Electroporation-mediated tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/Apo2L gene therapy for hepatocellular carcinoma

Human Gene Therapy

Volumn 13, Issue 2, 2002, Pages 275-286

  Yamashita, Yo Ichi ^a   Shimada, Mitsuo ^a   Tanaka, Shinji ^a   Okamamoto, Masahiro ^a   Miyazaki, Jun Ichi ^b   Sugimachi, Keizo ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; ELECTROPORATION; FEMALE; GENE THERAPY; IMMUNOCOMPETENCE; IN VIVO STUDY; LIVER CELL CARCINOMA; LUNG METASTASIS; MOUSE; NICK END LABELING; NONHUMAN;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CARCINOMA, HEPATOCELLULAR; ELECTROPORATION; FEMALE; GENE THERAPY; LUNG NEOPLASMS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C3H; NEOPLASM METASTASIS; PRECIPITIN TESTS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0036173712     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430340252769798     Document Type: Article

References (35)

1. The complexity of TNF-related apoptosis-inducing ligand
2. Gene transfer into muscle by electroporation in vivo
3. Introduction and expression of DNA molecules in eukaryotic cells by electroporation
4. Transplantation of hepatomas in mice
5. Safety and antitumor activity of recombinant soluble Apo2 ligand
6. Mechanisms of hepatic toxicity. I. TNF-induced liver injury
7. A family of ligands for the TNF receptor superfamily
8. Current treatment modalities for hepatocellular carcinoma
9. High efficient electro-gene therapy of solid tumor by using an expression plasmid for the herpes simplex virus thymidine kinase gene
10. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
11. Adenoviral-mediated transfer of the TNF-related apoptosis-inducing ligand/Apo-2 ligand gene induces tumor cell apoptosis
12. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
13. Molecular determinants of response to TRAIL in killing of normal and cancer cells
14. Complete cure of established murine hepatocellular carcinoma is achievable by repeated injections of retroviruses carrying the herpes simplex virus thymidine kinase gene
15. Cancer gene therapy with HSV-tk/GSV system depends on T-cell-mediated immune responses and causes apoptotic death of tumor cells in vivo
16. Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
17. A novel receptor for Apo2L/TRAIL contains a truncated death domain
18. Gene transfer into mouse lyoma cells by electroporation in high electric fields
19. High-efficiency in vivo gene transfer using intraarterial plasmid injection following in vivo electroporation
20. Lethal effect of the anti Fas antibody in mice
21. The receptor for the cytotoxic ligand TRAIL
22. An antagonist decoy receptor and a death domain-containing receptor for TRAIL
23. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
24. In vivo electrically mediated protein and gene transfer in murine melanoma
25. Experiments on an ascites hepatoma. III. The conversion of mouse hepatoma into the ascitic form
26. Control of TRAIL induced apoptosis by a family of signaling and decoy receptors
27. The TNF receptor superfamily of cellular and viral proteins: Activation, co-stimulation, and death
28. Direct gene transfer into rat liver cells by in vivo electroporation
29. Expression and anti-tumor effects of TRAIL in human cholangiocarcinoma
30. Two TNF receptors
31. TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas ligand-resistant melanoma cells and mediates CD4 T cell killing of target cells
32. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labeled annexin V
33. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
34. Identification and characterization of a new member of the TNF family that induces apoptosis
35. Electroporation-mediated IL-12 gene therapy for hepatocellular carcinoma in the mouse model