Effects of isopropyl unoprostone and latanoprost on melanogenesis in mouse epidermal melanocytes

Journal of Glaucoma

Volumn 11, Issue 1, 2002, Pages 57-64

  Kashiwagi, Kenji ^a   Tsukamoto, Katsuhiko ^a   Suzuki, Michihiro ^b   Tsukahara, Shigeo ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b The Corporation for Production and Research of Laboratory Primates   (Japan)

Author keywords

Isopropyl unoprostone; Latanoprost; Melano genesis; Melanocyte; Prostaglandin F2 ; Tyrosinase

Indexed keywords

ANTIGLAUCOMA AGENT; LATANOPROST; LEVODOPA; MELAN A; MELANIN; MONOPHENOL MONOOXYGENASE; PROSTAGLANDIN F2 ALPHA; TYROSINE; UNOPROSTONE ISOPROPYL ESTER;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; DRUG STRUCTURE; ENZYME ACTIVITY; MELANOCYTE; MELANOGENESIS; MOUSE; NONHUMAN; PIGMENTATION; PRIORITY JOURNAL;

EID: 0036164797     PISSN: 10570829     EISSN: None     Source Type: Journal    
DOI: 10.1097/00061198-200202000-00011     Document Type: Article

References (51)

1. The potential of prostaglandin derivatives in glaucoma therapy
2. Clinical evaluation of UF-201 ophthalmic solution in glaucoma patients refractory to maximum tolerable therapy
3. Initial clinical studies with prostaglandins and their analogues
4. Prostaglandins: A new approach to glaucoma management with a new, intriguing side effect
5. Unoprostone (isopropyl unoprostone)
6. Prostaglandin-induced iridial pigmentation in primates
7. Effects on intraocular pressure and side effects of 0.005% latanoprost applied once daily, evening or morning. A comparison with timolol. Report prepared for the Scandinavian Latanoprost Study Group
8. Comparison of latanoprost and timolol in patients with ocular hypertension and glaucoma: A six-month masked, multicenter trial in the United States. Report prepared for the United States Latanoprost Study Group
9. A six-month, randomized, double-masked study comparing latanoprost with timolol in open-angle glaucoma and ocular hypertension. Report prepared for the Latanoprost Study Group
10. The incidence and time-course of latanoprost-induced iridial pigmentation as a function of eye color
11. Increased eyelid pigmentation associated with use of latanoprost
12. Effects of latanoprost on tyrosinase activity and mitotic index of cultured melanoma lines
13. The color of the human eye: A review of morphologic correlates and of some conditions that affect iridial pigmentation
14. Effect of prostaglandins A(2), E(1), F(2 alpha) and latanoprost on cultured human iridal melanocytes
15. Latanoprost stimulates eumelanogenesis in iridial melanocytes of cynomolgus monkeys
16. Prostaglandin-induced iris color darkening. An experimental model
17. Latanoprost-induced increase of tyrosinase transcription in iridial melanocytes
18. Iris-color change developed after topical isopropyl unoprostone treatment
19. Iris pigmentation in two cases after topical instillation of isopropyl unoprostone
20. Computer-assisted iris color analysis in a 52-week ocular chronic toxicity study on rescula eye-drops in cynomolgus monkeys
21. Melanocyte-stimulating properties of arachidonic acid metabolites: Possible role in postinflammatory pigmentation
22. Prostaglandin E2 and D2 but not MSH stimulate the proliferation of pigment cells in the pinnal epidermis of the DBA/2 mouse
23. Tyrosinase and related proteins in mammalian pigmentation
24. Alpha-methyl-p-tyrosine inhibits latanoprost-induced melanogenesis in vitro
25. Effects of isopropyl unoprostone on melanogenesis in mouse epidermal melanocytes
26. A line of non-tumorigenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumor promoter for growth
27. Pigment production in murine melanoma cells is regulated by tyrosinase, tyrosinase-related protein I (TRPI), DOPAchrome tautomerase (TRP2), and a melanogenic inhibitor
28. Multiple dosing of prostaglandin F2 alpha or epinephrine on cynomolgus monkey eyes. III
29. Metabolites of isopropyl unoprostone as potential ophthalmic solutions to reduce intraocular pressure in pigmented rabbits
30. Mammalian tyrosinase. A comparison of tyrosine hydroxylation and melanin formation
31. Expression of melanocyte stimulating hormone receptors correlates with mammalian pigmentation, and can be modulated by interferons
32. Melanin biosynthesis patterns after hormonal stimulation
33. A sensitive new assay for the oxidation of 3,4-dihydroxy L-phenylalanine by tyrosinase
34. Increased pigmentation of iridial melanocytes in primates induced by a prostaglandin analogue
35. Biochemical control of melanogenesis and melanosomal organization
36. Signaling pathways mediating melano-genesis
37. A review of recent advances on the regulation of pigmentation in the human epidermis
38. Metabolization of unoprostone isopropyl (UF-021) in isolated pig cornea
39. Ocular penetration of UF-021, a new prostaglandin related compound, in the rabbit eye
40. The pharmacokinetics of a new antiglaucoma drug, latanoprost, in the rabbit
41. Pharmacokinetics of latanoprost in the cynomolgus monkey 3rd communication: Tissue distribution after topical administration on the eye studied by whole body autoradiography
42. Pharmacokinetics of latanoprost in the cynomolgus monkey 1st communication: Single intraveneous, oral or topical administration on the eye
43. Multiple dosing of prostaglandin F2 alpha or epinephrine on cynomolgus monkey eyes. 11. Slit-lamp biomicroscopy, aqueous humor analysis, and fluorescein angiography
44. Regulation of growth and melanogenesis of uveal melanocytes
45. Pharmacological characterization of prostaglandin-related ocular hypotensive agents
46. Comparison between isopropyl unoprostone and latanoprost by prostaglandin E2 induction, affinity to prostaglandin transporter, and intra-ocular metabolism
47. Ocular hypotensive mechanism of topical isopropyl unoprostone, a novel prostaglandin metabolite-related drug, in rabbits
48. Prostaglandin F2 alpha and its analogs induce release of endogenous prostaglandins in iris and ciliary muscles isolated from cat and other mammalian species
49. Iridial pigmentation and hypertrichosis of eyelids caused by latanoprost instillation
50. Hypertrichosis and increased pigmentation of eyelashes and adjacent hair in the region of the ipsilateral eyelids of patients treated with unilateral topical latanoprost
51. Melan-A, a new melanocytic differentiation marker