Insulin sensitizers and polycystic ovary syndrome: Can a diabetes medication treat infertility?

Fertility and Sterility

Volumn 73, Issue 6, 2000, Pages 1097-1098

  Kim, Lena H ^a   Taylor, Ann E ^b   Barbieri, Robert L ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOMIFENE CITRATE; CREATININE; FOLLITROPIN; GLUCOSE; GONADOTROPIN; INSULIN; LUTEINIZING HORMONE; METFORMIN; PIOGLITAZONE; PROGESTERONE; ROSIGLITAZONE; TROGLITAZONE;

CLINICAL FEATURE; CLINICAL TRIAL; DIABETES MELLITUS; GASTROINTESTINAL SYMPTOM; HUMAN; INFERTILITY; LACTIC ACIDOSIS; LIVER TOXICITY; OVARY POLYCYSTIC DISEASE; OVULATION; PRIORITY JOURNAL; SHORT SURVEY;

EID: 0034041859     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(00)00540-9     Document Type: Editorial

References (4)

1. Dunaif A., Segal K.R., Futterweit W., Dobrjansky A. Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome. Diabetes. 38:1989;1165-1174.
2. Nestler J.E., Jakubowicz D.J., Evans W.S., Pasquali R. Effects of metformin on spontaneous and clomiphene-induced ovulation in the polycystic ovary syndrome. New Engl J Med. 338:1998;1876-1880.
3. Pasquali R., Antenucci D., Casimirri F., Venturoli S., Paradisi R., Fabbri R., et al. Clinical and hormonal characteristics of obese amenorrheic hyperandrogenic women before and after weight loss. J Clin Endocrinol Metab. 68:1989;173-179.
4. Hasegawa I., Murakawa H., Suzuki M., Yamamoto Y., Kurabayashi T., Tanaka K. Effect of troglitazone on endocrine and ovulatory performance in women with insulin resistance-related polycystic ovary syndrome. Fertil Steril. 71:1999;323-327.