Methoxychlor stimulates the mouse lactoferrin gene promoter through a GC-rich element

Biochemistry and Cell Biology

Volumn 80, Issue 1, 2002, Pages 23-26

  Zhang, Zhiping ^a   Teng, Christina T ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Environmental; Lactoferrin gene; Methoxychlor; Promoter; Xenoestrogen

Indexed keywords

GENES; METABOLITES; PROTEINS;

UTERUS;

BIOCHEMISTRY;

1,1,1 TRICHLORO 2,2 BIS(4 HYDROXYPHENYL)ETHANE; BENZENE DERIVATIVE; CHLORAMPHENICOL ACETYLTRANSFERASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYSTEINE; EPIDERMAL GROWTH FACTOR; GLYCINE; LACTOFERRIN; METHOXYCHLOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; CANCER CELL CULTURE; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; DNA FLANKING REGION; DNA TRANSFECTION; ENDOMETRIUM CARCINOMA; ENZYME ACTIVITY; GENE ACTIVATION; HUMAN; HUMAN CELL; METABOLITE; MOUSE; NONHUMAN; PROMOTER REGION;

ANIMALS; BASE SEQUENCE; HUMANS; LACTOFERRIN; METHOXYCHLOR; MICE; PROMOTER REGIONS (GENETICS); RESPONSE ELEMENTS; TRANS-ACTIVATION (GENETICS); TRANSFECTION; TUMOR CELLS, CULTURED;

FELIS CATUS;

EID: 0036188003     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o01-177     Document Type: Conference Paper

References (23)

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4. Studies on the in vivo and in vitro estrogenic activities of methoxychlor and its metabolites. Role of hepatic mono-oxygenase in methoxychlor activation
5. Methoxychlor as a model for environmental estrogens
6. Mechanisms of the stimulation of rat uterine peroxidase activity by methoxychlor
7. Effects of estrogen, progesterone, and methoxychlor on surgically induced endometriosis in rats
8. Estrogenic responses in estrogen receptor-alpha deficient mice reveal a distinct estrogen signaling pathway
9. Differential spatiotemporal regulation of lactoferrin and progesterone receptor genes in the mouse uterus by primary estrogen, catechol estrogen, and xenoestrogen
10. Estradiol or methoxychlor stimulates estrogen receptor (ER) expression in uteri
11. Differential interaction of the methoxychlor metabolite 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane with estrogen receptors alpha and beta
12. Methoxychlor stimulates estrogen-responsive messenger ribonucleic acids in mouse uterus through a non-estrogen receptor (non-ER) alpha and non-ER beta mechanism
13. The estrogenic and antiandrogenic pesticide methoxychlor alters the reproductive tract and behavior without affecting pituitary size or LH and prolactin secretion in male rats
14. Characterization of estrogen-responsive mouse lactoferrin promoter
15. Lactotransferrin is the major estrogen inducible protein of mouse uterine secretions
16. Assessing environmental chemicals for estrogenicity using a combination of in vitro and in vivo assays
17. Promoter-specific activation of mouse lactoferrin gene by epidermal growth factor involves two adjacent regulatory elements
18. Characterization of a mitogen-response unit in the mouse lactoferrin gene promoter
19. Isolation and characterization of a gene encoding human Kruppel-like factor 5 (IKLF): Binding to the CAAT/GT box of the mouse lactoferrin gene promoter
20. Response of adult murine uterine epithelium to 50% methoxychlor
21. Regulation of lactoferrin gene expression by estrogen and epidermal growth factor - Molecular mechanism
22. Purification and properties of an oestrogen-stimulated mouse uterine glycoprotein (approx. 70 kDa)
23. Lactotransferrin gene expression in the mouse uterus and mammary gland