Cytosines do it, thymines do it, even pseudouridines do it - Base flipping by an enzyme that acts on RNA

Structure

Volumn 10, Issue 2, 2002, Pages 127-129

  Cheng, Xiaodong ^a   Blumenthal, Robert M ^b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE DERIVATIVE; DNA; PSEUDOURIDINE; THYMINE DERIVATIVE; TRANSFER RNA;

DNA STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME STRUCTURE; EXPERIMENTAL MODEL; PRIORITY JOURNAL; RNA STRUCTURE; SHORT SURVEY;

EID: 0036174763     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(02)00710-4     Document Type: Review

References (10)

1. HhaI methyltransferase flips its target base out of the DNA helix
2. Base flipping
3. Crystal structure of a hairpin ribozyme-inhibitor complex with implications for catalysis
4. Rearrangement of a stable RNA secondary structure during VS ribozyme catalysis
5. Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
6. Crystal structures of restrictocin-inhibitor complexes with implications for RNA recognition and base flipping
7. Crystal structure of an initiation factor bound to the 30S ribosomal subunit
8. The mechanism of pseudouridine synthase I as deduced from its interaction with 5-fluorouracil-tRNA
9. Cocrystal structure of a tRNA 55 pseudouridine synthase: Nucleotide flipping by an RNA-modifying enzyme
10. A second function for pseudouridine synthases: A point mutant of RluD unable to form pseudouridines 1911, 1915, and 1917 in Escherichia coli 23S ribosomal RNA restores normal growth to an RluD-minus strain