblay LN. Multiple system organ failure: is mechanical ventilation a contributing factor? Am J Respir Crit Care Med 1998; 157:1721-1725
9. Pugin J, Verghese G, Widmer M-C, et al. The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome. Crit Care Med 1999; 27:304-312
10. Pittet JF, Mackersie RC, Martin TR, et al. Biological markers of acute lung injury: prognostic and pathogenetic significance. Am J Respir Crit Care Med 1997; 155:1187-1205