An efficient synthesis of orthogonally protected spermidine

Synthetic Communications

Volumn 32, Issue 3, 2002, Pages 319-328

  Amssoms, K ^a   Augustyns, K ^a   Yamani, A ^a   Zhang, M ^a   Haemers, A ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPROPANOL; N 8 BENZYLOXYCARBONYL N 1 TERT BUTYLOXYCARBONYL N 4 (2 NITROBENZENESULFONYL)SPERMIDINE; PROPANOL; PUTRESCINE; SPERMIDINE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; SYNTHESIS;

EID: 0036174876     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1081/SCC-120002114     Document Type: Article

References (12)

1. Trypanothione: A novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids
2. Preparation of diamino ethers and polyamines
3. An efficient synthesis of selectively functionalized spermidine
4. Synthesis of threo-cis/threo-trans and erythro-cis/erythro-trans-dihydropalustrin
5. Reagents for the stepwise functionalization of spermidine, homospermidine bis(3-aminopropyl)amine
6. Solid phase synthesis of polyamine conjugates for the study of trypanothione reductase
7. Facile synthesis of polyamine conjugates utilising selectively protected polyamines immobilised on solid phase
8. Solid-phase synthesis of symmetrical and unsymmetrical polyamine analogues of philanotoxins using a Dde-linker
9. 2- and 4-nitrobenzenesulfonamides: Exceptionally versatile means for preparation of secondary amines and protection of amines
10. Total synthesis of polyamine toxin HO-416b. Utilizing the 2-nitrobenzenesulfonamide protecting group
11. Novel inhibitors of trypanothione biosynthesis: Synthesis and evaluation of a phosphinate analog of glutathionyl spermidine (GSP), a potent, slow-binding inhibitor of GSP synthetase
12. Investigations on new strategies for the facile synthesis of polyfunctionalized phospinates: Phosphinopeptide analogues of glutathionylspermidine