Blood-borne signals that induce anterior chamber-associated immune deviation after intracameral injection of antigen

Investigative Ophthalmology and Visual Science

Volumn 38, Issue 11, 1997, Pages 2245-2254

  Streilein, J Wayne ^a   Okamoto, Shigeki ^a   Hara, Yoshiyuki ^a   Kosiewicz, Michele ^a   Ksander, Bruce ^a  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

ACAID inducing signals; Anterior chamber associated immune deviation; Cell associated antigens; Delayed hypersensitivity; Soluble antigens

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR EYE CHAMBER; ARTICLE; CONTROLLED STUDY; IMMUNITY; IMMUNOGENICITY; IMMUNOMODULATION; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SENSITIZATION;

ANIMALS; ANTERIOR CHAMBER; ANTIGENS; B-LYMPHOCYTES; BLOOD; HYPERSENSITIVITY, DELAYED; INJECTIONS; MICE; MICE, INBRED BALB C; MICE, SCID; MINOR HISTOCOMPATIBILITY ANTIGENS; MYCOBACTERIUM; PERITONEAL CAVITY; SERUM ALBUMIN, BOVINE; T-LYMPHOCYTES; TUMOR CELLS, CULTURED;

EID: 0030864633     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Kaplan HJ, Streilein JW. Immune response to immunization via the anterior chamber of the eye. I. F1 lymphocyte-induced immune deviation. J Immunol. 1977; 118:809-814.
2. Streilein JW, Niederkorn JY, Shadduck JA. Systemic immune unresponsiveness induced in adult mice by anterior chamber presentation of minor histocompatibility antigens. J Exp Med. 1980;152:1121-1125.
3. Eichorn M, Horneber M, Streilein JW, Lutjen-Drecoll E. Anterior chamber-associated immune deviation elicited via primate eyes. Invest Ophthalmol Vis Sci. 1993;34:2926-2930.
4. Streilein JW. Immune regulation and the eye: A dangerous compromise. FASEB J. 1987;1:199-208.
5. Niederkorn JY. Immune privilege and immune regulation in the eye. Adv Immunol. 1990;48:191-226.
6. Kosiewicz MM, Okamoto S, Miki S, Ksander BR, Shimizu T, Streilein JW. Imposing deviant immunity on the presensitized state. J Immunol. 1994;153:2962-2973.
7. Wilbanks GA, Streilein JW. The differing patterns of antigen release and local retention following anterior chamber and intravenous inoculation of soluble antigen. Regional Immunol. 1991;2:390-398.
8. Wilbanks GA, Streilein JW. Studies on the induction of anterior chamber-associated immune deviation (ACAID). I. Evidence that an antigen-specific, ACAID-inducing, cell-associated signal exists in the peripheral blood. J Immunol. 1991;146:2610-2617.
9. Wilbanks GA, Mammolenti MM, Streilein JW. Studies on the induction of anterior chamber-associated immune deviation (ACAID). II. Eye-derived cells participate in generating bloodborne signals that induce ACAID. J Immunol. 1991;146:3018-3024.
10. Ferguson T, Hayashi J, Kaplan H. The immune response and the eye. III. Anterior chamber-associated immune deviation can be adoptively transferred by serum. J Immunol. 1989;143:821-826.
11. Ferguson TA, Herndon JM. The immune response and the eye: The ACAID-inducing signal is dependent on the nature of the antigen. Invest Ophthalmol Vis Sci. 1994;35:3085-3093.
12. Ksander BR, Bando Y, Acevedo J, Streilein JW. The infiltration and accumulation of precursor cytotoxic T cells increases with time in progressively growing ocular tumors. Cancer Res. 1991;51:3153-3158.
13. Wilbanks GA, Mammolenti MM, Streilein JW. Studies on the induction of anterior chamber-associated immune deviation (ACAID). III. Induction of ACAID depends upon intraocular transforming growth factor-β. Eur J Immunol. 1992;2:165-173.
14. Wilbanks GA, Streilein JW. Distinctive humoral responses following anterior chamber and intravenous administration of soluble antigen. Evidence for active suppression of IgG2a-secreting B cells. Immunology. 1990;71:566-572.
15. Griffith TS, Herndon JM, Lima J, Kahn M, Ferguson TA. The immune response and the eye. TCR α-chain related molecules regulate the systemic immunity to antigen presented in the eye. Internat Immunol. 1995; 7:1617-1625.
16. Hara Y, Caspi RR, Wiggert B, Chan C-C, Wilbanks GA, Streilein JW. Suppression of experimental autoimmune uveitis in mice by induction of anterior chamber-associated immune deviation with interphotoreceptor retinoid binding protein. J Immunol. 1992; 148:1685-1692.
17. Hadjikouti CA, Wang Y, O'Rourke J, Cone RE. Intracameral injection of antigen potentiates the production of antigen-specific T cell proteins in serum after the induction of delayed-type hypersensitivity. Invest Ophthalmol Vis Sci. 1995;36:1470-1476.
18. Cone RE, Wang Y, O'Rourke J, Kosiewicz M, Okamoto S, Streilein JW. On the role of extracellular, antigen-specific T cell proteins in immune deviation elicited by intracameral soluble protein antigens. In: Nussenblatt RB, Whitsup SM, Caspi RR, Gery I, eds. Advances in Ocular Immunology. Amsterdam: Elsevier Science BV; 1994:169-174.
19. Griffith TS, Brunner T, Fletcher SM, Green DR, Ferguson TA. Fas ligand-induced apoptosis as a mechanism of immune privilege. Science. 1995;270:1189-1192.
20. Rohen JW, van der Zypen E. The phagocytic activity of the trabecular meshwork endothelium. An electron microscopic study of the vervet. Graefes Arch Ophthalmol. 1968;175:143-160.
21. Wilbanks G, Streilein JW. Macrophages capable of inducing anterior chamber-associated immune deviation demonstrate spleen-seeking properties. Regional Immunol. 1992;4:130-137.
22. Hara Y, Okamoto S, Rouse B, Streilein JW. Evidence that peritoneal exudate cells cultured with eye-derived fluids are the proximate antigen-presenting cells in immune deviation of the ocular type. J Immunol. 1993;151:5162-5171.