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Volumn 95, Issue 1-2, 2002, Pages 65-74

Sex-specific differences in levels of morphine, morphine-3-glucuronide, and morphine antinociception in rats

Author keywords

Morphine; Morphine 3 glucuronide; Pain; Rats; Sex

Indexed keywords

MORPHINE; MORPHINE 3 GLUCURONIDE;

EID: 0036145364     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(01)00376-1     Document Type: Article
Times cited : (45)

References (78)
  • 25
    • 0026006832 scopus 로고
    • A simple, rapid method for simultaneous determination of morphine and its principal metabolites in plasma using high-performance liquid chromatography and fluorometric detection
    • (1991) Ther Drug Monit , vol.13 , pp. 226-232
    • Glare, P.A.1    Walsh, T.D.2    Pippenger, C.E.3
  • 27
    • 0026501373 scopus 로고
    • Morphine-3-glucuronide may functionally antagonize morphine-6-glucuronide induced antinociception and ventilatory depression in the rat
    • (1992) Pain , vol.48 , pp. 249-255
    • Gong, Q.1    Hedner, J.2    Bjorkman, R.3    Hedner, T.4
  • 29
    • 0028158255 scopus 로고
    • Concentrations of morphine, morphine-6-glucuronide and morphine-3-glucuronide in serum and cerebrospinal fluid following morphine administration to patients with morphine-resistant pain
    • (1994) Pain , vol.56 , pp. 145-149
    • Goucke, C.R.1    Hackett, L.P.2    Ilett, K.F.3
  • 30
    • 0027460865 scopus 로고
    • Morphine pharmacokinetics and metabolism in humans. Enterohepatic cycling and relative contribution of metabolites to active opioid concentrations
    • (1993) Clin Pharmacokinet , vol.24 , pp. 344-354
    • Hasselstrom, J.1    Sawe, J.2
  • 31
    • 0028567201 scopus 로고
    • Repetitive exposure to the hot-plate test produces stress induced analgesia and alters β-endorphin neuronal transmission within the periaqueductal gray of the rat
    • (1994) Brain Res , vol.667 , pp. 283-286
    • Hawranko, A.A.1    Monroe, P.J.2    Smith, D.J.3
  • 32
    • 0023808936 scopus 로고
    • Influence of menstrual cycle on neuroendocrine and behavioral responses to an opiate agonist in humans: Preliminary results
    • (1988) Psychoneuroendocrinology , vol.13 , pp. 339-344
    • Hoehe, M.1
  • 47
    • 0029738663 scopus 로고    scopus 로고
    • The disposition of morphine and its 3- and 6-glucuronide metabolites in humans and animals, and the importance of the metabolites to the pharmacological effects of morphine
    • (1996) Drug Metab Rev , vol.28 , pp. 345-472
    • Milne, R.W.1    Nation, R.L.2    Somogyi, A.A.3
  • 51
    • 0025190756 scopus 로고
    • Morphine and metabolite behavior after different routes of morphine administration: Demonstration of the importance of the active metabolite morphine-6-glucuronide
    • (1990) Clin Pharmacol Ther , vol.47 , pp. 12-19
    • Osborne, R.1    Joel, S.2    Slevin, M.3
  • 56
    • 0002272622 scopus 로고
    • Effects of estradiol and testosterone on pharmacodynamics and pharmacokinetics of morphine in male rats
    • (1995) J Idaho Acad Sci , vol.31 , pp. 11-24
    • Ratka, A.1
  • 57
  • 65
    • 0022627065 scopus 로고
    • High-dose morphine and methadone in cancer patients. Clinical pharmacokinetic considerations of oral treatment
    • (1986) Clin Pharmacokinet , vol.11 , pp. 87-106
    • Sawe, J.1
  • 68
    • 0029022563 scopus 로고
    • Morphine-3-glucuronide: Evidence to support its putative role in the development of tolerance to the antinociceptive effects of morphine in the rat
    • (1995) Pain , vol.62 , pp. 51-60
    • Smith, G.D.1    Smith, M.T.2
  • 70
    • 50849150363 scopus 로고
    • A method for frequent sampling of blood and continuous infusion of fluids in the rat without disturbing the animal
    • (1969) Physiol Behav , vol.4 , pp. 833-837
    • Steffens, A.B.1
  • 74
    • 0025021645 scopus 로고
    • Fast reliable assay for morphine and its metabolites using high-performance liquid chromatography and native fluorescence
    • (1990) J Chromatogr , vol.525 , pp. 379-388
    • Venn, R.F.1    Michalkiewicz, A.2
  • 76
    • 0029063116 scopus 로고
    • Plasma concentrations of morphine, morphine-3-glucuronide, and morphine-6-glucuronide after intravenous and oral administration to healthy volunteers: Relationship to nonanalgesic actions
    • (1995) Therap Drug Monit , vol.17 , pp. 287-301
    • Westerling, D.1    Persson, C.2    Hoglund, P.3
  • 77
    • 0019524261 scopus 로고
    • Intrathecal high dose morphine produced hyperalgesia in the rat
    • (1981) Brain Res , vol.209 , pp. 491-495
    • Woolf, C.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.