Covalent binding of nitrogen mustards to the cysteine-34 residue in human serum albumin

Archives of Toxicology

Volumn 76, Issue 2, 2002, Pages 83-88

  Noort, Daan ^a   Hulst, Albert G ^a   Jansen, Rob ^b  

^a TNO   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Adducts; Albumin; Biomonitoring; Chemotherapy; Nitrogen mustards; Tandem mass spectrometry

Indexed keywords

CHLORAMBUCIL; CHLORMETHINE; CHLORMETHINE DERIVATIVE; CYCLOPHOSPHAMIDE; CYSTEINE; DICHLORODIETHYLAMINE; HUMAN SERUM ALBUMIN; MELPHALAN; PHENYLALANINE; PROLINE; PRONASE; TRIPEPTIDE;

AMINO ACID ANALYSIS; ARTICLE; CONTROLLED STUDY; COVALENT BOND; DRUG PROTEIN BINDING; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

BINDING SITES; CHLORAMBUCIL; CYCLOPHOSPHAMIDE; CYSTEINE; DRUG MONITORING; HUMANS; MECHLORETHAMINE; MELPHALAN; NITROGEN MUSTARD COMPOUNDS; PROTEIN BINDING; SERUM ALBUMIN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

BRASSICACEAE;

EID: 0036210212     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-001-0318-2     Document Type: Article

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