Leishmania (L.) amazonensis-induced inhibition of nitric oxide synthesis in host macrophages

Microbes and Infection

Volumn 4, Issue 1, 2002, Pages 23-29

  Perrella Balestieri, Filomena M ^a   Pires Queiroz, Allan R ^b   Scavone, Cristoforo ^c   Assis Costa, Vlaudia M ^c   Barral Netto, Manoel ^b   Abrahamsohn, Ises de Almeida ^c  

^a FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

^b FEDERAL UNIVERSITY OF BAHIA   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

IFN ; INOS activity; INOS mRNA; Leishmania (L.) amazonensis; Macrophage; Nitric oxide

Indexed keywords

ARGININE; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10 ANTIBODY; INTERLEUKIN 4 ANTIBODY; LIPOPOLYSACCHARIDE; MESSENGER RNA; NEUTRALIZING ANTIBODY; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TETRAHYDROBIOPTERIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; LEISHMANIA; LEISHMANIASIS; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMASTIGOTE;

LEISHMANIA AMAZONENSIS;

EID: 0036161776     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1286-4579(01)01505-2     Document Type: Article

References (37)

1. Immunology of leishmaniasis
2. Cell biology of Leishmania
3. Modulation of nitric oxide synthase activity in macrophages
4. The host response to Leishmania major
5. Inhibition of constitutive and inducible nitric oxide synthase: Potencial selective inhibition
6. Structure-function aspects in the nitric oxide synthases
7. Effect of in vivo inhibition of nitric oxide production in murine leishmaniasis
8. G-monomethyl-arginine in vitro and in vivo
9. Altered immune responses in mice lacking inducible nitric oxide synthase
10. Transforming growth factor-β in leishmanial infection: A parasite escape mechanism
11. Deficient expression of co-stimulatory molecules on Leishmania-infected macrophages
12. Phagocytosis of Leishmania mexicana amastigotes by macrophages leads to a sustained suppression of IL-12 production
13. The IL-4 rapidly produced in BALB/c mice after infection with Leishmania major down-regulates IL-12 receptor β2-chain expression on CD4+ T cells resulting in a state of unresponsiveness to IL-12
14. Extracellular Signal-Related Kinase (ERK) and p38 Mitogen-Activated Protein (MAP) kinases differentially regulate the Lipopolysaccharide-mediated induction of inducible Nitric Oxide Synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP Kinase
15. Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice
16. Transforming growth factor β as a virulence mechanism for Leishmania braziliensis
17. Glycoinositolphospholipids of Leishmania major inhibit nitric oxide synthesis and reduce leishmanicidal activity in murine macrophages
18. Regulation of the expression of nitric oxide synthase and leishmanicidal activity by glycoconjugates of Leishmania lipophosphoglycan in murine macrophages
19. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production
20. Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: An FAD- and FMN-containing flavoprotein
21. Constructing polycompetitor cDNAs for quantitative PCR
22. 1
23. Cytokine and nitric oxide regulation of the immunosuppression in Trypanosoma cruzi infection
24. Trypanosoma cruzi affects nitric oxide production by murine peritoneal macrophages
25. Nitric oxide and mycobacterial growth inhibition by murine alveolar macrophages: The sequence of rIFN-γ stimulation and Mycobacterium bovis BCG infection determines macrophage activation
26. Cryptococcus neoformans inhibits nitric oxide production by murine peritoneal macrophages stimulated with interferon-γ and lipopolysaccharide
27. Isolation and characterization of the Leishmania donovani kinetoplastid membrane protein-11, a major immunoreactive membrane glycoprotein
28. Inducible nitric-oxide-synthase mRNA is transiently expressed and destroyed by a cycloheximide-sensitive process
29. Role of endogenous Interferon-β in lipopolysaccharide-triggered activation of the inducible nitric-oxide synthase gene in a mouse macrophage cell line, J774
30. Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor β
31. Mechanism of suppression of nitric oxide synthase expression by interleukin-4 in primary mouse macrophages
32. FAD and GSH participate in macrophage synthesis of nitric oxide
33. Macrophage nitric oxide synthase subunits. Purification, characterization, and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme
34. Catalase inhibits nitric oxide synthesis and the killing of intracellular Leishmania major in murine macrophages
35. L-arginine transport is increased in macrophages generating nitric oxide
36. Characterization of the active site of arginase from Leishmania (L.) amazonensis based on the enzyme structure defined for Rattus novergicus
37. 2+ ionophore. Dependence on L-arginine-derived nitrogen oxidation products