Peptides with indirect in vivo activity against an intracellular pathogen: Selective lysis of infected macrophages

Journal of Peptide Research

Volumn 59, Issue 1, 2002, Pages 9-17

  Yokum, T S ^a   Hammer, R P ^a   McLaughlin, Mark L ^a   Elzer, Philip H ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

Antimicrobial peptides; Brucella abortus; In vivo activity; Infected macrophages; Intracellular pathogens; Selective lysis

Indexed keywords

CECROPIN B; GLYCINE DERIVATIVE; MELITTIN; PEPTIDE DERIVATIVE;

ALKYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; BRUCELLA ABORTUS; CONTROLLED STUDY; CYTOLYSIS; DOSE RESPONSE; DRUG ACTIVITY; DRUG SYNTHESIS; ESCHERICHIA COLI; FEMALE; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR KILLING; MACROPHAGE; MAXIMUM PERMISSIBLE DOSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; ANIMALS; ANTI-BACTERIAL AGENTS; BIOCHEMISTRY; BRUCELLA ABORTUS; BRUCELLOSIS; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PEPTIDES; STAPHYLOCOCCUS AUREUS; TRYPSIN;

ANIMALIA; BACTERIA (MICROORGANISMS); BRUCELLA; BRUCELLA MELITENSIS BIOVAR ABORTUS; ESCHERICHIA COLI; MURINAE; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 0036188725     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1397-002x.2001.10995.x     Document Type: Article

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