The γ subunit of rod cGMP-phosphodiesterase blocks the enzyme catalytic site

Journal of Biological Chemistry

Volumn 272, Issue 18, 1997, Pages 11686-11689

  Granovsky, Alexey E ^a   Natochin, Michael ^a   Artemyev, Nikolai O ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 BROMO CYCLIC GMP; CYCLIC GMP DERIVATIVE; CYCLIC GMP PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; ZAPRINAST;

ANIMAL CELL; ARTICLE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBUNIT; NONHUMAN; PHOTORECEPTOR CELL; PRIORITY JOURNAL; RETINA ROD; SIGNAL TRANSDUCTION; VERTEBRATE; VISUAL SYSTEM;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; ANIMALS; BINDING SITES; CATTLE; CELL MEMBRANE; COUMARINS; CYCLIC GMP; CYSTEINE; FLUORESCENT DYES; KINETICS; MACROMOLECULAR SUBSTANCES; PHOSPHODIESTERASE INHIBITORS; POINT MUTATION; PURINONES; ROD OUTER SEGMENTS; SERINE; VERTEBRATES;

EID: 0030972213     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.18.11686     Document Type: Article

References (25)

1. Chabre, M., and Deterre, P. (1989) Eur. J. Biochem. 179, 255-266
2. Hargrave, P. A., Hamm, H. E., and Hofmann, K. P. (1993) Bioessays 15, 43-50
3. Yarfitz, S., and Hurley, J. B. (1994) J. Biol. Chem. 269, 14329-14332
4. Stryer, L. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 557-559
5. Lipkin, B. M., Dumler, I. L., Muradov, K. G., Artemyev, N. O., and Etingof, R. N. (1988) FEBS Lett. 234, 287-290
6. Artemyev, N. O., and Hamm, H. E. (1992) Biochem. J. 283, 273-279
7. Takemoto, D. J., Hurt, D., Oppert, B., and Cunnick, J. (1992) Biochem. J. 281, 637-643
8. Brown, R. L. (1992) Biochemistry 31, 5918-5925
9. Skiba, N. P., Artemyev, N. O., and Hamm, H. E. (1995) J. Biol. Chem. 270, 13210-13215
10. Artemyev, N. O., Natochin, M., Busman, M., Schey, K. L., and Hamm, H. E. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 5407-5412
11. Papermaster, D. S., and Dreyer, W. J. (1974) Biochemistry 13, 2438-2444
12. Baehr, W., Devlin, M. J., and Applebury, M. L. (1979) J. Biol. Chem. 254, 11669-11677
13. Natochin, M., and Artemyev, N. O. (1996) J. Biol. Chem. 271, 19964-19969
14. Liebman, P. A., and Evanczuk, A. T. (1982) Methods Enzymol. 81, 532-542
15. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
16. Laemmli, U. K. (1970) Nature 227, 680-685
17. Hurley, J. B., and Stryer, L. (1982) J. Biol. Chem. 257, 11094-11099
18. Catty, P., and Deterre, P. (1991) Eur. J. Biochem. 199, 263-269
19. Gillespie, P. G., and Beavo, J. A. (1989) Mol. Pharmacol. 36, 773-781
20. McAllister-Lucas, L. M., Sonnenburg, W. K., Kadlecek, A., Seger, D., Trong, H. L., Colbran, J. L., Thomas M. K., Walsh, K. A., Francis, S. H., Corbin, J. D., and Beavo, J. A. (1993) J. Biol. Chem. 268, 22863-22873
21. Beltman, J., Becker, D., Butt, E., Jensen, G. S., Rybalkin, S. D., Jastorff., and Beavo, J. A. (1995) Mol. Pharmacol. 47, 330-339
22. Wensel, T. G., and Stryer, L. (1990) Biochemistry 29, 2155-2161
23. Gillespie, P. G., and Beavo, J. A. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 4311-4315
24. Jurnak, F. (1988) Trends Biochem. Sci. 13, 196-198
25. Noel, J. P., Hamm, H. E., and Sigler, P. B. (1993) Nature 366, 654-663