메뉴 건너뛰기




Volumn 14, Issue 5, 1999, Pages 411-420

A similarity model for the human angiogenic factor, thymidine phosphorylase/platelet derived-endothelial cell growth factor

Author keywords

Angiogenesis; Docking; Inhibitors; Oxycarbenium ion; PD ECGF; Similarity modelling; Thymidine phosphorylase

Indexed keywords

5 CHLORO 6 [1 (2 IMINOPYRROLIDINYL)METHYL]URACIL; ANGIOGENIC FACTOR; PLATELET DERIVED ENDOTHELIAL CELL GROWTH FACTOR; THYMIDINE; THYMIDINE PHOSPHORYLASE; THYMINE; UNCLASSIFIED DRUG; URACIL DERIVATIVE;

EID: 0033504249     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (16)

References (39)
  • 4
    • 0028050261 scopus 로고
    • OWL - A non-redundant, composite protein sequence database
    • Bleasby A.J., Akrigg D., Attwood T.K. (1994) OWL - a non-redundant, composite protein sequence database. Nucleic Acids Research, 22, 3574.
    • (1994) Nucleic Acids Research , vol.22 , pp. 3574
    • Bleasby, A.J.1    Akrigg, D.2    Attwood, T.K.3
  • 5
    • 0020441466 scopus 로고
    • Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 Å resolution
    • Bolin J.T., Filman D.J., Matthews D.A., Hamlin R.C., Kraut J. (1982) Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 Å resolution. The Journal of Biological Chemistry, 257, 13650.
    • (1982) The Journal of Biological Chemistry , vol.257 , pp. 13650
    • Bolin, J.T.1    Filman, D.J.2    Matthews, D.A.3    Hamlin, R.C.4    Kraut, J.5
  • 7
    • 0032529047 scopus 로고    scopus 로고
    • Thymidine phosphorylase, 2-deoxy-D-ribose and angiogenesis
    • Brown N.S., Bicknell R. (1998) Thymidine phosphorylase, 2-deoxy-D-ribose and angiogenesis. Biochemistry Journal, 334, 1.
    • (1998) Biochemistry Journal , vol.334 , pp. 1
    • Brown, N.S.1    Bicknell, R.2
  • 8
    • 0000053675 scopus 로고
    • Intramolecular C-HO interactions in the main nucleosides from crystallographic data. Refinement of the crystal structure of thymidine
    • Chekhlov A.N. (1995) Intramolecular C-HO interactions in the main nucleosides from crystallographic data. Refinement of the crystal structure of thymidine. Zhurnal Strukturnoi Khimii, 36, 178.
    • (1995) Zhurnal Strukturnoi Khimii , vol.36 , pp. 178
    • Chekhlov, A.N.1
  • 9
    • 0024297354 scopus 로고
    • Multiple sequence alignment with hierarchical clustering
    • Corpet F. (1994) Multiple sequence alignment with hierarchical clustering. Nucleic Acids Research, 16, 10881.
    • (1994) Nucleic Acids Research , vol.16 , pp. 10881
    • Corpet, F.1
  • 11
    • 0019404119 scopus 로고
    • Catabolism of thymidine in human blood platelets. Purification and properties of thymidine phosphorylase
    • Desgranges C., Razaka G., Rabaud M., Bricaud H. (1981) Catabolism of thymidine in human blood platelets. Purification and properties of thymidine phosphorylase. Biochimica et Biophysica Acta, 654, 211.
    • (1981) Biochimica et Biophysica Acta , vol.654 , pp. 211
    • Desgranges, C.1    Razaka, G.2    Rabaud, M.3    Bricaud, H.4
  • 14
    • 0016771378 scopus 로고
    • The refined crystal structure of bovine β-trypsin at 1.8 Å resolution
    • Fehlhammer H., Bode W. (1975) The refined crystal structure of bovine β-trypsin at 1.8 Å resolution. Journal of Molecular Biology, 98, 683.
    • (1975) Journal of Molecular Biology , vol.98 , pp. 683
    • Fehlhammer, H.1    Bode, W.2
  • 15
    • 0027530691 scopus 로고
    • Thymidine phosphorylase activity of platelet-derived endothelial cell growth factor is responsible for endothelial cell mitogenicity
    • Finnis C., Dodsworth N, Pollitt C.E., Carr G., Sleep D. (1993) Thymidine phosphorylase activity of platelet-derived endothelial cell growth factor is responsible for endothelial cell mitogenicity. European Journal of Biochemistry, 212, 201.
    • (1993) European Journal of Biochemistry , vol.212 , pp. 201
    • Finnis, C.1    Dodsworth, N.2    Pollitt, C.E.3    Carr, G.4    Sleep, D.5
  • 17
    • 0030767340 scopus 로고    scopus 로고
    • Platelet-derived endothelial cell growth factor/thymidine phosphorylase in tumour growth and response to therapy
    • Griffiths L., Stratford I.J. (1997) Platelet-derived endothelial cell growth factor/thymidine phosphorylase in tumour growth and response to therapy. British Journal of Cancer, 76, 689.
    • (1997) British Journal of Cancer , vol.76 , pp. 689
    • Griffiths, L.1    Stratford, I.J.2
  • 18
    • 0001010885 scopus 로고
    • Representation of van der Waals (vdW) interactions in molecular mechanics force fields: Potential form, combination rules, and vdW parameters
    • Halgren T.A. (1992) Representation of van der Waals (vdW) interactions in molecular mechanics force fields: potential form, combination rules, and vdW parameters. Journal of the American Chemical Society, 114, 7827.
    • (1992) Journal of the American Chemical Society , vol.114 , pp. 7827
    • Halgren, T.A.1
  • 21
    • 0032520168 scopus 로고    scopus 로고
    • Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts
    • Ishikawa T., Sekiguchi F., Fukase Y., Sawada N., Ishitsuka H. (1998) Positive correlation between the efficacy of Capecitabine and Doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts. Cancer Research, 58, 685.
    • (1998) Cancer Research , vol.58 , pp. 685
    • Ishikawa, T.1    Sekiguchi, F.2    Fukase, Y.3    Sawada, N.4    Ishitsuka, H.5
  • 22
    • 0019452460 scopus 로고
    • Enzymatic function of 5-fluorouracil from 1-(tetrahydro-2-furanyl)-5-fluorouracil (tegafur) in human tumor tissues
    • Kono A., Hara Y., Matsushima Y. (1981) Enzymatic function of 5-fluorouracil from 1-(tetrahydro-2-furanyl)-5-fluorouracil (Tegafur) in human tumor tissues. Chemical and Pharmaceutical Bulletin, 29, 1486.
    • (1981) Chemical and Pharmaceutical Bulletin , vol.29 , pp. 1486
    • Kono, A.1    Hara, Y.2    Matsushima, Y.3
  • 25
    • 0014197030 scopus 로고
    • Inhibition of thymidine phosphorylase by 6-aminothymine and derivatives of 6-aminouracil
    • Langen P., Etzold G., Bärwolff D., Preussel B. (1967) Inhibition of thymidine phosphorylase by 6-aminothymine and derivatives of 6-aminouracil. Biochemical Pharmacology, 16, 1833.
    • (1967) Biochemical Pharmacology , vol.16 , pp. 1833
    • Langen, P.1    Etzold, G.2    Bärwolff, D.3    Preussel, B.4
  • 27
    • 0028018118 scopus 로고
    • Pyrimidine nucleotide metabolism in human colon carcinomas: Comparison of normal tissues, primary tumors and xenografts
    • Luccioni C., Beaumartin J., Bardot V., Lefrançois D. (1994) Pyrimidine nucleotide metabolism in human colon carcinomas: comparison of normal tissues, primary tumors and xenografts. International Journal of Cancer, 58, 517.
    • (1994) International Journal of Cancer , vol.58 , pp. 517
    • Luccioni, C.1    Beaumartin, J.2    Bardot, V.3    Lefrançois, D.4
  • 28
    • 0020655660 scopus 로고
    • Structure-activity relationship of ligands of the pyrimidine nucleoside phosphorylases
    • Niedzwicki J.G., El Kouni M.H., Chu S.H., Cha S. (1983) Structure-activity relationship of ligands of the pyrimidine nucleoside phosphorylases. Biochemical Pharmacology, 32, 399.
    • (1983) Biochemical Pharmacology , vol.32 , pp. 399
    • Niedzwicki, J.G.1    El Kouni, M.H.2    Chu, S.H.3    Cha, S.4
  • 29
    • 0032516763 scopus 로고    scopus 로고
    • Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase
    • Pugmire M.J., Cook W.J., Jasanoff A., Walter M.R., Ealick S.E. (1998) Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase. Journal of Molecular Biology, 281, 285.
    • (1998) Journal of Molecular Biology , vol.281 , pp. 285
    • Pugmire, M.J.1    Cook, W.J.2    Jasanoff, A.3    Walter, M.R.4    Ealick, S.E.5
  • 30
    • 0032533446 scopus 로고    scopus 로고
    • The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation
    • Pugmire M.J., Ealick S.E. (1998) The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation. Structure, 6, 1467.
    • (1998) Structure , vol.6 , pp. 1467
    • Pugmire, M.J.1    Ealick, S.E.2
  • 31
    • 0027291015 scopus 로고
    • Prediction of protein structure at better than 70% accuracy
    • Rost B., Sander C. (1993) Prediction of protein structure at better than 70% accuracy. Journal of Molecular Biology, 232, 584.
    • (1993) Journal of Molecular Biology , vol.232 , pp. 584
    • Rost, B.1    Sander, C.2
  • 32
    • 0028300741 scopus 로고
    • Combining evolutionary information and neural networks to predict protein secondary structure
    • Rost B., Sander C. (1994) Combining evolutionary information and neural networks to predict protein secondary structure. Proteins, 19, 55.
    • (1994) Proteins , vol.19 , pp. 55
    • Rost, B.1    Sander, C.2
  • 35
    • 0006467121 scopus 로고    scopus 로고
    • Invention of a novel antitumor agent, TAS-102. Antitumor activities of 5-trifluorothymidine combined with a new inhibitor of thymidine phosphorylase
    • Suzuki N., Fukushima M., Asao T., Yamada Y., Akiyama S. (1997) Invention of a novel antitumor agent, TAS-102. Antitumor activities of 5-trifluorothymidine combined with a new inhibitor of thymidine phosphorylase. Proceedings of the American Association for Cancer Research, 38, 101.
    • (1997) Proceedings of the American Association for Cancer Research , vol.38 , pp. 101
    • Suzuki, N.1    Fukushima, M.2    Asao, T.3    Yamada, Y.4    Akiyama, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.