Collagen distribution and expression of matrix metalloproteinases 1 and 13 in patients with anastomotic leakage after large-bowel surgery

Langenbeck's Archives of Surgery

Volumn 386, Issue 7, 2002, Pages 502-506

  Stumpf, Michael ^a   Cao, Wei ^a   Klinge, Uwe ^a   Klosterhalfen, Bernd ^a   Kasperk, Reinhard ^a   Schumpelick, Volker ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Anastomotic leakage; Collagen type I; Collagen type III; Colorectal surgery; Matrix metalloproteinases

Indexed keywords

COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; INTERSTITIAL COLLAGENASE; STROMELYSIN;

ADULT; AGED; ANASTOMOSIS DEHISCENCE; ANASTOMOSIS LEAKAGE; ARTICLE; CLINICAL ARTICLE; COLLAGEN METABOLISM; COLLAGEN SYNTHESIS; COLON CANCER; COLON SURGERY; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK FACTOR; TISSUE LEVEL; WOUND HEALING IMPAIRMENT;

ADULT; AGED; ANASTOMOSIS, SURGICAL; COLLAGEN TYPE I; COLLAGEN TYPE II; COLON; COLONIC NEOPLASMS; COLORECTAL SURGERY; FEMALE; HUMANS; MALE; MATRIX METALLOPROTEINASES; MIDDLE AGED; PILOT PROJECTS; POSTOPERATIVE COMPLICATIONS; SURGICAL WOUND DEHISCENCE;

EID: 0036168276     PISSN: 14352443     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00423-001-0255-9     Document Type: Article

References (35)

1. Anastomotic integrity after operations for large bowel cancer: A multicentre study
2. Risk factors for anastomotic leakage after resection of rectal cancer
3. Smoking and alcohol abuse are major risk factors for anastomotic leakage in colorectal surgery
4. Risk factors for anastomotic leakage after low anterior resection with total mesorectal excision
5. Altered microperfusion at the rectal stump is predictive for rectal anastomotic leak
6. Leakage of low rectal anastomosis. An anatomic explanation?
7. Intramural pH: A quantitative measurement for predicting colorectal anastomotic healing
8. Tissue oxygen tension as a predictor of colonic anastomotic healing
9. Findings of the NCEPOD report for 1990
10. Healing of experimental colonic anastomoses. Effect of suture technique on collagen metabolism in the colonic wall
11. Changes in the connective tissue composition of the submucosal layer of colonic anastomosis
12. Fibronectin and collagen gene expression in healing experimental colonic anastomosis
13. Direct measurement of collagenase in colonic anastomosis
14. Covalent crosslinking between molecules of type I and III collagen
15. Type I and type III interactions during fibrillogenesis
16. Regulation of collagen gene expression in keloids and hypertrophic scars
17. The collagen substrate specificity of human skin fibroblast collagenases
18. Molecular cloning of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas
19. Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds
20. Cell-matrix interactions modulate interstitial collagenase expressions by human keratinocytes actively involved in wounding healing
21. Expression of the extracellular matrix proteins collagen I, collagen III and fibronectin and matrix metalloproteinase-1 and -13 in the skin of patients with inguinal hernia
22. Abnormal collagen I and III distribution in the skin of patients with incisional hernia
23. Effects of surgical experience on the results of the resection for oesophageal carcinoma
24. Reduced collagen accumulation after major surgery
25. Wound healing in the intestinal wall: A comparison between experimental ileal and colonic anastomoses
26. Wound healing in the intestinal wall. Effects of infection on experimental ileal and colonic anastomoses
27. Healing of ischemic colonic anastomosis: Fibrin sealant does not improve wound healing
28. Inta-abdominal sepsis impairs colonic reparative collagen synthesis
29. The family of matrix metalloproteinase
30. Matrix metalloproteinases
31. Role of matrix metalloproteinases in healing of colonic anastomosis
32. Expression of MMP-7 (PUMP-1) mRNA in human colorectal cancers
33. Overexpression of matrix metalloproteinase-7 mRNA in human colon carcinomas
34. Matrix metalloproteinase-1 is associated with poor prognosis in colorectal cancer
35. Chronic human wounds are associated with elevated tissue levels of MMP-9 (92 kDa gelatinase)