The SAG5 locus of Toxoplasma gondii encodes three novel proteins belonging to the SAG1 family of surface antigens

International Journal for Parasitology

Volumn 32, Issue 2, 2002, Pages 121-131

  Spano, Furio ^a   Ricci, Irene ^b   Di Cristina, Manlio ^c   Possenti, Alessia ^a   Tinti, Michele ^a   Dendouga, Najoua ^d   Tomavo, Stanislas ^d   Crisanti, Andrea ^c  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d UNIV LILLE   (France)

Author keywords

Expression analysis; Molecular cloning; Multigene locus; SAG1 family; Toxoplasma gondii; Transient transfection

Indexed keywords

AMINO ACID; GLYCOSYLPHOSPHATIDYLINOSITOL; MEMBRANE ANTIGEN; PHOSPHOLIPASE C; POLYPEPTIDE; PROTEIN SAG1; PROTEIN SAG5A; PROTEIN SAG5B; PROTEIN SAG5C; UNCLASSIFIED DRUG;

PARASITOLOGY;

AMINO TERMINAL SEQUENCE; ANTIGEN EXPRESSION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENE CLUSTER; GENE LOCUS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; INTRON; NONHUMAN; PARASITE VIRULENCE; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; TOXOPLASMA GONDII;

TOXOPLASMA GONDII;

EID: 0036153526     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(01)00349-6     Document Type: Article

References (46)

1. Tandemly repeated genes encode nucleoside triphosphate hydrolase isoforms secreted into the parasitophorous vacuole of Toxoplasma gondii
2. The lytic cycle of Toxoplasma gondii
3. Bradyzoite-specific gene expression in Toxoplasma gondii requires minimal genomic elements
4. Isolation of integral membrane proteins by phase partitioning with Triton X-1114
5. Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii
6. Similarities between the primary structures of two distinct major surface proteins of Toxoplasma gondii
7. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
8. Surface antigens of Toxoplasma gondii
9. Toxoplasma gondii: Redistribution of monoclonal antibodies on tachyzoites during host cell invasion
10. Targeted disruption of the glycosylphosphatidylinositol-anchored surface antigen SAG3 gene in Toxoplasma gondii decreases host cell adhesion and drastically reduces virulence in mice
11. Toxoplasma gondii: The role of a 30-kDa surface protein in host cell invasion
12. Detection and characterization of membrane antigens of Toxoplasma gondii
13. Identification and characterization of SRS1, a Toxoplasma gondii surface antigen upstream of and related to SAG1
14. Characterization of a cDNA-clone encoding Nc-p43, a major Neospora caninum tachyzoite surface protein
15. Purification of recombinant proteins with metal chelate adsorbent
16. Toxoplasma gondii comprises three clonal lineages: Correlation of parasite genotype with human disease
17. The p29 and p35 immunodominant antigens of Neospora caninum tachyzoites are homologous to the family of surface antigens of Toxoplasma gondii
18. Toxoplasmosis in non-AIDS immunocompromised host
19. The surface antigen SAG3 mediates the attachment of Toxoplasma gondii to cell-surface proteoglycans
20. Speculation on possible life cycles for the clonal lineages in the genus Toxoplasma
21. Isolation and characterization of a monoclonal anti-P30 antibody resistant mutant of Toxoplasma gondii
22. Isolation and characterization of a monoclonal antibody-resistant antigenic mutant of Toxoplasma gondii
23. Isolation of developmentally regulated genes from Toxoplasma gondii by a gene trap with the positive and negative selectable marker hypoxanthine-xanthine-guanine phosphoribosyltransferase
24. Biosynthesis of glycosylphosphatidylinositol (GPI)-anchored membrane proteins in intact cells: Specific amino acid requirements adjacent to the site of cleavage and GPI attachment
25. Toxoplasma gondii: Identification of a developmentally regulated family of genes related to SAG2
26. Surface antigens of Toxoplasma gondii: Variations on a theme
27. Toxoplasmic encephalitis in AIDS
28. The surface of Toxoplasma tachyzoites is dominated by a family of glycosylphosphatidylinositol-anchored antigens related to SAG1
29. Antibodies to Toxoplasma gondii major surface protein (SAG-1, P30) inhibit infection of host cells and are produced in murine intestine after peroral infection
30. Molecular cloning, expression analysis and iron metal cofactor characterisation of a superoxide dismutase from Toxoplasma gondii
31. Cloning, expression, and cDNA sequence of surface antigen P22 from Toxoplasma gondii
32. Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii
33. Consensus sequence of translational initiation sites from Toxoplasma gondii genes
34. Virulent strains of Toxoplasma gondii comprise a single clonal lineage
35. Transient transfection and expression in the obligate intracellular parasite Toxoplasma gondii
36. A selector of transcription initiation in the protozoan parasite Toxoplasma gondii
37. The major 36 kDa Neospora caninum tachyzoite surface protein is closely related to the major Toxoplasma gondii surface antigen
38. Molecular cloning and expression analysis of a Cryptosporidium parvum gene encoding a new member of the thrombospondin family
39. Toxoplasma gondii: From animals to humans
40. The major surface antigens of Toxoplasma gondii: Structures and functions
41. Evidence for glycosylphosphatidylinositol anchoring of Toxoplasma gondii major surface antigens
42. A new method for predicting signal sequences from 699 vertebrate messenger RNAs
43. The development and biology of bradyzoites of Toxoplasma gondii
44. Toxoplasmosis in pregnancy
45. Toxoplasma gondii expresses two distinct lactate dehydrogenase homologous genes during its life cycle in intermediate hosts