The positive role of the carboxyl terminus of the γ subunit of retinal cGMP-phosphodiesterase in maintaining phosphodiesterase activity in vivo

Vision Research

Volumn 42, Issue 4, 2002, Pages 439-445

  Tsang, Stephen H ^a   Yamashita, Clyde K ^a   Lee, Won Ho ^a   Lin, Chyuan Sheng ^c   Goff, Stephen P ^c   Gouras, Peter ^d   Farber, Debora B ^a,b  

^a JULES STEIN EYE INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NONE   (United States)

^d New York Presbyterian Hospital   (United States)

Author keywords

Knockout animals; Phosphodiesterase; Photoreceptor transduction; Retinal degeneration; Transgenic animals

Indexed keywords

AMINO ACID; CYCLIC GMP PHOSPHODIESTERASE; MUTANT PROTEIN; PHOSPHODIESTERASE; PROTEIN SUBUNIT;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DARKNESS; DELETION MUTANT; ENZYME ACTIVITY; IN VIVO STUDY; KNOCKOUT MOUSE; LIGHT; MOUSE; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RETINA; TISSUE LEVEL; TRANSGENIC MOUSE;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; ANIMALS; ELECTRORETINOGRAPHY; MICE; MICE, TRANSGENIC; MUTATION; PHOSPHORIC DIESTER HYDROLASES; RETINA; RETINAL DEGENERATION; TERMINAL REPEAT SEQUENCES;

EID: 0036183704     PISSN: 00426989     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0042-6989(01)00213-9     Document Type: Article

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