Selective inhibition of inducible nitric oxide synthase enhances intraglomerular coagulation in chronic anti-Thy 1 nephritis

Kidney International

Volumn 61, Issue 3, 2002, Pages 834-838

  Westenfeld, Ralf ^a,b,c   Gawlik, Alexander ^a,b,c   De Heer, Emile ^a,b,c   Kitahara, Masashi ^a,b,c   Abou Rebyeh, Faikah ^a,b,c   Floege, Juergen ^a,b,c   Ketteler, Markus ^a,b,c  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Fibrin; Glomerulonephritis; L NIL; Mesangioproliferative glomerulonephritis; Platelets; Renoprotection

Indexed keywords

ISOENZYME; MONOCLONAL ANTIBODY; N6 (1 IMINOETHYL)LYSINE; NITRIC OXIDE SYNTHASE; THY 1 ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BLOOD CLOTTING; CHRONIC GLOMERULONEPHRITIS; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; FIBRIN DEPOSITION; GLOMERULUS; MACROPHAGE; MEAN ARTERIAL PRESSURE; MICROANEURYSM; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; RAT; STAINING; THROMBOCYTE COUNT; TISSUE CULTURE; URINALYSIS; URINARY EXCRETION;

EID: 0036190205     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2002.00229.x     Document Type: Article

References (31)

1. The progression of renal disease
2. Glomeruli synthesize nitrite in experimental nephrotoxic nephritis
3. Expression and localization of inducible nitric oxide synthase in anti-thy-1 glomerulonephritis
4. Nitric oxide and glomerulonephritis
5. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase
6. Nitric oxide: Physiology, pathophysiology and pharmacology
7. Nitric oxide as a secretory product of mammalian cells
8. Glomeruli synthesize nitrite in active Heyman nephritis; the source is infiltrating macrophages
9. The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease
10. Nitric oxide mediates immunologic injury to kidney mesangium in experimental glomerulonephritis
11. Consequences of acute nitric oxide synthesis inhibition in experimental glomerulonephritis
12. Induced nitric oxide (NO) synthesis in heterologous nephrotoxic nephritis: Effects of selective inhibition in neutrophil-dependent glomerulonephritis
13. The inhibitory potency and selectivity of arginine substrate site nitric-oxide synthase inhibitors is solely determined by their affinity toward the different isoenzymes
14. Nitric oxide synthases: Structure, function and inhibition
15. Glomerulonephritis induced by monoclonal anti-Thy 1 1.1 antibodies. A sequential histological and ultrastructural analysis
16. L-arginine metabolism in immune-mediated glomerulonephritis in the rat
17. Treatment of experimental mesangioproliferative glomerulonephritis with non-anticoagulant heparin: Therapeutic efficacy and safety
18. Microplate measurements of urinary albumin and creatinine
19. Effect of dopamine receptor antagonists on the calcium dependent central function that reduces blood pressure in spontaneously hypertensive rats
20. L-arginine depletion inhibits glomerular nitric oxide synthesis and exacerbates rat nephrotoxic nephritis
21. Expression of inducible nitric oxide synthase inhibits platelet adhesion and restores blood flow in the injured artery
22. Modulation of anti-Thy1 nephritis in the rat by adenine nucleotides. Evidence for an anti-inflammatory role for nucleotidases
23. Attenuation of anti-Thy1 nephritis in the rat by anti-inflammatory platelet-inhibiting agents
24. The glomerular response to injury: Progression or resolution?
25. Tissue factor initiates glomerular fibrin deposition and promotes major histocompatibility complex class II expression in crescentic glomerulonephritis
26. The kidneys of mice with autoimmune disease acquire a hypofibrinolytic/procoagulant state that correlates with the development of glomerulonephritis and tissue microthrombosis
27. Dual regulatory effects of nitric oxide on plasminogen activator inhibitor type 1 expression in endothelial cells
28. Natriuretic factors and nitric oxide suppress plasminogen activator inhibitor-1 expression in vascular smooth muscle cells. Role of cGMP in the regulation of the plasminogen system
29. Modification of tissue factor by peroxynitrite influences its procoagulant activity
30. Expression of iNOS, eNOS and peroxynitrite modified proteins in experimental anti-myeloperoxidase associated crescentic glomerulonephritis
31. Exogenous nitric oxide prevents endotoxin-induced glomerular thrombosis in rats