Expression of telomerase activity, telomerase RNA component and telomerase catalytic subunit gene in lung cancer

Chinese Medical Journal

Volumn 115, Issue 2, 2002, Pages 290-292

  Chen, Weiwei ^a   Xiong, Xiaoxiong ^a   Zhou, Hongyuan ^a   Zhou, Qinghua ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Human telomerase reverse transcriptase; Human telomerase RNA; Lung cancer; Telomerase

Indexed keywords

RNA; RNA DIRECTED DNA POLYMERASE; TELOMERASE;

ARTICLE; CANCER GROWTH; CARCINOGENESIS; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HUMAN; HUMAN TISSUE; LUNG CANCER; LUNG PARENCHYMA; MAJOR CLINICAL STUDY; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSLATION; TELOMERIC REPEAT AMPLIFICATION PROTOCOL; TRANSCRIPTION REGULATION;

DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; TELOMERASE;

EID: 0036200125     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. The RNA component of human telomerase
2. 2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cell and during immortalization
3. Specific association of human telomerase activity with immortal cells and cancer
4. Real-time PCR quantification of human telomerase reverse transcriptase mRNA in tumors and healthy tissues
5. Human telomerase activity in immortal cell lines and tumor tissue
6. Increased expression of telomerase RNA component is associated with increased cell proliferation in human astrocytomas
7. bcl-2 modulates telomerase activity