New isoxazole derivatives designed as nicotinic acetylcholine receptor ligand candidates

European Journal of Medicinal Chemistry

Volumn 37, Issue 2, 2002, Pages 163-170

  Silva, Nilda M ^a   Tributino, Jorge L M ^a   Miranda, Ana L P ^a   Barreiro, Eliezer J ^a   Fraga, Carlos A M ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Analgesic activity; Epibatidine; Isoxazole derivatives; Molecular hybridization; Nicotinic receptor ligand

Indexed keywords

2 (3 METHYL 5 ISOXAZOLYL)PYRIDINE; ESTER; ISOXAZOLE DERIVATIVE; LIGAND; MECAMYLAMINE; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; FEMALE; HOT PLATE TEST; MALE; MOUSE; NONHUMAN;

ANALGESICS; ANIMALS; DRUG EVALUATION, PRECLINICAL; FEMALE; ISOXAZOLES; LIGANDS; MALE; MICE; MOLECULAR STRUCTURE; NICOTINIC ANTAGONISTS; RECEPTORS, NICOTINIC; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036178336     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(01)01327-7     Document Type: Article

References (25)