In vitro activity of the antimicrobial peptides human and rabbit defensins and porcine leukocyte protegrin against Mycobacterium tuberculosis

Infection and Immunity

Volumn 64, Issue 3, 1996, Pages 926-932

  Miyakawa, Yosuke ^a,e   Ratnakar, P ^a   Rao, A Gururaj ^b   Costello, Michael L ^a   Mathieu Costello, Odile ^a   Lehrer, Robert I ^c   Catanzaro, Antonino ^a,d  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b PIONEER HI BRED INTERNATIONAL INC   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UCSD MEDICAL CENTER   (United States)

^e Koga Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; DEFENSIN; MAGNESIUM; PROTEGRIN; SODIUM CHLORIDE; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIUM ISOLATION; COLONY FORMING UNIT; CONTROLLED STUDY; HOST RESISTANCE; HUMAN; HUMAN CELL; INFECTION RESISTANCE; LEUKOCYTE; MYCOBACTERIUM TUBERCULOSIS; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RABBIT; SCANNING ELECTRON MICROSCOPY; SWINE; TUBERCULOSIS;

EID: 0030043634     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.3.926-932.1996     Document Type: Article

References (44)

1. Antony, V. B., S. A. Sahn, R. N. Harada, and J. E. Repine. 1983. Lung repair and granuloma formation. Chest 83(Suppl. 1):95-96.
2. Brown, A. E., T. J. Holzer, and B. R. Anderson. 1987. Capacity of human neutrophils to kill Mycobacterium tuberculosis J. Infect. Dis. 156:985-989.
3. Crowle, A. J., R. Dahl, E. Ross, and M. H. May. 1991. Evidence that vesicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic. Infect. Immun. 30: 1823-1831.
4. Daher, K. A., M. E. Selsted, and R. I. Lehrer. 1986. Direct inactivation of viruses by human granulocyte defensins. J. Virol 60:1068-1074.
5. Denis, M. 1991. Human neutrophils, activated with cytokines or not, don't kill virulent Mycobacterium tuberculosis. J. Infect Dis 163:919-920
6. Douvas, G. S., and A. J. Crowle. 1985. Macrophages. I. Model for studying antimicrobial immunity in vitro. p. 81-90 In T Yoshida (ed.). Investigation of cell-mediated immunity. Churchill Livingstone, Inc., New York
7. Dubos, R. J., and J. G. Hirsch. 1954 The antimycobacterial activity of a peptide derived from calf thymus J Exp. Med. 99:55-64
8. Edwards, D., and C. H. Kirkpatrick. 1986. The immunology of mycobacterial diseases. Am Rev. Respir. Dis. 134:1062-1071.
9. Eisenhauer, P. B., S. S. L. Harwig, and R. I. Lehrer. 1992. Cryptidins: antimicrobial defensins of the murine small intestine. Infect. Immun 60: 3556-3565.
10. Eisenhauer, P. B., D. Szklarek, T. Ganz, and R. I. Lehrer. 1985. Activity of rabbit leukocyte peptide against Candida albicans Infect. Immun 49:202-206.
11. Frehel, C., C. Chastellier, T. Lang, and N. Rastogi. 1986 Evidence for inhibition of fusion of lysosomal and prclysosomal compartments with phagosomes in macrophages infected with pathogenic Mycobacterium avium Infect. Immun. 52:252-262.
12. Gabay, J. E. 1994 Ubiquitous natural antibiotics. Science 264:373-374.
13. Gabay, J. E., R. W. Scott, D. Campanelli, J. Griffith, C. Wilde, M. N. Marra, M. Seeger, and C. F. Nathan. 1989. Antibiotic protein of human polymorphonuclear leukocytes. Proc Natl. Acad Sci. USA 86:5610-5614.
14. Ganz, T. 1987. Extracellular release of antimicrobial defensins by human polymorphonuclear leukocytes. Infect. Immun. 55:568-571.
15. Ganz, T., M. E. Selsted, and R. I. Lehrer. 1990. Defensins. Eur. J. Haematol. 44:1-8.
16. Ganz, T., M. E. Szklarek, S. S. L. Harwig, K. Daher, D. F. Bainton, and R. I. Lehrer. 1985. Defensins. Natural peptide antibiotics of human neutrophils. J Clin. Invest. 76:1427-1435.
17. Goble, M., M. D. Iseman, L. A. Madsen, D. Waite, L. Ackerson, and C. R. Horsburgh. 1993. Treatment of 171 patients, with pulmonary tuberculosis resistant to isoniazid and rifampin. N. Engl. J. Med. 328:527-532.
18. Heifets, L. B., M. D. Iseman, and P. J. Lindholm-Levy. 1985. Determination of ansamycin MICs for Mycobacterium avium complex in liquid medium by radiometric and conventional methods. Antimicrob. Agents Chemother 28: 955-957.
19. Heifets, L. B., M. D. Iseman, and P. J. Lindholm-Levy. 1986. Ethambutal MICs and MBCs for Mycobacterium avium complex and Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 30:927-932
20. Hiemstra, P. S., P. B. Eisenhauer, S. S. L. Harwig, M. T. Barselaar, R. Furth, and R. I. Lehrer. 1993. Antimicrobial proteins of murine macrophages. Infect. Immun. 61:3038-3046.
21. Inderlied, C. B., L. S. Young, and J. K. Yumada. 1987. Determination of in vitro susceptibility of Mycobacterium avium complex isolates to antimycobacterial agents by various methods. Antimicrob. Agents Chemother. 31:1697-1702.
22. Jones, G. S., H. J. Amirault, and B. R. Anderson. 1990. Killing of Mycobacterium tuberculosis by neutrophils: a nonoxidative process. J. Infect. Dis 162: 700-704.
23. Kokryakov, V. N., S. S. L. Harwig, E. A. Panyutich, A. A. Shevchenko, G. M. Aleshina, O. V. Shamova, H. A. Korneva, and R. I. Lehrer. 1993 Protegrins: leukocyte antimicrobial peptides that combine features of corticostatic defensins and tachyplesins. FEBS Lett. 327:231-236.
24. Lehrer, R. I., A. Barton, K. A. Daher, S. S. L. Harwig, T. Ganz, and M. E. Selsted. 1989. Interaction of human defensins with Escherichia coli: mechanism of bactericidal activity. J. Clin. Invest. 84:553-561.
25. Lehrer, R. I., and T. Ganz. 1990. Antimiciobial polypeptides of human neutrophil. Blood 76:2169-2181.
26. Lehrer, R. I., T. Ganz, D. Szklarek, and M. E. Selsted. 1988. Modulation of the in vitro candidacidal activity of human neutrophil defensins by target cell metabolism and divalent cations. J. Clin. Invest. 81:1829-1835.
27. Lehrer, R. I., A. K. Lichtenstein, and T. Ganz. 1993 Defensins. antimicrobial and cytotoxic peptides of mammalian cells Annu. Rev Immunol. 11:105-128.
28. Lehrer, R. I., M. Rosenman, S. S. L. Harwig, R. Jackson, and P. Eisenhauer. 1991. Ultrasensitive assays for endogenous antimicrobial polypeptides. J. Immunol. Methods 137:167-173
29. MaKaness, G. B. 1952. The action of drugs on intracellular tubercle bacilli. J. Pathol. Bacteriol. 64:429-446.
30. May, M. E., and P. J. Spagnolo. 1987 Evidence for activation of a respiratory burst in the interaction of human neutrophils with Mycobacterium tuberculosis Infect. Immun. 55:2304-2307.
31. Montgomery, L. G., and W. Lemon. 1933. The cellular reaction of the pleura to infection with Mycobacterium tuberculosis. J. Thorac. Cardiovasc. Surg. 2: 429-438.
32. Murray, C. J., K. Styblo, and A. Rouillon. 1990. Tuberculosis in developing countries: burden, intervention and cost. Bull. Int. Union Tuberc. 65:6-14
33. Ogata, K., B. A. Linzer, R. I. Zuberi, T. Ganz, R. I. Lehrer, and A. Catanzaro. 1992. Activity of defensins from human neutrophilic granulocytes against Mycobacterium avium-Mycobacterium intracellulare. Infect. Immun 60:4720-4725.
34. Oshima, S., Q. N. Myrvik, and E. Leake. 1961 The demonstration of lysozyme as a dominant tuberculostatic factor in extracts of granulomatous lungs. Br. J. Exp. Pathol. 42:138-144.
35. Rao, A. G., T. Rood, J. Maddox, and J. Duvick. 1992. Synthesis and characterization of defensin NP-1 Int J Peptide Protein Res. 40:507-514.
36. Rous, P. 1924. The relative reaction within living mammalian tissues. II On the mobilization of acid material within cells and the reaction as influenced by the cell state. J. Exp. Med 41:399-412
37. Selsted, M. E., and S. S. L. Harwig. 1987. Purification, primary structure, and antimicrobial activities of a guinea pig neutrophil defensin Infect. Immun. 55:2281-2286.
38. 37a.Selsted, M. E., D. Szklarek, and R. I. Lehrer. 1984 Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes. Infect. Immun. 45-150-154.
39. Shimoda, M., K. Ohki, Y. Shimamoto, and O. Kohashi. 1995. Morphology of defensin-treated Staphylococcus aureus. Infect. Immun. 63:2886-2891.
40. Silva, M. T., M. N. T. Silvia, and R. Appelberg. 1989. Neutrophil-macrophage cooperation in the host defense against mycobacterial infections. Microb. Pathog. 6:369-380.
41. Smith, C. C., R. M. Barr, and J. H. Alexander. 1979. Studies on the interaction of Mycobacterium microti and M. lepraemurium with mouse polymorphonuclear leukocytes. J. Gen. Microbiol. 112:185-189.
42. Territo, M. C., T. Ganz, M. E. Selsted, and R. I. Lehrer. 1989. Monocytechemotactic activity of defensins from human neutrophils. J. Clin. Invest. 84: 201-202
43. Zeya, H. I., and J. K. Spitznagel. 1963. Antibacterial and enzymic basic proteins from leukocyte lysosomes: separation and identification. Science 142:1085-1087.
44. Zeya, H. I., and J. K. Spitznagel. 1966. Cationic proteins of polymorphonuclear leukocyte lysozyme. I. Resolution of antibacterial and enzymatic activities. J. Bacteriol 91:750-754.