The chemical syntheses and bioactivities of novel peptide-based endothelin antagonists

Journal of Peptide Research

Volumn 59, Issue 3, 2002, Pages 134-138

  Yu, W S ^a   Zhao, Y F ^a   Liang, Y J ^b   Liu, K L ^b,c   Fei, G S ^b   Wang, H ^b  

^a TSINGHUA UNIVERSITY   (China)

^b BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

^c Beijing Institute of Toxicology and Pharmacology   (China)

Author keywords

Aortic smooth muscle membrane; BQ 485; Endothelin; ET antagonist; ETA receptors

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN A RECEPTOR AGONIST; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; PERHYDRO 1 AZEPINYLCARBONYLLEUCYL DEXTRO TRYPTOPHYL DEXTRO TRYPTOPHAN; PHENYLALANINE; TRIPEPTIDE; TRYPTOPHAN;

ANIMAL TISSUE; AORTA; AORTA CONSTRICTION; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; IC 50; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN PURIFICATION; RAT; SMOOTH MUSCLE CONTRACTION;

ANIMALS; AORTA; AZEPINES; ENDOTHELIN-1; MUSCLE, SMOOTH, VASCULAR; OLIGOPEPTIDES; PEPTIDES; RATS; RATS, WISTAR; RECEPTOR, ENDOTHELIN A; RECEPTORS, ENDOTHELIN; STRUCTURE-ACTIVITY RELATIONSHIP; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

ANIMALIA;

EID: 0036199997     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2002.01953.x     Document Type: Article

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