Nicotinic cholinergic receptors: Potential targets for inflammatory pain relief

Pain

Volumn 80, Issue 1-2, 1999, Pages 291-299

  Lawand, Nada B ^a   Lu, Ying ^a   Westlund, Karin N ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Epibatidine; Hyperalgesia; Inflammation; Joint pain; Nicotinic Receptors

Indexed keywords

CARRAGEENAN; EPIBATIDINE; KAOLIN; MECAMYLAMINE; NICOTINIC AGENT; NICOTINIC RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTHRITIS; BEHAVIOR; CONTROLLED STUDY; DRUG ACTIVITY; HYPERALGESIA; INFLAMMATION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; NEUROGENIC INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; RAT; REVIEW; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0032995466     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(98)00221-8     Document Type: Article

References (52)

1. Aceto, M.D., Awaya, H., Martin, B.R. and May, E.L., Antinociceptive action of nicotine and its methiodide derivatives in mice and rats, Br. J. Pharmacol., 79 (1983) 869-876.
2. Attal, N., Jazat, F., Kayser, V. and Guilbaud, G., Further evidence for 'pain-related' behaviors in a model of unilateral peripheral mononeuropathy, Pain, 41 (1990) 235-251.
3. Badio, B. and Daly, J.W., Epibatidine, a potent analgetic and nicotinic agonist, Mol. Pharmacol., 45 (1994) 563-569.
4. Bannon, A.W., Decker, M.W., Holladay, M.W., Curzon, P., Donnelly-roberts, D., Puttfarcken, P.S., Bitner, R.S., Diaz, A., Dickenson, A.H., Porsolt, R.D., Williams, M. and Arneric, S.P., Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors, Science, 279 (1998) 77-81.
5. Barber, R.P., Phelps, P.E., Houser, C.R., Crawford, G.D., Salvaterra, P.M. and Vaughn, J.E., The morphology and distribution of neurons containing choline acetyltransferase in the adult rat spinal cord: an immunohistochemical study, J. Comp. Neurol., 229 (1984) 329-346.
6. Bonhaus, D.W., Bley, K.R., Broka, C.A., Fontana, D.J., Leung, E., Lewis, R., Shieh, A. and Wong, E.H., Characterization of the electrophysiological, biochemical and behavioral actions of epibatidine, J. Pharmacol. Exp. Ther., 272 (1995) 1199-1203.
7. Borges, L.F. and Iversen, S.D., Topography of choline acetyltransferase immunoreactive neurons and fibers in the rat spinal cord, Brain Res., 362 (1986) 140-148.
8. Bowker, R.M., Westlund, K.N., Sullivan, M.C., Wilber, J.F. and Coulter, J.D., Descending serotonergic, peptidergic and cholinergic pathways from the raphe nuclei: a multiple transmitter complex, Brain Res., 288 (1983) 33-48.
9. Castro-Lopes, J.M., Tavares, I., Tolle, T.R. and Coimbra, A., Carrageenan-induced inflammation of the hind foot provokes a rise of GABA-immunoreactive cells in the rat spinal cord that is prevented by peripheral neurectomy or neonatal capsaicin treatment, Pain, 56 (1994) 193-201.
10. Damaj, M.I. and Martin, B.R., Tolerance to the antinociceptive effect of epibatidine after acute and chronic administration in mice, Eur. J. Pharmacol., 300 (1996) 51-57.
11. Dhatt, R.K., Gudehithlu, K.P., Wemlinger, T.A., Tejwani, G.A., Neff, N.H. and Hadjiconstantinou, M., Preproenkephalin mRNA and methionine-enkephalin content are increased in mouse striatum after treatment with nicotine, J. Neurochem., 64 (1995) 1878-1883.
12. Dickenson, A.H., Chapman, V. and Green, G.M., The pharmacology of excitatory and inhibitory amino acid-mediated events in the transmission and modulation of pain in the spinal cord, Gen. Pharmacol., 28 (1997) 633-638.
13. Dirig, D.M. and Yaksh, T.L., Intrathecal baclofen and muscimol, but not midazolam, are antinociceptive using the rat-formalin model, J. Pharmacol. Exp. Ther., 275 (1995) 219-227.
14. Gerzanich, V., Peng, F., Wang, F., Wells, G., Anand, R., Fletcher, S. and Lindstrom, J., Comparative pharmacology of epibatidine: a potent agonist for neuronal nicotinic acetylcholine receptors, Mol. Pharmacol., 48 (1995) 774-782.
15. 3H] acetylcholine binding sites in the cervical spinal cord of man and some other species, Neurosci. Lett., 90 (1988) 197-202.
16. Hargreaves, K., Dubner, R., Brown, F., Flores, C. and Joris, J., New and sensitive method for measuring thermal nociception in cutaneous hyperalgesia, Pain, 32 (1988) 77-88.
17. Henry, J.L., Substance P and inflammatory pain: potential of substance P antagonists as analgesics, Agents Actions, 41 (1993) 75-87.
18. Houser, C.R., Crawford, G.D., Barber, R.P., Salvaterra, P.M. and Vaughn, J.E., Organization and morphological characteristics of cholinergic neurons: an immunocytochemical study with a monoclonal antibody to choline acetyltransferase, Brain Res., 266 (1983) 97-119.
19. Jones, A.K., Cunningham, V.J., Ha-Kawa, S., Fujiwara, T., Luthra, S.K., Silva, S., Derbyshire, S. and Jones, T., Changes in central opioid receptor binding in relation to inflammation and pain in patients with rheumatoid arthritis, Br. J. Rheumatol., 33 (1994) 909-916.
20. Kaneko, M. and Hammond, D.L., Role of spinal gamma-aminobutyric acid A receptors in formalin-induced nociception in the rat, J. Pharmacol. Exp. Ther., 282 (1997) 928-938.
21. Kayser, V., Guilbaud, G. and Benoist, J.M., Modifications of the opioid system reactivity in Freund's adjuvant induced-arthritic and carrageenan-injected rats, models or chronic and acute inflammatory pain: behavioural and electrophysiological studies, Agents Actions, 23 (1988) 27-28.
22. Khan, I.M., Marsala, M., Printz, M.P., Taylor, P. and Yaksh, T.L., Intrathecal nicotinic agonist-elicited release of excitatory amino acids as measured by in vivo spinal microdialysis in rats, J. Pharmacol. Exp. Ther., 278 (1996) 97-106.
23. Khan, I.M., Yaksh, T.L. and Taylor, P., Ligand specificity of nicotinic acetylcholine receptors in rats spinal cord: studies with nicotine and cytisine, J. Pharmacol. Exp. Ther., 270 (1994) 159-166.
24. Laing, I., Todd, A.J., Heizmann, C.W. and Schmidt, H.H., Subpopulations of GABAergic neurons in laminae I-III of rat spinal dorsal horn defined by coexistence with classical transmitters, peptides, nitric oxide synthase or parvalbumin, Neuroscience, 61 (1994) 123-132.
25. Miao, F.J., Benowitz, N.L., Heller, P.H. and Levine, J.D., Contribution of adrenal hormones to nicotine-induced inhibition of synovial plasma extravasation in the rat, Br. J. Pharmacol., 120 (1997) 298-304.
26. Millan, M.J. and Colpaert, F.C., Opioid systems in the response to inflammatory pain: sustained blockade suggests role of kappa- but not muopioid receptors in the modulation of nociception, behaviour and pathology, Neuroscience, 42 (1991) 541-553.
27. Morita, K. and Katayama, Y., Two types of acetylcholine receptors on the soma of primary afferent neurons, Brain Res., 290 (1984) 348-352.
28. Neugebauer, V., Lucke, T. and Schaible, H.G., N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists block the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint, J. Neurophysiol., 70 (1993) 1365-1377.
29. Ohkubo, T., Shibata, M., Takahashi, H. and Inoki, R., Roles of substance P and somatostatin on transmission of nociceptive information induced by formalin in spinal cord, J. Pharmacol. Exp. Ther., 252 (1990) 1261-1268.
30. Puttfarcken, P.S., Manelli, A.M., Arneric, S.P. and Donnelly-Roberts, D.L., Evidence for nicotinic receptors potentially modulating nociceptive transmission at the level of the primary sensory neuron: studies with F11 cells, J. Neurochem., 69 (1997) 930-938.
31. Rao, T.S., Correa, L.D., Reid, R.T. and Lloyd, G.K., Evaluation of antinociceptive effects of neuronal nicotinic acetylcholine receptor (NAChR) ligands in the rat-tail flick assay, Neuropharmacology, 35 (1996) 393-405.
32. Rees, H., Sluka, K.A., Westlund, K.N. and Willis, W.D., Do dorsal root reflexes augment peripheral inflammation? NeuroReport, 5 (1994) 821-824.
33. Rees, H., Sluka, K.A., Westlund, K.N. and Willis, W.D., The role of glutamate and GABA receptors in the generation of dorsal root reflexes by acute arthritis in the anaesthetized rat, J. Physiol., 484 (1995) 437-445.
34. Ribeiro-da-Silva, A. and Cuello, A.C., Choline acetyltransferase-immunoreactive profiles are presynaptic to primary sensory fibers in the rat superficial dorsal horn, J. Comp. Neurol., 295 (1990) 370-384.
35. Roberts, R.G., Stevenson, J.E., Westerman, R.A. and Pennefather, J., Nicotinic acetylcholine receptors on capsaicin-sensitive nerves, NeuroReport, 6 (1995) 1578-1582.
36. Sacaan, A.I., Menzaghi, F., Dunlop, J.L., Correa, L.D., Whelan, K.T. and Lloyd, G.K., Epibatidine: a nicotinic acetylcholine receptor agonist releases monoaminergic neurotransmitters: in vitro and in vivo evidence in rats, J. Pharmacol. Exp. Ther., 276 (1996) 509-515.
37. Sershen, H., Balla, A., Lajtha, A. and Vizi, E.S., Characterization of nicotinic receptors involved in the release of noradrenaline from the hippocampus, Neuroscience, 77 (1997) 121-130.
38. Sluka, K.A. and Westlund, K.N., An experimental arthritis in rat: dorsal horn aspartate and glutamate increases, Neurosci. Lett., 145 (1992) 141-144.
39. Sluka, K.A. and Westlund, K.N., Behavioral and immunohisto-chemical changes in an experimental arthritis model in rats, Pain, 55 (1993a) 367-377.
40. Sluka, K.A. and Westlund, K.N., Spinal cord amino acid release and content in an arthritis model: the effects of pretreatment with non-NMDA, NMDA, and NK1 receptor antagonists, Brain Res., 627 (1993b) 89-103.
41. Sluka, K.A. and Westlund, K.N., An experimental arthritis model in rats: the effects of NMDA and non-NMDA antagonists on aspartate and glutamate release in the dorsal horn, Neurosci. Lett., 149 (1993c) 99-102.
42. B receptor antagonists in rats, J. Pharmacol. Ther., 271 (1994a) 76-82.
43. Sluka, K.A., Jordan, H.H., Willis, W.D. and Westlund, K.N., Differential effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on spinal release of amino acids after development of acute arthritis in rats, Brain Res., 664 (1994b) 77-84.
44. Sluka, K.A., Willis, W.D. and Westlund, K.A., The role of dorsal root reflexes in neurogenic inflammation, Pain Forum, 4 (1995) 141-149.
45. Spande, T.F., Garrafo, H.M., Edwards, M.W., Yeh, H.J.C., Pannel, L. and Daley, J.W., Epibatidine: a novel (chloropyridyl) azabicyclo-heptane with potent analgesic activity from a Ecuadorian poison frog, J. Am. Chem. Soc., 114 (1992) 3475-3480.
46. Todd, A.J., Immunohistochemical evidence that acetylcholine and glycine exist in different populations of GABAergic neurons in lamina III of rat spinal dorsal horn, Neuroscience, 44 (1991) 741-746.
47. Traub, R.J., The spinal contribution of substance P to the generation and maintenance of inflammatory hyperalgesia in the rat, Pain, 67 (1996) 151-161.
48. Urban, L., Thompson, S.W. and Dray, A., Modulation of spinal excitability: co-operation between neurokinin and excitatory amino acid neurotransmitters, Trends Neurosci., 17 (1994) 432-438.
49. Weihe, E., Nohr, D., Millan, M.J., Stein, C., Muller, S., Gramsch, C. and Herz, A., Peptide neuroanatomy of adjuvant-induced arthritic inflammation in rat, Agents Actions, 25 (1988) 255-259.
50. Westfall, T.C., Grant, H. and Perry, H., Release of dopamine and 5-hydroxytryptamine from rat striatal slices following activation of nicotinic cholinergic receptors, Gen. Pharmacol., 14 (1983) 321-325.
51. 3H]noradrenaline and adenosine from slices of rat hippocampus and parietal cortex, Neurosci. Lett., 235 (1997) 125-128.
52. Willcockson, W.S., Chung, J.M., Hori, Y., Lee, K.H. and Willis, W.D., Effects of iontophoretically released amino acids and amines on primate spinothalamic tract cells, J. Neurosci., 4 (1984) 732-740.