Impaired dental cytodifferentiation in glial cell-line derived growth factor (GDNF) deficient mice

Annals of Anatomy

Volumn 184, Issue 1, 2002, Pages 85-92

  De Vicente, J C ^a   Cabo, R ^b   Ciriaco, E ^c   Laura R ^c   Naves, F J ^d   Silos Santiago, I ^e   Vega, J A ^d  

^a Escuela de Estomatología   (Spain)

^b UNIVERSITY OF OVIEDO   (Spain)

^c UNIVERSITY OF VALLADOLID   (Spain)

^d UNIVERSITY OF MESSINA   (Italy)

^e MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

GDNF deficient mice; Glial cell line derived neurotrophic factor (GDNF); Tooth development; Tooth innervation; Trigeminal ganglion

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR; UNCLASSIFIED DRUG;

AMELOBLAST; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CELL DIFFERENTIATION; CELL MATURATION; CELL SURVIVAL; CELL TYPE; CELL ULTRASTRUCTURE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DENTIN; ENAMEL; HETEROZYGOSITY; INTESTINE INNERVATION; KNOCKOUT MOUSE; MOLAR TOOTH; MORPHOGENESIS; MOUSE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NEWBORN; NONHUMAN; ODONTOBLAST; ORGANOGENESIS; PERIPHERAL NERVOUS SYSTEM; PROTEIN EXPRESSION; SENSORY NERVE CELL; TOOTH DEVELOPMENT; TRIGEMINUS GANGLION; WILD TYPE;

ANIMALIA;

EID: 0036166315     PISSN: 09409602     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0940-9602(02)80041-3     Document Type: Article

References (37)

1. The GDNF family ligands and receptors - Implications for neural development
2. GFRα1 is an essential receptor component for GDNF in the developing nervous system and kidney
3. Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth
4. Lack of neurotrophin 3 causes losses of both classes of spiral ganglion neurons in the cochlea in a region-specific fashion
5. Expression of neurturin, GDNF, and GDNF family-receptor mRNA in the developing and mature mouse
6. Morphological alterations in the peripheral and central nervous system of mice lacking glial cell line-derived neurotrophic factor (GDNF): Immunohistochemical studies
7. GDNF mRNA in Schwann cells and DRG satellite cells after chronic sciatic nerve injury
8. Bone morphogenetic protein-7 (osteogenic protein-1, OP-1) and tooth development
9. Embryonic expression of glial cell line-derived neurotrophic factor (GDNF) suggests multiple developmental roles in neural differentiation and epithelial-mesenchymal interactions
10. Schwann cells and their precursors emerge as major regulators of nerve development
11. Tooth pulp tissue promotes neurite outgrowth from rat trigeminal ganglia in vitro
12. An experimental study of timing and topography of early tooth development in the mouse embryo with an analysis of the role of innervation
13. Neurotrophin mRNA expression in the developing tooth suggests multiple roles in innervation and organogenesis
14. Expression of GDNF and its receptors in developing tooth is developmentally regulated and suggests multiple roles in innervation and organogenesis
15. Neurturin mRNA expression suggests roles in trigeminal innervation of the first branchial arch and in tooth formation
16. Neuronal cells and neurotrophins in odontogenesis
17. Renal and neuronal abnormalities in mice lacking GDNF
18. Expression and regulation of GFRα3, a glial cell line-derived neurotrophic factor family receptor
19. Cellular expression of GDNF mRNA suggest multiple functions inside and outside the nervous system
20. Cellular expression of neurotrophin mRNAs during tooth development
21. NGF, BDNF, NT3, NT4 and GDNF in tooth development
22. Defects in enteric innervation and kidney development in mice lacking GDNF
23. Glial cell line-derived neurotrophic factor-like immunoreactivity in human trigeminal ganglion and nucleus
24. The GDNF protein family: Genes ablation studies reveal what they really do and how
25. Basic fibroblast growth factor (FGF-2) in mouse tooth morphogenesis
26. Other neurotrophic factors: Glial cell line-derived neurotrophic factor
27. Renal agenesis and the absence of enteric neurons in mice lacking GDNF
28. Defects in kidney and enteric nervous system of mice lacking tyrosine kinase receptor
29. Hepatocyte growth factor is involved in the morphogenesis of tooth germ in murine molars
30. Regulation of organogenesis. Common molecular mechanisms regulating the development of teeth and other organs
31. Epithelial-mesenchymal signalling during tooth development
32. Tooth morphogenesis and cell differentiation
33. Signalling networks regulating dental development
34. Expression of TGF-beta superfamily receptors in dental pulp
35. Neurturin and glial cell line-derived neurotrophic factor-β (GDNFR-β), novel proteins related to GDNF and GDNFR-α with specific cellular roles in the developing and adult nervous system and in peripheral organs
36. GFRα-3, a protein related to GFRα-1, is expressed in developing peripheral neurons and ensheathing cells
37. GDNF, RTE and GFRα-1-3 mRNA expression in the developing human spinal cord and ganglia