Comparative pharmacodynamic analysis of Q-T interval prolongation induced by the macrolides clarithromycin, roxithromycin, and azithromycin in rats

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 10, 2000, Pages 2630-2637

  Ohtani, H ^a   Taninaka, C ^a   Hanada, E ^a   Kotaki, H ^a   Sato, H ^a   Sawada, Y ^a   Iga, T ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; CLARITHROMYCIN; ERYTHROMYCIN; ROXITHROMYCIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARRHYTHMOGENESIS; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG POTENCY; DRUG SAFETY; ELECTROCARDIOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; QT INTERVAL; RAT; RISK ASSESSMENT;

ALGORITHMS; ANIMAL; ANTIBIOTICS, MACROLIDE; ARRHYTHMIA; AZITHROMYCIN; BODY TEMPERATURE; CLARITHROMYCIN; COMPARATIVE STUDY; ELECTROCARDIOGRAPHY; HEART RATE; INFUSIONS, INTRAVENOUS; MALE; MODELS, BIOLOGICAL; RATS; RATS, SPRAGUE-DAWLEY; ROXITHROMYCIN;

EID: 0033802728     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.10.2630-2637.2000     Document Type: Article

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