Multiple nodal-related genes act coordinately in Xenopus embryogenesis

Developmental Biology

Volumn 241, Issue 1, 2002, Pages 94-105

  Onuma, Yasuko ^a   Takahashi, Shuji ^a,b   Yokota, Chika ^a,b   Asashima, Makoto ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Cleavage mutant; Nodal; Superfamily; TGF ; Xenopus; Xnr6; XnrS

Indexed keywords

ACTIVIN; PROTEIN BVG1; PROTEIN DERRIERE; PROTEIN NODAL; PROTEIN SIAMOIS; PROTEIN XNR1; PROTEIN XNR2; PROTEIN XNR4; PROTEIN XNR5; PROTEIN XNR6; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIMERIZATION; EMBRYO; EMBRYO DEVELOPMENT; ENDODERM; GASTRULATION; GENE OVEREXPRESSION; IN SITU HYBRIDIZATION; MESODERM; NONHUMAN; OOCYTE CLEAVAGE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; XENOPUS;

XENOPUS;

EID: 0036147869     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2001.0493     Document Type: Article

References (56)

1. Endodermal Nodal-related signals and mesoderm induction in Xenopus
2. Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer
3. Activation of Siamois by the Wnt pathway
4. The homeobox gene Siamois is a target of the Wnt dorsalisation pathway and triggers organiser activity in the absence of mesoderm
5. A post-mid-blastula transition requirement for TGFβ signaling in early endodermal specification
6. Molecular nature of Spemann's organizer: The role of the Xenopus homeobox gene goosecoid
7. Mode of action of VegT in mesoderm and endoderm formation
8. A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse
9. Requirement for anti-dorsalizing morphogenetic protein in organizer patterning
10. Endogenous patterns of TGFβ superfamily signaling during early Xenopus development
11. Zebrafish organizer development and germ-layer formation require nodal-related signals
12. Direct neural induction and selective inhibition of mesoderm and epidermis inducers by Xnr3
13. Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction
14. Patterning the Xenopus blastula
15. Beta-catenin signaling activity dissected in the early Xenopus embryo: A novel antisense approach
16. Mixer, a homeobox gene required for endoderm development
17. Xsoxl7α and -β mediate endoderm formation in Xenopus
18. Regulation of the early expression of the Xenopus nodal-related 1 gene, Xnrl
19. Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation
20. Xnr4: A Xenopus nodal-related gene expressed in the Spemann organizer
21. Mutant Vgl ligands disrupt endoderm and mesoderm formation in Xenopus embryos
22. Mesoderm induction: A postmodern view
23. Vertebrate mesendoderm induction and patterning
24. Mesoderm induction in Xenopus is a zygotic event regulated by maternal VegT via TGFβ growth factors
25. Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDNAs
26. Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis
27. Dominant negative mutants of transforming growth factor-β1 inhibit the secretion of different transforming growth factor-β isoforms
28. A Xenopus nodal-related gene that acts in synergy with noggin to induce complete secondary axis and notochord formation
29. Ventral mesoderm induction and patterning by bone morphogenetic protein heterodimers in Xenopus embryos
30. Molecular cloning of a novel Xenopus spalt gene (Xsal-3)
31. Activin/nodal responsiveness and asymmetric expression of a Xenopus nodal-related gene converge on a FAST-regulated module in intron 1
32. Xenopus nodal-related signaling is essential for mesendodermal patterning during early embryogenesis
33. Expression and post-transcriptional regulation of ornithine decarboxylase during early Xenopus development
34. The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals
35. Functional differences among Xenopus nodal-related genes in left-right axis determination
36. A sticky problem: The Xenopus cement gland as a paradigm for anteroposterior patterning
37. Progressive determination during formation of the anteroposterior axis in Xenopus laevis
38. Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction
39. A nodal-related gene defines a physical and functional domain within the Spemann organizer
40. Injected Wnt RNA induces a complete body axis in Xenopus embryos
41. Derriere: A TGF-β family member required for posterior development in Xenopus
42. Cloning and expression pattern of Xenopus prx-1 (Xprx-1) during embryonic development
43. Two novel nodal-related genes initiate early inductive events in Xenopus Nieuwkoop center
44. Expression cloning of Xantivin, a Xenopus lefty/antivin-related gene, involved in the regulation of activin signaling during mesoderm induction
45. Processed Vg1 protein is an axial mesoderm inducer in Xenopus
46. Nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation
47. Induction of the Xenopus organizer: Expression and regulation of Xnot, a novel FGF and activin-regulated homeo box gene
48. Inhibition of morphogenetic movement during Xenopus gastrulation by injected sulfatase: Implications for anteroposterior and dorsoventral axis formation
49. A maternal mRNA localized to the vegetal hemisphere in Xenopus eggs codes for a growth factor related to TGF-β
50. Disruption of mesoderm and axis formation in fish by ectopic expression of activin variants: The role of maternal activin
51. Maternal VegT is the initiator of a molecular network specifying endoderm in Xenopus laevis
52. A two-step model for the fate determination of presumptive endodermal blastomeres in Xenopus embryos
53. The role of maternal VegT in establishing the primary germ layers in Xenopus embryos
54. Xenopus VegT RNA is localized to the vegetal cortex during oogenesis and encodes a novel T-box transcription factor involved in mesodermal patterning
55. Nodal is a novel TGF-β-1ike gene expressed in the mouse node during gastrulation