Agmatine, an endogenous ligand at imidazoline binding sites, does not antagonize the clonidine-mediated blood pressure reaction

British Journal of Pharmacology

Volumn 135, Issue 3, 2002, Pages 663-672

  Raasch, Walter ^a   Schäfer, Ulrich ^a   Qadri, Fatimunnisa ^a   Dominiak, Peter ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

Agmatine; Blood pressure; Clonidine; Clonidine displacing substance; Heart rate; Imidazoline binding sites; Noradrenaline release; Spontaneously hypertensive rats; Sympathetic tone

Indexed keywords

ADRENALIN; AGMATINE; AGN 192403; ALPHA 2 ADRENERGIC RECEPTOR; CLONIDINE; CLONIDINE DISPLACING SUBSTANCE; IMIDAZOLINE I1 RECEPTOR; NORADRENALIN; PHENOXYBENZAMINE; PHENYLEPHRINE; UNCLASSIFIED DRUG; VASOACTIVE AGENT;

ADRENALIN RELEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; AORTA MEDIA; ARTICLE; BLOOD PRESSURE REGULATION; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DRUG ANTAGONISM; DRUG HALF LIFE; HEART RATE; HYPERTENSION; LETHAL DOSE; MALE; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTILITY; SPONTANEOUSLY HYPERTENSIVE RAT; SYMPATHETIC TONE;

EID: 0036177993     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704513     Document Type: Article

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