Importance of species selection in arrythmogenic models of Q-T interval prolongation [4]

Antimicrobial Agents and Chemotherapy

Volumn 46, Issue 3, 2002, Pages 938-939

  McDermott, Jeff S ^a   Salmen, Heinz J ^a   Cox, Bryan F ^a   Gintant, Gary A ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; DOFETILIDE; ERYTHROMYCIN; ERYTHROMYCIN LACTOBIONATE; MACROLIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARRHYTHMOGENESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTROCARDIOGRAM; HEART PAPILLARY MUSCLE; HEART REPOLARIZATION; HEART VENTRICLE ARRHYTHMIA; LETTER; MICROELECTRODE; MUSCLE ACTION POTENTIAL; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; QT INTERVAL; RAT; SPECIES DIFFERENCE;

ANIMALS; ANTI-BACTERIAL AGENTS; ARRHYTHMIA; ELECTROCARDIOGRAPHY; ERYTHROMYCIN; PAPILLARY MUSCLES; RATS; SPECIES SPECIFICITY;

EID: 0036167906     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.46.3.938-939.2002     Document Type: Letter

References (8)

1. Voltage- and time-dependent block of the delayed K+ current in cardiac myocytes by dofetilide
2. The canine Purkinje fiber: An in vitro model system for acquired long QT syndrome and drug-induced arrhythmogenesis
3. + channel diversity in the mammalian myocardium
4. Comparative pharmacodynamic analysis of Q-T interval prolongation induced by the macrolides clarithromycin, roxithromycin, and azithromycin in rats
5. Two components of cardiac delayed rectifier K+ current
6. hERG, a human inward rectifier in the voltage-gated potassium channel family
7. Comparative study of the effects of erythromycin and roxithromycin on action potential duration and potassium currents in canine Purkinje fibers and rabbit myocardium
8. + channel, erg