Chronic fluoxetine treatment selectively uncouples raphe 5-HT1A receptors as measured by [35S]-GTPγS autoradiography

British Journal of Pharmacology

Volumn 135, Issue 5, 2002, Pages 1115-1122

  Pejchal, Tina ^a   Foley, Melissa A ^a   Kosofsky, Barry E ^a   Waeber, Christian ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Chronic fluoxetine treatment; G protein coupling; Selective Serotonin Reuptake Inhibitors; Serotonin autoreceptors; Serotonin receptors

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 FLUORO N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDINYL)BENZAMIDE; 5 CARBAMOYLTRYPTAMINE; FLUOXETINE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 1B ANTAGONIST; SEROTONIN 1D ANTAGONIST; SEROTONIN AGONIST; SEROTONIN UPTAKE INHIBITOR; SULFUR 35; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING SITE; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; DRUG EFFICACY; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; HIPPOCAMPUS; INHIBITION KINETICS; LONG TERM EXPOSURE; MALE; MOUSE; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN INTERACTION; RECEPTOR DOWN REGULATION; SEROTONIN RELEASE; SUBSTANTIA NIGRA;

EID: 0036201126     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704555     Document Type: Article

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