Aminated gelatin as a nasal absorption enhancer for peptide drugs: Evaluation of absorption enhancing effect and nasal mucosa perturbation in rats

Journal of Pharmacy and Pharmacology

Volumn 54, Issue 2, 2002, Pages 181-188

  Wang, J ^a,b   Sakai, S ^a   Deguchi, Y ^a   Bi, D ^b   Tabata, Y ^c   Morimoto, K ^a  

^a HOKKAIDO INSTITUTE OF TECHNOLOGY   (Japan)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GELATIN; GLUCOSE; INSULIN; LACTATE DEHYDROGENASE; PEPTIDE DERIVATIVE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG FORMULATION; DRUG POTENTIATION; DRUG TRANSPORT; GLUCOSE BLOOD LEVEL; HYPOGLYCEMIA; ISOELECTRIC POINT; LEACHING; MALE; MOLECULAR WEIGHT; NONHUMAN; NOSE MUCOSA; PERFUSION; PH; RAT;

ABSORPTION; ADMINISTRATION, INTRANASAL; AMINATION; ANIMALS; BLOOD GLUCOSE; DEXTRANS; DRUG CARRIERS; FLUORESCEIN-5-ISOTHIOCYANATE; GELATIN; INSULIN; L-LACTATE DEHYDROGENASE; MALE; NASAL MUCOSA; PEPTIDES; RATS; RATS, WISTAR;

EID: 0036174537     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357021778367     Document Type: Article

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