Quantitative assessment of the balance between oxygen delivery and consumption in the rat brain after transient ischemia with T2-BOLD magnetic resonance imaging

Journal of Cerebral Blood Flow and Metabolism

Volumn 22, Issue 3, 2002, Pages 262-270

  Kettunen, Mikko I ^a   Gröhn, Olli H J ^a   Silvennoinen, M Johanna ^a   Penttonen, Markku ^a   Kauppinen, Risto A ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Blood oxygenation level dependent contrast; Brain; Ischemia; Luxury perfusion; MRI; T2 relaxation

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD OXYGENATION; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; BRAIN METABOLISM; BRAIN OXYGEN CONSUMPTION; BRAIN PERFUSION; CAROTID ARTERY OBSTRUCTION; COMMON CAROTID ARTERY; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN TRANSPORT; PRIORITY JOURNAL; RAT;

EID: 0036193216     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-200203000-00003     Document Type: Article

References (51)

1. 31P NMR: The cumulative effects of secondary hypoxia and ischemia
2. 1H nuclear magnetic resonance spectroscopy. Part III: Changes following ischemia
3. Brain metabolism and blood flow in acute cerebral hypoxia studied by NMR spectroscopy and hydrogen clearance
4. Quantitative measurements of cerebral blood oxygen saturation using magnetic resonance imaging
5. CBF and time thresholds for the formation of ischemic cerebral edema, and effect of reperfusion in baboons
6. Magnetic relaxation in blood and blood clots
7. Diffusion-weighted imaging studies of cerebral ischemia in gerbils: Potential relevance to energy failure
8. 2 during focal cerebral ischemia in the rat studied at 8.5 T
9. Cerebral blood flow and edema following carotid occlusion in the gerbil
10. 1H nuclear magnetic resonance spectroscopy. Part II: Changes during ischaemia
11. Calibrated functional MRI: Mapping the dynamics of oxidative metabolism
12. Real time observation of transient focal ischemia and hyperemia in cat brain
13. Nonoxidative glucose consumption during focal physiologic neural activity
14. 2: Increased precision and validation of principle
15. 2
16. 2: A theoretical and experimental approach
17. 2 on cerebral blood volume, blood flow, and vascular mean transit time
18. Quantitative T*2 and T′2 maps during reversible focal cerebral ischemia in rats: Separation of blood oxygenation from nonsusceptibility-based contributions
19. In vivo measurement of blood oxygen saturation using magnetic resonance imaging: A direct validation of the blood oxygen level-dependent concept in functional brain imaging
20. Role of PET and SPECT in the assessment of ischemic cerebrovascular disease
21. Reperfusion of the brain after global ischemia: Hemodynamic disturbances
22. 2 BOLD in assessment of cerebral misery perfusion at 1.5 T
23. 1ρ relaxation time increases immediately upon global ischemia in the rat independently of blood glucose and anoxic depolarization
24. 2 from CBF and BOLD changes: Significant increase of oxygen consumption rate during visual stimulation
25. Magnetic resonance imaging assessment of evolving focal cerebral ischemia: Comparison with histopathology in rats
26. Relationship between diffusion-weighted MR images, cerebral blood flow, and energy state in experimental brain infarction
27. Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation
28. The luxury-perfusion syndrome and its possible relation to acute metabolic acidosis localised within the brain
29. Temporal evolution of ischemic injury evaluated with diffusion-, perfusion-, and T2-weighted MRI
30. Quantitative measurements of regional cerebral blood volume using MRI in rats: Effects of arterial carbon dioxide tension and mannitol
31. 2 obtained with MRI in determining ischemic brain tissue at risk
32. Changes in energy state and acid-base parameters of the rat brain during complete compression ischemia
33. Persistent resetting of the cerebral oxygen/glucose uptake ratio by brain activation: Evidence obtained with the Kety-Schmidt technique
34. Reversible focal ischemic injury demonstrated by diffusion-weighted magnetic resonance imaging in rats
35. Brain magnetic resonance imaging with contrast dependent on blood oxygenation
36. Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging: A comparison of signal characteristics with a biophysical model
37. Determination of oxygen extraction ratios by magnetic resonance imaging
38. Venous blood effects in spin echo fMRI of human brain
39. 133Xe
40. Regional cerebral plasma volume response to carbon dioxide using magnetic resonance imaging
41. Regional cerebral blood flow and glucose metabolism following transient forebrain ischemia
42. Identification of collaterally perfused areas following focal ischemia in the rat by comparison of gradient echo and diffusion-weighted MRI
43. Continuous measurement of cerebral blood volume in rats with the photoelectric technique: Effect of morphine and naloxone
44. The distribution of normal brain water content in Wistar rats and its increase due to ischemia
45. A compartmental model for oxygen transport in brain microcirculation
46. Global ischemia in dogs: Intracranial pressures, brain blood flow and metabolism
47. Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field
48. Quantitative measurement of cerebral blood flow and cerebral blood volume after cerebral ischaemia
49. Echo-planar time course MRI of cat brain oxygenation changes
50. In vivo determination of absolute cerebral blood volume using hemoglobin as a natural contrast agent: An MRI study using altered arterial carbon dioxide tension
51. Quantitative assessment of blood flow, blood volume and blood oxygenation effects in functional magnetic resonance imaging